- Accueil
- Chercheurs
- Dr Mathieu Morissette
Publications
44- Jobse BN, McCurry CA, Morissette MC, Rhem RG, Stämpfli MR, Labiris NR.. Impact of inflammation, emphysema, and smoking cessation on V/Q in mouse models of lung obstruction.. Respir Res 2014; 15(0):42.
- Nikota JK, Shen P, Morissette MC, Fernandes K, Roos A, Chu DK, Barra NG, Iwakura Y, Kolbeck R, Humbles AA, Stampfli MR.. Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice.. J Immunol 2014; 193(6):3134-45.
- Morissette MC, Lamontagne M, Bérubé JC, Gaschler G, Williams A, Yauk C, Couture C, Laviolette M, Hogg JC, Timens W, Halappanavar S, Stampfli MR, Bossé Y. Impact of cigarette smoke on the human and mouse lungs: a gene-expression comparison study.. PLoS One 2014; 9(3):e92498.
- Morissette MC, P Shen, D Thayaparan and MR Stämpfli. Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation.. Eur Respir J 2015; 46(5):1451-60.
- Morissette MC, Jobse BN, Thayaparan D, Nikota JK, Shen P, Labiris NR, Kolbeck R, Nair P, Humbles AA, Stämpfli MR.. Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure. Respir Res 2014; 15(0):49.
- Boucherat O, Morissette MC, Provencher S, Bonnet S, Maltais F. Bridging Lung Development with Chronic Obstructive Pulmonary Disease. Relevance of Developmental Pathways in Chronic Obstructive Pulmonary Disease Pathogenesis.. Am J Respir Crit Care Med 2016; 193(4):362-75.
- Shen P, Morissette MC, Vanderstocken G, Gao Y, Hassan M, Roos A, Thayaparan D, Merlano M, Dorrington MG, Nikota JK, Bauer CM, Kwiecien JM, Labiris R, Bowdish DM, Stevenson CS, Stämpfli MR. Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice.. Infect Immun 2016; 84(5):1536-47.
- Morissette MC, Murray N, Turmel J, Milot J, Boulet LP, Bougault V. Increased exhaled breath condensate 8-isoprostane after a swimming session in competitive swimmers.. Eur J Sport Sci 2015; 0(0):1-8.
- Morissette MC, Shen P, Thayaparan D, Stämpfli MR.. Impacts of peroxisome proliferator-activated receptor-γ activation on cigarette smoke-induced exacerbated response to bacteria.. Eur Respir J 2015; 45(1):191-200.
- Thayaparan D, Shen P, Stämpfli MR, Morissette MC.. Induction of pulmonary antibodies against oxidized lipids in mice exposed to cigarette smoke.. Respir Res 2016; 17(1):97.
- Jubinville É, Talbot M, Bérubé JC, Hamel-Auger M, Maranda-Robitaille M, Beaulieu MJ, Aubin S, Paré MÈ, Kallend DG, Arsenault B, Bossé Y, Morissette MC. Interplay between cigarette smoking and pulmonary reverse lipid transport.. Eur Respir J 2017; 50(3):1700681.
- Boulay MÈ, Henry C, Bossé Y, Boulet LP, Morissette MC. Acute effects of nicotine-free and flavour-free electronic cigarette use on lung functions in healthy and asthmatic individuals.. Respir Res 2017; 18(1):33.
- Huppé CA, Blais-Lecours P, Lechasseur A, Gendron DR, Lemay AM, Bissonnette EY, Blanchet MR, Duchaine C, Morissette MC, Rosen H, Marsolais D. A sphingosine-1-phosphate receptor 1 agonist inhibits tertiary lymphoid tissue reactivation and hypersensitivity in the lung.. Mucosal Immunol 2018; 11(1):112-119.
- Lechasseur A, Jubinville É, Routhier J, Bérubé JC, Hamel-Auger M, Talbot M, Lamothe J, Aubin S, Paré MÈ, Beaulieu MJ, Bossé Y, Duchaine C, Morissette MC. Exposure to electronic cigarette vapors affects pulmonary and systemic expression of circadian molecular clock genes.. Physiol Rep 2017; 5(19):e13440.
- Mailhot-Larouche S, Deschênes L, Gazzola M, Lortie K, Henry C, Brook BS, Morissette MC, Bossé Y. Repeated airway constrictions in mice do not alter respiratory function.. J Appl Physiol (1985) 2018; 124(6):1483-1490.
- Talbot M, Hamel-Auger M, Beaulieu MJ, Gazzola M, Lechasseur A, Aubin S, Paré MÈ, Marsolais D, Bossé Y, Morissette MC. Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice.. Respir Res 2018; 19(1):131.
