Chercheur(e)

Dr Marie-Annick Clavel

Cardiologie

Y3185

marie-annick.clavel@criucpq.ulaval.ca

Domaine de recherche

Identification des différences liées au sexe dans la pathophysiologie, la présentation, le traitement et le devenir des patients atteints de sténose aortique.

Identification des différences liées au sexe dans la pathophysiologie, la présentation, le traitement et le devenir des patients atteints d'insuffisance mitrale.

Description des travaux

Dre Clavel, professeure titulaire depuis 2023 de la faculté de médecine de l'Université Laval et chercheuse au Centre de recherche de l'IUCPQ-ULaval, poursuit ses travaux de recherche dans le domaine des maladies valvulaires. Dre Clavel a déjà publié plus de 250 articles scientifiques et plus de 500 résumés à des congrès nationaux et internationaux. Depuis 2020, Dre Clavel est titulaire de la Chaire de recherche du Canada sur la santé valvulaire cardiaque des femmes. Elle est également titulaire d'une bourse de recherche de jeune chercheur du Fonds de recherche du Québec en santé et de subventions de recherche de la Fondation IUCPQ, de l'Université Laval et de la Fondation des maladies du coeur du Canada. Elle a reçu plusieurs prix de présentation scientifique et le prix d'excellence 2017 de la Fondation des maladies du coeur du Québec et de la Fondation Jacques-de-Champlain. Elle a fondé et dirige le laboratoire d'identification et d'application des différences sexuelles dans les maladies valvulaires cardiaques (Laboratory for identification and application of differences between sexes in valvular Heart diseases - LIADIS) et le laboratoire central d'analyses radiologiques valvulaires (Valvular Radiologic Multi-Imaging core laboratory - VaRMI-CL).

La sténose aortique est la troisième maladie cardiovasculaire la plus importante dans les pays à revenu élevé. Cette atteinte de la valve aortique est caractérisée par une calcification et une fibrose importante des tissus valvulaires qui conduiront à l'obstruction du flot sanguin entre le ventricule gauche et l'aorte. Depuis des années, la sténose aortique est étudiée dans des modèles animaux entièrement masculins dans le but de minimiser l'hétérogénéité et dans des cohortes majoritairement composées d'hommes car le sexe masculin a été présenté comme un facteur de risque de la maladie. Ainsi, notre compréhension du rôle qu'à le sexe dans la pathophysiologie, la présentation et le devenir des patients atteints de sténose aortique limite notre habileté à personnaliser la prise en charge des patients et à optimiser leur traitement pour un meilleur devenir. Dans de récents travaux, Dre Clavel et son équipe a démontré que pour une même sévérité hémodynamique de la maladie, les femmes avaient une charge calcique valvulaire moins importante que les hommes. Cette différence serait expliquée par une plus grande fibrose de la valve aortique chez la femme et une calcification plus importante chez l'homme.

La régurgitation mitrale est la seconde maladie valvulaire le plus prévalente (après la sténose aortique). Les femmes semblent plus atteintes par cette maladie, cependant les hommes sont plus souvent référés en chirurgie. De façon intéressante, nous avons démontrer que l'application des seuils de sévérité proposés dans les guides de pratiques, sans indexation par rapport à la surface corporelle ou la taille du coeur du patients avaient une tendance à sous-estimer la maladie chez la femme. Ceci conduirait à un délai au traitement voire une absence de traitement marqués chez les femmes et donc un devenir plus sombre.
L'objectif global du programme de recherche du Dre Clavel est de caractériser les différences entre hommes et femmes dans la physiopathologie, le diagnostic et le traitement des maladies valvulaires. Les études menant à l'atteinte de cet objectif global seront effectuées sur des données disponibles provenant de cohortes humaines, de valves humaines explantées, de cellules interstitielles valvulaires, de modèles murins de sténose aortique, et des études interventionnelles prospectives chez des patients. Le premier objectif de ce programme est de documenter la prévalence, la présentation au moment du diagnostic et le devenir clinique des patients atteints de maladie valvulaires en fonction du sexe. Le deuxième objectif est d'étudier la modulation du système rénine-angiotensine (RAS) et des hormones sexuelles dans les différences liées au sexe de la physiopathologie de la sténose aortique. Le troisième objectif est d'évaluer un modèle murin existant de sténose aortique qui imite les différences liées au sexe dans la physiopathologie de la sténose aortique et d'explorer les mécanismes qui expliquent ces différences. Enfin, le quatrième objectif consiste à utiliser ce modèle murin pour évaluer l'effet de diverses thérapies sur le taux de progression de la maladie et pour déterminer si l'ampleur de cet effet diffère entre les femelles et les males. Le programme du Dre Clavel vise à apporter de nouvelles connaissances et à sensibiliser davantage à la spécificité sexuelle dans la pathophysiologie et l'épidémiologie des maladies valvulaires et à la nécessité d'une prise en charge spécifique au sexe afin d'améliorer le devenir des patients. Ainsi, les résultats de son programme de recherche pourraient avoir un impact important sur les lignes directrices pour la gestion des patients atteints de maladies valvulaires, en établissant des lignes directrices spécifiques pour les femmes et les hommes.

