Chercheur(e)

Dr Richard Debigaré

Pneumologie

richard.debigare@criucpq.ulaval.ca

Publications

Trier par année :

Marquis K, Debigaré R, Lacasse Y, LeBlanc P, Jobin J, Carrier G, Maltais F. Midthigh muscle cross-sectional area is a better predictor of mortality than body mass index in patients with chronic obstructive pulmonary disease.. Am J Respir Crit Care Med 2002; 166(6):809-13.
Maltais F, Debigaré R. Biology of muscle impairment in COPD.. Monaldi Arch Chest Dis 2003; 59(4):338-41.
Debigaré R, Marquis K, Côté CH, Tremblay RR, Michaud A, LeBlanc P, Maltais F. Catabolic/anabolic balance and muscle wasting in patients with COPD.. Chest 2003; 124(1):83-9.
Debigaré R, Price SR. Proteolysis, the ubiquitin-proteasome system, and renal diseases.. Am J Physiol Renal Physiol 2003; 285(1):F1-8.
Saey D, Debigaré R, LeBlanc P, Mador MJ, Côté CH, Jobin J, Maltais F. Contractile leg fatigue after cycle exercise: a factor limiting exercise in patients with chronic obstructive pulmonary disease.. Am J Respir Crit Care Med 2003; 168(4):425-30.
Couillard A, Maltais F, Saey D, Debigaré R, Michaud A, Koechlin C, LeBlanc P, Préfaut C. Exercise-induced quadriceps oxidative stress and peripheral muscle dysfunction in patients with chronic obstructive pulmonary disease.. Am J Respir Crit Care Med 2003; 167(12):1664-9.
Debigaré R, Côté CH, Hould FS, LeBlanc P, Maltais F. In vitro and in vivo contractile properties of the vastus lateralis muscle in males with COPD.. Eur Respir J 2003; 21(2):273-8.
Russell AP, Somm E, Debigaré R, Hartley O, Richard D, Gastaldi G, Melotti A, Michaud A, Giacobino JP, Muzzin P, LeBlanc P, Maltais F. COPD results in a reduction in UCP3 long mRNA and UCP3 protein content in types I and IIa skeletal muscle fibers.. J Cardiopulm Rehabil 2004; 24(5):332-9.
Doucet M, Debigaré R, Joanisse DR, Côté C, LeBlanc P, Gregoire J, Deslauriers J, Vaillancourt R, Maltais F. Adaptation of the diaphragm and the vastus lateralis in mild-to-moderate COPD.. Eur Respir J 2004; 24(6):971-9.
Du J, Wang X, Miereles C, Bailey JL, Debigaré R, Zheng B, Price SR, Mitch WE. Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions.. J Clin Invest 2004; 113(1):115-23.
Debigaré R, LeBlanc P, Maltais F. Exercise training and peripheral muscle dysfunction in patients with chronic obstructive pulmonary disease. Am J Sports Med 2003; 5(0):48-53.
Marquis K, Debigaré R, Lacasse Y, Leblanc P, Jobin J, Maltais F. Mid-thigh cross-sectional area is a better predictor of mortality than a body mass index in patients with COPD.. Am J Respir Crit Care Med 2002; 166(0):809-813.
Debigaré R, Milot J, Côté CH, Michaud A, Leblanc P, Maltais F. Blood and peripheral muscle pro-inflamatory cytokines in patients with COPD.. Am J Respir Crit Care Med 2002; 163(5):A287.
Aliverti A, Macklem PT, Debigare R, Maltais F, O'Donnell DE, Webb KA. Point: Counterpoint - The major limitations to exercise performance in COPD.. J Appl Physiol 2008; 105(0):751-753.
Doucet M, Russell AP, Léger B, Debigaré R, Joanisse DR, Caron MA, LeBlanc P, Maltais F. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.. Am J Respir Crit Care Med 2007; 176(3):261-9.
Debigaré R, Maltais F. The major limitation to exercise performance in COPD is lower limb muscle dysfunction.. J Appl Physiol 2008; 105(2):751-3.