- Clemenceau A, Boucherat O, Landry-Truchon K, Lamontagne M, Biardel S, Joubert P, Gobeil S, Secco B, Laplante M, Morissette M, Obeidat M, Timens W, Jeannotte L, Bossé Y.. Lung cancer susceptibility genetic variants modulate HOXB2 expression in the lung.. Int J Dev Biol 2018; 62(11):857-864.
- Jubinville É, Routhier J, Maranda-Robitaille M, Pineault M, Milad N, Talbot M, Beaulieu MJ, Aubin S, Paré MÈ, Laplante M, Morissette MC. Pharmacological activation of Liver X Receptor during cigarette smoke exposure adversely affects alveolar macrophages and pulmonary surfactant homeostasis.. Am J Physiol Lung Cell Mol Physiol 2019; 316(4):L669-L678.
- Bossé Y, Lamontagne M, Gaudreault N, Racine C, Levesque MH, Smith BM, Auger D, Clemenceau A, Paré MÈ, Laviolette L, Tremblay V, Maranda B, Morissette MC, Maltais F.. Early-onset emphysema in a large French-Canadian family: a genetic investigation.. Lancet Respir Med 2019; 7(5):427-436.
- Lechasseur A, Altmejd S, Turgeon N, Buonanno G, Morawska L, Brunet D, Duchaine C, Morissette MC.. Variations in coil temperature/power and e-liquid constituents change size and lung deposition of particles emitted by an electronic cigarette.. Physiol Rep 2019; 7(10):e14093.
- Parraga G, Morissette MC. E-cigarettes: What evidence links vaping to acute lung injury and respiratory failure?. Can J Respir Crit Care Sleep Med 2020; 4(1):48-54.
- Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, Guénard F, Festuccia WT, Joubert P, Rose CF, Karvellas CJ, Barbier O, Morissette MC, Marette A, Laplante M. The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis.. JCI Insight 2019; 4(15):129492.
- Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, Guénard F, Festuccia WT, Joubert P, Rose CF, Karvellas CJ, Barbier O, Morissette MC, Marette A, Laplante M. The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis.. Mol Metab 2019; 30(0):184-191.
- Pagé M, Maheux C, Langlois A, Brassard J, Bernatchez É, Martineau S, Henry C, Beaulieu MJ, Bossé Y, Morissette MC, Debigaré R, Blanchet MR. CD34 regulates the skeletal muscle response to hypoxia.. J Muscle Res Cell Motil 2019; 40(3):309-318.
- White Z, Milad N, Tehrani AY, Lamothe J, Hogg JC, Esfandiarei M, Seidman M, Booth S, Hackett TL, Morissette MC, Bernatchez P.. Sildenafil Prevents Marfan-Associated Emphysema and Early Pulmonary Artery Dilation in Mice.. Am J Pathol 2019; 189(8):1536-1546.
- Huppé CA, Blais-Lecours P, Bernatchez E, Lauzon-Joset JF, Duchaine C, Rosen H, Dion G, McNagny KM, Blanchet MR, Morissette MC, Marsolais D. S1P1 Contributes to Endotoxin-enhanced B-Cell Functions Involved in Hypersensitivity Pneumonitis.. Am J Respir Cell Mol Biol 2020; 63(2):209-218.
- Lechasseur A, Huppé CA, Talbot M, Routhier J, Aubin S, Beaulieu MJ, Duchaine C, Marsolais D, Morissette MC. Exposure to nicotine-free and flavor-free e-cigarette vapors modifies the pulmonary response to tobacco cigarette smoke in female mice.. Am J Physiol Lung Cell Mol Physiol 2020; 319(4):L717-L727.
- Jubinville É, Milad N, Maranda-Robitaille M, Lafrance MA, Pineault M, Lamothe J, Routhier J, Beaulieu MJ, Aubin S, Laplante M, Morissette MC. Critical importance of dietary methionine and choline in the maintenance of lung homeostasis during normal and cigarette smoke exposure conditions.. Am J Physiol Lung Cell Mol Physiol 2020; 319(2):L391-L402.
- Milad N, Pineault M, Lechasseur A, Routhier J, Beaulieu MJ, Aubin S, Morissette MC.. Neutrophils and IL-1α Regulate Surfactant Homeostasis during Cigarette Smoking.. J Immunol 2021; 206(8):1923-1931.
- Lechasseur A, Morissette MC.. The fog, the attractive and the addictive: pulmonary effects of vaping with a focus on the contribution of each major vaping liquid constituent.. Eur Respir Rev 2020; 29(157):200268.