Publications

286

Trier par année :

Clavel MA, Mantovani F, Malouf J, Michelena HI, Vatury O, Jain MS, Mankad SV, Suri RM, Enriquez-Sarano M. Dynamic phenotypes of degenerative myxomatous mitral valve disease: quantitative 3-dimensional echocardiographic study.. Circ Cardiovasc Imaging 2015; 8(5):e002989.
Clavel MA, Malouf J, Messika-Zeitoun D, Araoz PA, Michelena HI, Enriquez-Sarano M. Aortic valve area calculation in aortic stenosis by CT and Doppler echocardiography.. JACC Cardiovasc Imaging 2015; 8(3):248-57.
Ribeiro HB, Urena M, Le Ven F, Nombela-Franco L, Allende R, Clavel MA, Dahou A, Côté M, Laflamme J, Laflamme L, Delarochellière H, Delarochellière R, Doyle D, Dumont E, Bergeron S, Pibarot P, Rodés-Cabau J. Long-term prognostic value and serial changes of plasma N-terminal prohormone B-type natriuretic Peptide in patients undergoing transcatheter aortic valve implantation.. Am J Cardiol 2014; 113(5):851-9.
Capoulade R, Larose E, Mathieu P, Clavel MA, Dahou A, Arsenault M, Bédard E, Larue-Grondin S, Le Ven F, Dumesnil JG, Després JP, Pibarot P.. Visceral adiposity and left ventricular mass and function in patients with aortic stenosis: The PROGRESSA Study.. Can J Cardiol 2014; 30(9):1080-7.
Clavel MA, Côté N, Mathieu P, Dumesnil JG, Audet A, Pépin A, Couture C, Fournier D, Trahan S, Pagé S, Pibarot P. Paradoxical low-flow, low-gradient aortic stenosis despite preserved left ventricular ejection fraction: new insights from weights of operatively excised aortic valves.. Eur Heart J 2014; 35(38):2655-62.
Clavel MA, Pibarot P, Dumesnil JG. Paradoxical low flow aortic valve stenosis: incidence, evaluation, and clinical significance.. Curr Cardiol Rep 2014; 16(1):431.
Dahou A, Magne J, Clavel MA, Capoulade R, Bartko PE, Bergler-Klein J, Sénéchal M, Mundigler G, Burwash I, Ribeiro HB, O'Connor K, Mathieu P, Baumgartner H, Dumesnil JG, Rosenhek R, Larose É, Rodés-Cabau J, Pibarot P. Tricuspid Regurgitation Is Associated With Increased Risk of Mortality in Patients With Low-Flow Low-Gradient Aortic Stenosis and Reduced Ejection Fraction: Results of the Multicenter TOPAS Study (True or Pseudo-Severe Aortic Stenosis).. JACC Cardiovasc Interv 2015; 8(4):588-96.
Mantovani F, Clavel MA, Vatury O, Suri RM, Mankad SV, Malouf J, Michelena HI, Jain S, Badano LP, Enriquez-Sarano M. Cleft-like indentations in myxomatous mitral valves by three-dimensional echocardiographic imaging.. Heart 2015; 101(14):1111-7.
Nguyen V, Cimadevilla C, Estellat C, Codogno I, Huart V, Benessiano J, Duval X, Pibarot P, Clavel MA, Enriquez-Sarano M, Vahanian A, Messika-Zeitoun D. Haemodynamic and anatomic progression of aortic stenosis.. Heart 2015; 101(12):943-7.
Ribeiro HB, Le Ven F, Larose É, Dahou A, Nombela-Franco L, Urena M, Allende R, Amat-Santos I, Ricapito Mde L, Thébault C, Clavel MA, Delarochelliére R, Doyle D, Dumont É, Dumesnil JG1, Pibarot P1, Rodés-Cabau J1. Cardiac magnetic resonance versus transthoracic echocardiography for the assessment and quantification of aortic regurgitation in patients undergoing transcatheter aortic valve implantation.. Heart 2014; 100(24):1924-32.
Clavel MA, Dumesnil JG, Pibarot P.. Discordant grading of aortic stenosis using echocardiography and what it means: new insights from magnetic resonance imaging.. Can J Cardiol 2014; 30(9):959-61.
Clavel MA, Malouf J, Michelena HI, Suri RM, Jaffe AS, Mahoney DW, Enriquez-Sarano M.. B-type natriuretic peptide clinical activation in aortic stenosis: impact on long-term survival.. J Am Coll Cardiol 2014; 63(19):2016-25.
Clavel MA, Berthelot-Richer M, Le Ven F, Capoulade R, Dahou A, Dumesnil JG, Mathieu P, Pibarot P.. Impact of classic and paradoxical low flow on survival after aortic valve replacement for severe aortic stenosis.. J Am Coll Cardiol 2015; 65(7):645-53.