Maltais F, Saey D, Debigaré R. Enhancing the benefits of pulmonary rehabilitation: doing more for a few or doing a little less for many?. Am J Respir Crit Care Med 2008; 178(3):215-6.
Debigaré R, Maltais F, Côté CH, Michaud A, Caron MA, Mofarrahi M, Leblanc P, Hussain SN. Profiling of mRNA expression in quadriceps of patients with COPD and muscle wasting.. COPD 2008; 5(2):75-84.
Debigaré R, Côté CH, Maltais F. Ubiquitination and proteolysis in limb and respiratory muscles of patients with chronic obstructive pulmonary disease.. Proc Am Thorac Soc 2010; 7(1):84-90.
Debigaré R, Maltais F. Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation.. J Appl Physiol 2008; 105(2):764.
Caron MA, Debigaré R, Dekhuikzen PN, Maltais F. Comparative Assessment of the Quadriceps and the Diaphragm in Patients with COPD.. J Appl Physiol 2009; 107(3):952-61.
Caron MA, Thériault ME, Paré ME, Maltais F, Debigaré R. Hypoxia alters contractile protein homeostasis in L6 myotubes.. FEBS Lett 2009; 583(9):1528-34.
Marquis N, Debigaré R, Bouyer L, Saey D, Laviolette L, Brouillard C, Maltais F. Physiology of walking in patients with moderate to severe chronic obstructive pulmonary disease.. Med Sci Sports Exerc 2009; 41(8):1540-8.
Kim HC, Mofarrahi M, Vassilokopoulos T, Maltais F, Sigala I, Debigare R, Bellenis I, Hussain SN. Expression and Functional Significance of Nicotinamide N-methyl Transferase (NNMT) in Skeletal Muscles of Patients with COPD.. Am J Respir Crit Care Med 2010; 181(8):797-805.
Doucet M, Dubé A, Joanisse DR, Debigaré R, Michaud A, Paré MÈ, Vaillancourt R, Fréchette E, Maltais F. Atrophy and hypertrophy signalling of the quadriceps and diaphragm in COPD.. Thorax 2010; 65(11):963-70.
Marciniuk DD, Brooks D, Butcher S, Debigare R, Dechman G, Ford G, Pepin V, Reid D, Sheel AW, Stickland MK, Todd DC, Walker SL, Aaron SD, Balter M, Bourbeau J, Hernandez P, Maltais F, O'Donnell DE, Bleakney D, Carlin B, Goldstein R, Muthuri SK, . Optimizing pulmonary rehabilitation in chronic obstructive pulmonary disease--practical issues: a Canadian Thoracic Society Clinical Practice Guideline.. Can Respir J 2010; 17(4):159-68.
Saey D, Lemire BB, Gagnon P, Bombardier E, Tupling AR, Debigaré R, Côté CH, Maltais F. Quadriceps metabolism during constant workrate cycling exercise in chronic obstructive pulmonary disease.. J Appl Physiol 2011; 110(1):116-24.
Guo Y, Gosker HR, Schols AM, Kapchinsky S, Bourbeau J, Sandri M, Jagoe RT, Debigaré R, Maltais F, Taivassalo T, Hussain SN. Autophagy in locomotor muscles of patients with chronic obstructive pulmonary disease.. Am J Respir Crit Care Med 2013; 188(11):1313-20.
Caron MA, Debigaré R, Dekhuijzen PN, Maltais F. [Diaphragm and skeletal muscle dysfunction in COPD].. Rev Mal Respir 2011; 28(10):1250-64.
Caron MA, Charette SJ, Maltais F, Debigaré R. Variability of protein level and phosphorylation status caused by biopsy protocol design in human skeletal muscle analyses.. BMC Res Notes 2011; 4(0):488.
Vivodtzev I, Debigaré R, Gagnon P, Mainguy V, Saey D, Dubé A, Paré MÈ, Bélanger M, Maltais F. Functional and Muscular effects of neuromuscular electrical stimulation in patients with severe COPD: a randomized clinical trial.. Chest 2012; 141(3):716-25.