- Khadangi F, Forgues AS, Tremblay-Pitre S, Dufour-Mailhot A, Henry C, Boucher M, Beaulieu MJ, Morissette M, Fereydoonzad L, Brunet D, Robichaud A, Bossé Y. Intranasal versus intratracheal exposure to lipopolysaccharides in a murine model of acute respiratory distress syndrome.. Sci Rep 2021; 11(1):7777.
- Nyberg A, Martin M, Saey D, Milad N, Patoine D, Morissette MC, Auger D, Stål P, Maltais F. Effects of Low-Load/High-Repetition Resistance Training on Exercise Capacity, Health Status, and Limb Muscle Adaptation in Patients With Severe COPD: A Randomized Controlled Trial.. Chest 2021; 159(5):1821-1832.
- Morissette M, Godbout K, Côté A, Boulet LP. Asthma COPD overlap: Insights into cellular and molecular mechanisms.. Mol Aspects Med 2021; 0(0):101021.
- Lechasseur A, Mouchiroud M, Tremblay F, Bouffard G, Milad N, Pineault M, Maranda-Robitaille M, Routhier J, Beaulieu MJ, Aubin S, Laplante M, Morissette MC. Glycerol contained in vaping liquids affects the liver and aspects of energy homeostasis in a sex-dependent manner.. Physiol Rep 2022; 10(2):e15146.
- McGrath JJC, Vanderstocken G, Dvorkin-Gheva A, Cass SP, Afkhami S, Fantauzzi MF, Thayaparan D, Reihani A, Wang P, Beaulieu A, Shen P, Morissette M, Jiménez-Saiz R, Revill SD, Tabuchi A, Zabini D, Lee WL, Richards CD, Miller MS, Ask K, Kuebler WM, Simpson JA, Stämpfli MR. Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar-capillary barrier function during influenza infection.. Eur Respir J 2022; 60(2):2102049.
- Milad N, Morissette MC.. Revisiting the role of pulmonary surfactant in chronic inflammatory lung diseases and environmental exposure.. Eur Respir Rev 2021; 30(162):210077.
- Courtemanche O, Huppé CA, Blais Lecours P, Lerdu O, Roy J, Lauzon-Joset JF, Blanchet MR, Morissette MC, Marsolais D. Co-modulation of T cells and B cells enhances the inhibition of inflammation in experimental hypersensitivity pneumonitis.. Respir Res 2022; 23(1):275.
- Sallé-Lefort S, Miard S, Henry C, Arias-Reyes C, Marcouiller F, Beaulieu MJ, Aubin S, Lechasseur A, Jubinville É, Marsolais D, Morissette MC, Joseph V, Soliz J, Bossé Y, Picard F. Malat1 deficiency prevents hypoxia-induced lung dysfunction by protecting the access to alveoli.. Front Physiol 2022; 13(0):949378.
- Pelletier G, Godbout K, Boulay MÈ, Boulet LP, Morissette MC, Côté A. Increase in FeNO Levels Following IL5/IL5R-Targeting Therapies in Severe Asthma: A Case Series.. J Asthma Allergy 2022; 15(0):691-701.
- Morissette M, Godbout K, Côté A, Boulet LP. Asthma COPD overlap: Insights into cellular and molecular mechanisms.. Mol Aspects Med 2022; 85(0):101021.
- Pelletier É, Desmeules P, Lacasse Y, Tanguay S, Milot J, Morissette MC, Maltais F. Antibody Response to Severe Acute Respiratory Syndrome Coronavirus-2 Vaccination in COPD: A Cohort Study.. Chronic Obstr Pulm Dis 2022; 9(4):591-595.
- Nyberg A, Milad N, Martin M, Patoine D, Morissette MC, Saey D, Maltais F. Role of progression of training volume on intramuscular adaptations in patients with chronic obstructive pulmonary disease.. Front Physiol 2022; 13(0):873465.
- Milad N, Pineault M, Bouffard G, Maranda-Robitaille M, Lechasseur A, Beaulieu MJ, Aubin S, Jensen BAH, Morissette MC.. Recombinant human β-defensin 2 delivery improves smoking-induced lung neutrophilia and bacterial exacerbation.. Am J Physiol Lung Cell Mol Physiol 2022; 323(1):L37-L47.
- Milad N, Pineault M, Tremblay F, Routhier J, Lechasseur A, Beaulieu MJ, Aubin S, Morissette MC.. Smoking status impacts treatment efficacy in smoke-induced lung inflammation: A pre-clinical study.. Front Pharmacol 2022; 13(0):971238.