Dahou A, Bartko PE, Capoulade R, Clavel MA, Mundigler G, Grondin SL, Bergler-Klein J, Burwash I, Dumesnil JG, Sénéchal M, O'Connor K, Baumgartner H, Pibarot P.. Usefulness of global left ventricular longitudinal strain for risk stratification in low ejection fraction, low-gradient aortic stenosis: results from the multicenter True or Pseudo-Severe Aortic Stenosis study.. Circ Cardiovasc Imaging 2015; 8(3):e002117.
Clavel MA, Pibarot P. Assessment of low-flow, low-gradient aortic stenosis: multimodality imaging is the key to success.. EuroIntervention 2014; 10(0):U52-60.
Clavel MA, Pibarot P, Messika-Zeitoun D, Capoulade R, Malouf J, Aggarval S, Araoz PA, Michelena HI, Cueff C, Larose E, Miller JD, Vahanian A, Enriquez-Sarano M. Impact of aortic valve calcification, as measured by MDCT, on survival in patients with aortic stenosis: results of an international registry study.. J Am Coll Cardiol 2014; 64(12):1202-13.
Capoulade R, Côté N, Mathieu P, Chan KL, Clavel MA, Dumesnil JG, Teo KK, Tam JW, Fournier D, Després JP, Pibarot P. Circulating levels of matrix gla protein and progression of aortic stenosis: a substudy of the Aortic Stenosis Progression Observation: Measuring Effects of rosuvastatin (ASTRONOMER) trial.. Can J Cardiol 2014; 30(9):1088-95.
Pressman GS, Movva R, Topilsky Y, Clavel MA, Saldanha JA, Watanabe N, Enriquez-Sarano M. Mitral Annular Dynamics in Mitral Annular Calcification: A Three-Dimensional Imaging Study.. J Am Soc Echocardiogr 2015; 28(7):786-94.
Pibarot P, Clavel MA. Management of paradoxical low-flow, low-gradient aortic stenosis: need for an integrated approach, including assessment of symptoms, hypertension, and stenosis severity.. J Am Coll Cardiol 2015; 65(1):67-71.
Pibarot P, Clavel MA, Dahou A. Patient and procedure selection for the prevention of prosthesis-patient mismatch following aortic valve replacement.. EuroIntervention 2015; 11(0):W106-9.
Clavel MA, Malouf J, Messika-Zeitoun D, Araoz PA, Michelena HI, Enriquez-Sarano M. Reply: Comparison of Echocardiography and CT for the Assessment of Aortic Stenosis Valve Area.. JACC Cardiovasc Imaging 2015; 8(9):1116.
Pressman GS, Movva R, Topilsky Y, Clavel MA, Saldanha JA, Watanabe N, Enriquez-Sarano M. Three-Dimensional Echocardiography: A Powerful New Tool in the Evaluation of Mitral Annular Structure and Dynamics.. J Am Soc Echocardiogr 2015; 28(10):1256-7.
Ribeiro HB, Larose É, de la Paz Ricapito M, Le Ven F, Nombela-Franco L, Urena M, Allende R, Amat-Santos I, Dahou A, Capoulade R, Clavel MA, Mohammadi S, Paradis JM, De Larochellière R, Doyle D, Dumont É, Pibarot P, Rodés-Cabau J. Myocardial injury following transcatheter aortic valve implantation: insights from delayed-enhancement cardiovascular magnetic resonance.. EuroIntervention 2015; 11(2):205-13.
Le Ven F, Thébault C, Dahou A, Ribeiro HB, Capoulade R, Mahjoub H, Urena M, Nombela-Franco L, Allende Carrera R, Clavel MA, Dumont É, Dumesnil J, De Larochellière R, Rodés-Cabau J, Pibarot P. Evolution and prognostic impact of low flow after transcatheter aortic valve replacement.. Heart 2015; 101(15):1196-203.
Enriquez-Sarano M, Suri RM, Clavel MA, Mantovani F, Michelena HI, Pislaru S, Mahoney DW, Schaff HV. Is there an outcome penalty linked to guideline-based indications for valvular surgery? Early and long-term analysis of patients with organic mitral regurgitation.. J Thorac Cardiovasc Surg 2015; 150(1):50-8.
Dayan V, Vignolo G, Magne J, Clavel MA, Mohty D, Pibarot P. Outcome and Impact of Aortic Valve Replacement in Patients With Preserved LVEF and Low-Gradient Aortic Stenosis.. J Am Coll Cardiol 2015; 66(23):2594-603.
Pibarot P, Clavel MA. Left ventricular outflow tract geometry and dynamics in aortic stenosis: implications for the echocardiographic assessment of aortic valve area.. J Am Soc Echocardiogr 2015; 28(11):1267-9.