Ribeiro F, Thériault ME, Debigare R, Maltais F. Should all patients with COPD be exercise-trained?. J Appl Physiol 2013; 114(9):1300-8.
Mofarrahi M, Sigala I, Vassilakopoulos T, Harel S, Guo Y, Debigare R, Maltais F, Hussain SN. Angiogenesis-related factors in skeletal muscles of COPD patients: roles of angiopoietin-2.. J Appl Physiol 2013; 114(9):1309-18.
Thériault ME, Paré MÈ, Maltais F, Debigaré R. Satellite cells senescence in limb muscle of severe patients with COPD.. PLoS One 2012; 7(6):e39124.
Lemire BB, Debigaré R, Dubé A, Thériault ME, Côté CH, Maltais F. MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease.. J Appl Physiol 2012; 113(1):159-66.
Caron MA, Morissette MC, Thériault ME, Nikota JK, Stämpfli MR, Debigaré R.. Alterations in skeletal muscle cell homeostasis in a mouse model of cigarette smoke exposure.. PLoS One 2013; 8(6):e66433.
Maltais F, Decramer M, Casaburi R, Barreiro E, Burelle Y, Debigaré R, Dekhuijzen PN, Franssen F, Gayan-Ramirez G, Gea J, Gosker HR, Gosselink R, Hayot M, Hussain SN, Janssens W, Polkey MI, Roca J, Saey D, Schols AM, Spruit MA, Steiner M, Taivassalo T, Troosters T, Vogiatzis I, Wagner PD. An official american thoracic society/european respiratory society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease.. Am J Respir Crit Care Med 2014; 189(9):e15-62.
Thériault ME, Paré MÈ, Lemire BB, Maltais F, Debigaré R. Regenerative defect in vastus lateralis muscle of patients with chronic obstructive pulmonary disease.. Respir Res 2014; 15(0):35.
Gagnon P, Lemire BB, Dubé A, Saey D, Porlier A, Croteau M, Provencher S, Debigaré R, Maltais F. Preserved function and reduced angiogenesis potential of the quadriceps in patients with mild COPD.. Respir Res 2014; 15(0):4.
Camp PG, Hernandez P, Bourbeau J, Kirkham A, Debigare R, Stickland M, Goodridge D, Marciniuk D, Road J, Bhutani M, Dechman G. Pulmonary rehabilitation in Canada: A report from the Canadian Thoracic Society COPD Clinical Assembly.. Can Respir J 2015; 22(3):147-52.
Sallé-Lefort S, Miard S, Nolin MA, Boivin L, Paré MÈ, Debigaré R, Picard F. Hypoxia upregulates Malat1 expression through a CaMKK/AMPK/HIF-1? axis.. Int J Oncol 2016; 49(4):1731-6.
Pagé M, Maheux C, Langlois A, Brassard J, Bernatchez É, Martineau S, Henry C, Beaulieu MJ, Bossé Y, Morissette MC, Debigaré R, Blanchet MR. CD34 regulates the skeletal muscle response to hypoxia.. J Muscle Res Cell Motil 2019; 40(3):309-318.
Iqbal MZ, Rochette A, Mayo NE, Valois MF, Bussières AE, Ahmed S, Debigaré R, Letts LJ, MacDermid JC, Ogourtsova T, Polatajko HJ, Rappolt S, Salbach NM, Thomas A. Exploring if and how evidence-based practice of occupational and physical therapists evolves over time: A longitudinal mixed methods national study.. PLoS One 2023; 18(3):e0283860.
Thomas A, Roberge-Dao J, Iqbal MZ, Salbach NM, Letts LJ, Polatajko HJ, Rappolt S, Debigaré R, Ahmed S, Bussières A, Paterson M, Rochette A. Developing multisectoral strategies to promote evidence-based practice in rehabilitation: findings from an end-of-grant knowledge translation symposium.. Disabil Rehabil 2023; 0(0):1-12.

Dr Richard Debigaré

Publications

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