Tastet L, Capoulade R, Clavel MA, Larose É, Shen M, Dahou A, Arsenault M, Mathieu P, Bédard É, Dumesnil JG, Tremblay A, Bossé Y, Després JP, Pibarot P. Systolic hypertension and progression of aortic valve calcification in patients with aortic stenosis: results from the PROGRESSA study.. Eur Heart J Cardiovasc Imaging 2017; 18(1):70-78.
Suri RM, Clavel MA, Schaff HV, Michelena HI, Huebner M, Nishimura RA, Enriquez-Sarano M. Effect of Recurrent Mitral Regurgitation Following Degenerative Mitral Valve Repair: Long-Term Analysis of Competing Outcomes.. J Am Coll Cardiol 2016; 67(5):488-98.
Dahou A, Clavel MA, Capoulade R, Bartko PE, Magne J, Mundigler G, Bergler-Klein J, Burwash I, Mascherbauer J, Ribeiro HB, O'Connor K, Baumgartner H, Sénéchal M, Dumesnil JG, Rosenhek R, Mathieu P, Larose E, Rodés-Cabau J, Pibarot P. Right ventricular longitudinal strain for risk stratification in low-flow, low-gradient aortic stenosis with low ejection fraction.. Heart 2016; 102(7):548-54.
Thaden JJ, Nkomo VT, Suri RM, Maleszewski JJ, Soderberg DJ, Clavel MA, Pislaru SV, Malouf JF, Foley TA, Oh JK, Miller JD, Edwards WD, Enriquez-Sarano M. Sex-related differences in calcific aortic stenosis: correlating clinical and echocardiographic characteristics and computed tomography aortic valve calcium score to excised aortic valve weight.. Eur Heart J 2016; 37(8):693-9.
Berthelot-Richer M, Bonenfant F, Clavel MA, Farand P, Philippon F, Ayala-Paredes F, Essadiqi B, Badra-Verdu MG, Roux JF. Arrhythmic Risk Following Recovery of Left Ventricular Ejection Fraction in Patients With Primary Prevention ICD.. Pacing Clin Electrophysiol 2016; 39(7):680-9.
Mantovani F, Clavel MA, Michelena HI, Suri RM, Schaff HV, Enriquez-Sarano M. Comprehensive Imaging in Women With Organic Mitral Regurgitation: Implications for Clinical Outcome.. JACC Cardiovasc Imaging 2016; 9(4):388-96.
Capoulade R, Le Ven F, Clavel MA, Dumesnil JG, Dahou A, Thébault C, Arsenault M, O'Connor K, Bédard É, Beaudoin J, Sénéchal M, Bernier M, Pibarot P. Echocardiographic predictors of outcomes in adults with aortic stenosis.. Heart 2016; 102(12):934-42.
Clavel MA. How Does CT Fit Into the Evaluation and Management of Patients With AS?. J Am Coll Cardiol 2017; 0(0):Epub.
Berthelot-Richer M, Pibarot P, Capoulade R, Dumesnil JG, Dahou A, Le Ven F, Thebault C, Clavel MA. Discordant Grading of Aortic Stenosis Severity: Echocardiographic Predictors of Survival Benefit from Aortic Valve Replacement.. JACC Cardiovasc Imaging 2016; 9(7):797-805.
Tastet L, Simard L, Clavel MA. Severe and Asymptomatic Aortic Stenosis Management Challenge: Knowing That We Do Not Really Know.. Curr Treat Options Cardiovasc Med 2017; 19(5):33.
Simard L, Côté N, Mathieu P, Clavel MA. Response by Simard et al to Letter Regarding Article, "Sex-Related Discordance Between Aortic Valve Calcification and Hemodynamic Severity of Aortic Stenosis: Is Valvular Fibrosis the Explanation?". Circ Res 2017; 120(5):e26.
Clavel MA, Burwash IG, Pibarot P. Cardiac Imaging for Assessing Low-Gradient Severe Aortic Stenosis.. JACC Cardiovasc Imaging 2017; 10(2):185-202.
Côté N, Pibarot P, Clavel MA. Incidence, risk factors, clinical impact, and management of bioprosthesis structural valve degeneration.. Curr Opin Cardiol 2017; 32(2):123-129.
Yanagawa B, Mazine A, Bhatt DL, Clavel MA, Côté N, Cheema AN, Pibarot P, Verma S. Subclinical bioprosthetic aortic valve thrombosis: clinical and translational implications.. Curr Opin Cardiol 2017; 32(2):137-146.
Clavel MA, Côté N, Pibarot P. Dilemma in the therapeutic management of low-gradient aortic stenosis.. Curr Opin Cardiol 2017; 32(2):147-151.
Lazam S, Vanoverschelde JL, Tribouilloy C, Grigioni F, Suri RM, Avierinos JF, de Meester C, Barbieri A, Rusinaru D, Russo A, Pasquet A, Michelena HI, Huebner M, Maalouf J, Clavel MA, Szymanski C, Enriquez-Sarano M. Twenty-Year Outcome After Mitral Repair Versus Replacement for Severe Degenerative Mitral Regurgitation: Analysis of a Large, Prospective, Multicenter, International Registry.. Circulation 2017; 135(5):410-422.
Michelena HI, Suri RM, Katan O, Eleid MF, Clavel MA, Maurer MJ, Pellikka PA, Mahoney D, Enriquez-Sarano M. Sex Differences and Survival in Adults With Bicuspid Aortic Valves: Verification in 3 Contemporary Echocardiographic Cohorts.. J Am Heart Assoc 2016; 5(10):e004211.
Clavel MA. Echocardiographic Assessment of Aortic Stenosis Severity: Do Not Rely on a Single Parameter.. J Am Heart Assoc 2016; 5(10):e004680.
Clavel MA, Tribouilloy C, Vanoverschelde JL, Pizarro R, Suri RM, Szymanski C, Lazam S, Oberti P, Michelena HI, Jaffe A, Enriquez-Sarano M. Association of B-Type Natriuretic Peptide With Survival in Patients With Degenerative Mitral Regurgitation.. J Am Coll Cardiol 2016; 68(12):1297-307.
Mohamed N, Mahmut A, Boulanger MC, Arsenault BJ, Bouchareb R, Simard S, Witztum JL, Clavel MA, Pibarot P, Bossé Y, Tsimikas S, Mathieu P. Autotaxin interacts with lipoprotein(a) and oxidized phospholipids in predicting the risk of calcific aortic valve stenosis in patients with coronary artery disease.. J Int Med Res 2016; 280(5):509-17.
Lindman BR, Clavel MA, Mathieu P, Iung B, Lancelloti P, Otto CM, Pibarot P. Calcific aortic stenosis.. Nat Rev Dis Primers 2016; 2(0):1-28.
Dahou A, Toubal O, Clavel MA, Beaudoin J, Magne J, Mathieu P, Philippon F, Dumesnil JG, Puri R, Ribeiro HB, Larose É, Rodés-Cabau J, Pibarot P. Relationship Between QT Interval and Outcome in Low-Flow Low-Gradient Aortic Stenosis With Low Left Ventricular Ejection Fraction.. J Am Heart Assoc 2016; 5(10):e003980.
Pibarot P, Clavel MA. Doppler Echocardiographic Quantitation of Aortic Valve Stenosis: A Science in Constant Evolution.. J Am Soc Echocardiogr 2016; 29(10):1019-1022.
Ribeiro HB, Orwat S, Hayek SS, Larose É, Babaliaros V, Dahou A, Le Ven F, Pasian S, Puri R, Abdul-Jawad Altisent O, Campelo-Parada F, Clavel MA, Pibarot P, Lerakis S, Baumgartner H, Rodés-Cabau J. Cardiovascular Magnetic Resonance to Evaluate Aortic Regurgitation After Transcatheter Aortic Valve Replacement.. J Am Coll Cardiol 2016; 68(6):577-85.
Dayan V, Vignolo G, Magne J, Clavel MA, Mohty D, Pibarot P. Reply: Inconsistency of Hemodynamic Data in Low-Gradient Severe Aortic Stenosis: Paradoxical Low-Gradient Aortic Stenosis: The HFpEF of Aortic Stenosis.. J Am Coll Cardiol 2016; 67(20):2448-9.
Clavel MA, Magne J, Pibarot P. Low-gradient aortic stenosis.. Eur Heart J 2016; 37(34):2645-57.
Unger P, Clavel MA, Lindman BR, Mathieu P, Pibarot P. Pathophysiology and management of multivalvular disease.. Nat Rev Cardiol 2016; 13(7):429-40.
Capoulade R, Clavel MA, Le Ven F, Dahou A, Thébault C, Tastet L, Shen M, Arsenault M, Bédard É, Beaudoin J, O'Connor K, Bernier M, Dumesnil JG, Pibarot P. Impact of left ventricular remodelling patterns on outcomes in patients with aortic stenosis.. Eur Heart J Cardiovasc Imaging 2017; 18(1):1378-87.
Shen M, Tastet L, Capoulade R, Larose É, Bédard É, Arsenault M, Chetaille P, Dumesnil JG, Mathieu P, Clavel MA, Pibarot P. Effect of age and aortic valve anatomy on calcification and haemodynamic severity of aortic stenosis.. Heart 2017; 103(1):32-39.
Dahou A, Clavel MA, Dumesnil JG, Capoulade R, Ribeiro HB, O'Connor K, Mathieu P, Beaudoin J, Larose É, Rodés-Cabau J, Pibarot P. Impact of AVR on LV Remodeling and Function in Paradoxical Low-Flow, Low-Gradient Aortic Stenosis With Preserved LVEF.. JACC Cardiovasc Imaging 2017; 10(1):88-89.
Simard L, Côté N, Dagenais F, Mathieu P, Couture C, Trahan S, Bossé Y, Mohammadi S, Pagé S, Joubert P, Clavel MA. Sex-Related Discordance Between Aortic Valve Calcification and Hemodynamic Severity of Aortic Stenosis: Is Valvular Fibrosis the Explanation?. Circ Res 2017; 120(4):681-691.
Clavel MA. How Does CT Fit Into the Evaluation and Management of Patients With AS?. J Am Coll Cardiol 2016; 0(0):Epub.
Simard L, Perron J, Shen M, Tastet L, Mohammadi S, Clisson M, Poulin A, Clavel MA. Vascular Burden Impact on Echocardiographic Valvular Graft Degeneration Following a Ross Procedure in Young Adults.. J Am Coll Cardiol 2017; 70(8):1099-1101.
Côté N, Simard L, Zenses AS, Tastet L, Shen M, Clisson M, Clavel MA. Impact of Vascular Hemodynamics on Aortic Stenosis Evaluation: New Insights Into the Pathophysiology of Normal Flow-Small Aortic Valve Area-Low Gradient Pattern.. J Am Heart Assoc 2017; 6(7):e006276.
Clavel MA, Iung B, Pibarot P. A nationwide contemporary epidemiological portrait of valvular heart diseases.. Heart 2017; 103(21):1660-2.
Clavel MA. Therapeutic Management of Low-Gradient Aortic Stenosis: First Assess the State of the Schrödinger Cat Before Making a Decision.. Circ Cardiovasc Interv 2017; 10(5):e005320.
van Gils L, Clavel MA, Vollema EM, Hahn RT, Spitzer E, Delgado V, Nazif T, De Jaegere PP, Geleijnse ML, Ben-Yehuda O, Bax JJ, Leon MB, Pibarot P, Van Mieghem NM. Prognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction.. J Am Coll Cardiol 2017; 69(19):2383-2392.
Dahou A, Clavel MA, Capoulade R, O'Connor K, Ribeiro HB, Côté N, Le Ven F, Rodés-Cabau J, Dumesnil JG, Mathieu P, Pibarot P. B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin for Risk Stratification in Low-Flow, Low-Gradient Aortic Stenosis: A Substudy of the TOPAS Study.. JACC Cardiovasc Imaging 2018; 11(7):939-947.
Tastet L, Enriquez-Sarano M, Capoulade R, Malouf J, Araoz PA, Shen M, Michelena HI, Larose E, Arsenault M, Bédard É, Pibarot P, Clavel MA. Impact of Aortic Valve Calcification and Sex on Hemodynamic Progression and Clinical Outcomes in AS.. J Am Coll Cardiol 2017; 69(16):2096-2098.
Benfari G, Clavel MA, Nistri S, Maffeis C, Vassanelli C, Enriquez-Sarano M, Rossi A. Concomitant mitral regurgitation and aortic stenosis: one step further to low-flow preserved ejection fraction aortic stenosis.. Eur Heart J Cardiovasc Imaging 2018; 19(5):569-573.
Pibarot P, Clavel MA. Preload Stress Echocardiography: A New Tool to Confirm Severity of Low-Gradient Aortic Stenosis.. Circ Cardiovasc Imaging 2017; 10(10):e007035.
Grigioni F, Clavel MA, Vanoverschelde JL, Tribouilloy C, Pizarro R, Huebner M, Avierinos JF, Barbieri A, Suri R, Pasquet A, Rusinaru D, Gargiulo GD, Oberti P, Théron A, Bursi F, Michelena H, Lazam S, Szymanski C, Nkomo VT, Schumacher M, Bacchi-Reggiani L, Enriquez-Sarano M. The MIDA Mortality Risk Score: development and external validation of a prognostic model for early and late death in degenerative mitral regurgitation.. Eur Heart J 2018; 39(15):1281-91.
Bäck M, Pizarro R, Clavel MA. Biomarkers in Mitral Regurgitation.. Prog Cardiovasc Dis 2017; 60(3):334-341.
Dupuis M, Mahjoub H, Clavel MA, Côté N, Toubal O, Tastet L, Dumesnil JG, O'Connor K, Dahou A, Thébault C, Bélanger C, Beaudoin J, Arsenault M, Bernier M, Pibarot P. Forward Left Ventricular Ejection Fraction: A Simple Risk Marker in Patients With Primary Mitral Regurgitation.. J Am Heart Assoc 2017; 6(11):e006309.
Shen M, Tastet L, Bergler-Klein J, Pibarot P, Clavel MA. Blood, tissue and imaging biomarkers in calcific aortic valve stenosis: past, present and future.. Curr Opin Cardiol 2018; 33(2):125-133.
Pibarot P, Clavel MA. Outcome of aortic valve replacement in aortic stenosis: the number of valve cusps matters.. Eur Heart J Cardiovasc Imaging 2018; 19(1):9-11.
Clemenceau A, Bérubé JC, Bélanger P, Gaudreault N, Lamontagne M, Toubal O, Clavel MA, Capoulade R, Mathieu P, Pibarot P, Bosse Y. Deleterious variants in DCHS1 are prevalent in sporadic cases of mitral valve prolapse.. Mol Genet Genomic Med 2018; 6(1):114-120.
Lindman BR, Clavel MA, Abu-Alhayja'a R, Côté N, Dagenais F, Novak E, Voisine P, Poulin A, Arsenault BJ, Desmeules P, Dahou A, Taster L, Aldahoun K, Bossé Y, Mathieu P, Pibarot P. Multimarker Approach to Identify Patients With Higher Mortality and Rehospitalization Rate After Surgical Aortic Valve Replacement for Aortic Stenosis.. JACC Cardiovasc Interv 2018; 11(21):2172-2181.
Annabi MS, Touboul E, Dahou A, Burwash IG, Bergler-Klein J, Enriquez-Sarano M, Orwat S, Baumgartner H, Mascherbauer J, Mundigler G, Cavalcante JL, Larose E, Pibarot P, Clavel MA. Dobutamine Stress Echocardiography for Management of Low-Flow, Low-Gradient Aortic Stenosis.. J Am Coll Cardiol 2018; 71(5):475-485.
Ong G, Clavel MA, Pibarot P. Concomitant mitral regurgitation: an insidious cause of lowflow, low-gradient severe aortic stenosis.. EuroIntervention 2018; 13(14):1622-1625.
Nsaibia MJ, Boulanger MC, Bouchareb R, Mkannez G, Dahou A, Salaun E, Bossé Y, Clavel MA, Arsenault BJ, Pibarot P, Mathieu P. Soluble CD14 is associated with the structural failure of bioprostheses.. Clin Chim Acta 2018; 485(0):173-177.
Pawade T, Clavel MA, Tribouilloy C, Dreyfus J, Mathieu T, Tastet L, Renard C, Gun M, Jenkins WSA, Macron L, Sechrist JW, Lacomis JM, Nguyen V, Galian Gay L, Cuéllar Calabria H, Ntalas I, Cartlidge TRG, Prendergast B, Rajani R, Evangelista A, Cavalcante JL, Newby DE, Pibarot P, Messika Zeitoun D, Dweck MR. Computed Tomography Aortic Valve Calcium Scoring in Patients With Aortic Stenosis.. Circ Cardiovasc Imaging 2018; 11(3):e007146.
Thériault S, Gaudreault N, Lamontagne M, Rosa M, Boulanger MC, Messika-Zeitoun D, Clavel MA, Capoulade R, Dagenais F, Pibarot P, Mathieu P, Bossé Y. A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis.. Nat Commun 2018; 9(1):988.
Toubal O, Mahjoub H, Thébault C, Clavel MA, Dahou A, Magne J, O'Connor K, Beaudoin J, Bernier M, Le Ven F, Pibarot P. Increasing Pulmonary Arterial Pressure at Low Level of Exercise in Asymptomatic, Organic Mitral Regurgitation.. J Am Coll Cardiol 2018; 71(6):700-701.
Tastet L, Capoulade R, Shen M, Clavel MA, Côté N, Mathieu P, Arsenault M, Bédard É, Tremblay A, Samson M, Bossé Y, Dumesnil JG, Arsenault BJ, Beaudoin J, Bernier M, Després JP, Pibarot P. ApoB/ApoA-I Ratio is Associated With Faster Hemodynamic Progression of Aortic Stenosis: Results From the PROGRESSA (Metabolic Determinants of the Progression of Aortic Stenosis) Study.. J Am Heart Assoc 2018; 7(4):e007980.
Alassas K, Mohty D, Clavel MA, Husain A, Hijji T, Aljoufan M, Alhalees Z, Fadel BM. Transcatheter versus surgical valve replacement for a failed pulmonary homograft in the Ross population.. J Thorac Cardiovasc Surg 2018; 155(4):1434-1444.
Benfari G, Nistri S, Faggiano P, Clavel MA, Maffeis C, Enriquez-Sarano M, Vassanelli C, Rossi A. Mitral Effective Regurgitant Orifice Area Predicts Pulmonary Artery Pressure Level in Patients with Aortic Valve Stenosis.. J Am Soc Echocardiogr 2018; 31(5):570-7.e1.
Dziadzko V, Clavel MA, Dziadzko M, Medina-Inojosa JR, Michelena H, Maalouf J, Nkomo V, Thapa P, Enriquez-Sarano M. Outcome and undertreatment of mitral regurgitation: a community cohort study.. Lancet 2018; 391(10124):960-969.
Ribeiro HB, Lerakis S, Gilard M, Cavalcante JL, Makkar R, Herrmann HC, Windecker S, Enriquez-Sarano M, Cheema AN, Nombela-Franco L, Amat-Santos I, Muñoz-García AJ, Garcia Del Blanco B, Zajarias A, Lisko JC, Hayek S, Babaliaros V, Le Ven F, Gleason TG, Chakravarty T, Szeto WY, Clavel MA, de Agustin A, Serra V, Schindler JT, Dahou A, Puri R, Pelletier-Beaumont E, Côté M, Pibarot P, Rodés-Cabau J. Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis: The TOPAS-TAVI Registry.. J Am Coll Cardiol 2018; 71(12):1297-1308.
Zenses AS, Evin MA, Stanová V, Clavel MA, Barragan P, Rodés-Cabau J, Obadia JF, Pibarot P, Rieu R. Effect of size and position of self-expanding transcatheter valve on haemodynamics following valve-in-valve procedure in small surgical bioprostheses: an in vitro study.. EuroIntervention 2018; 14(3):e282-e289.
Côté N, Pibarot P, Clavel MA. Aortic stenosis: what is the role of aging processes?. Aging (Albany NY) 2019; 11(4):1085-1086.
Salaun E, Mahjoub H, Girerd N, Dagenais F, Voisine P, Mohammadi S, Yanagawa B, Kalavrouziotis D, Juni P, Verma S, Puri R, Coté N, Rodés-Cabau J, Mathieu P, Clavel MA, Pibarot P.. Rate, Timing, Correlates, and Outcomes of Hemodynamic Valve Deterioration After Bioprosthetic Surgical Aortic Valve Replacement.. Circulation 2018; 138(10):971-985.
Everett RJ, Tastet L, Clavel MA, Chin CWL, Capoulade R, Vassiliou VS, Kwiecinski J, Gomez M, van Beek EJR, White AC, Prasad SK, Larose E, Tuck C, Semple S, Newby DE, Pibarot P, Dweck MR. Progression of Hypertrophy and Myocardial Fibrosis in Aortic Stenosis: A Multicenter Cardiac Magnetic Resonance Study.. Circ Cardiovasc Imaging 2018; 11(6):e007451.
Salaun E, Zenses AS, Clavel MA, Rodriguez-Gabella T, Dumont E, Mohammadi S, Doyle D, Paradis JM, De Larochelliere R, Pibarot P, Rodés-Cabau J. Valve-in-Valve Procedure in Failed Transcatheter Aortic Valves.. JACC Cardiovasc Imaging 2019; 12(1):198-202.
Salaun E, Mahjoub H, Dahou A, Mathieu P, Larose E, Després JP, Rodés-Cabau J, Arsenault BJ, Puri R, Clavel MA, Pibarot P. Hemodynamic Deterioration of Surgically Implanted Bioprosthetic Aortic Valves.. J Am Coll Cardiol 2018; 72(3):241-251.
Everett RJ, Clavel MA, Pibarot P, Dweck MR. Timing of intervention in aortic stenosis: a review of current and future strategies.. Heart 2018; 104(24):2067-2076.
Zenses AS, Dahou A, Salaun E, Clavel MA, Rodés-Cabau J, Ong G, Guzzetti E, Côté M, De Larochellière R, Paradis JM, Doyle D, Mohammadi S, Dumont É, Chamandi C, Rodriguez-Gabella T, Rieu R, Pibarot P. Haemodynamic outcomes following aortic valve-in-valve procedure.. Open Heart 2018; 5(2):e000854.
Vollema EM, Sugimoto T, Shen M, Tastet L, Ng ACT, Abou R, Marsan NA, Mertens B, Dulgheru R, Lancellotti P, Clavel MA, Pibarot P, Genereux P, Leon MB, Delgado V, Bax JJ. Association of Left Ventricular Global Longitudinal Strain With Asymptomatic Severe Aortic Stenosis: Natural Course and Prognostic Value.. JAMA Cardiol 2018; 3(9):839-847.
Salaun E, Clavel MA, Rodés-Cabau J, Pibarot P.. Bioprosthetic aortic valve durability in the era of transcatheter aortic valve implantation.. Heart 2018; 104(16):1323-1332.
Annabi MS, Clisson M, Clavel MA, Pibarot P.. Workup and Management of Patients With Paradoxical Low-Flow, Low-Gradient Aortic Stenosis.. Curr Treat Options Cardiovasc Med 2018; 20(6):49.
Alkurashi AK, Thaden JJ, Naser JA, El-Am EA, Pislaru SV, Greason KL, Negrotto SM, Clavel MA, Pellikka PA, Maleszewski JJ, Nkomo VT. Underestimation of Aortic Stenosis Severity by Doppler Mean Gradient during Atrial Fibrillation: Insights from Aortic Valve Weight.. J Am Soc Echocardiogr 2023; 36(1):53-59.
Dehghani P, Singer Z, Morrison J, Booker J, Lavoie A, Zimmermann R, Basran P, Webb JG, Cheema AN, Pibarot P, Clavel MA.. Characteristics and Usefulness of Unintended Premature Ventricular Contraction During Invasive Assessment of Aortic Stenosis.. Int J Cardiol 2020; 313(0):35-38.
Pibarot P, Borger MA, Clavel MA, Griffith B, Bavaria JE, Svensson LG, Thourani VH. Study Design of the Prospective Non-Randomized Single-Arm Multicenter Evaluation of the Durability of Aortic Bioprosthetic Valves with RESILIA Tissue in Subjects under 65 Years Old (RESILIENCE Trial).. Struct Heart 2020; 4(1):46-52.
Arutyunyan V, Chernov I, Komarov R, Sinelnikov Y,Kadyraliev B, Enginoev S, Tcheglov M, Ismailbaev A, Baranov A, Ashurov F, Clavel MA, Pibarot P, Pompeu M, Sá O, Weymann A, Zhigalov K.. Immediate Outcomes of Aortic Valve Neocuspidization With Glutaraldehyde-treated Autologous Pericardium: A Multicenter Study.. Braz J Cardiovasc Surg 2020; 35(3):241-248.
Guzzetti E, Clavel MA, Pibarot P.. Usefulness of the Energy Loss Index in the Adjudication of Low-Gradient Aortic Stenosis Severity.. Eur Heart J Cardiovasc Imaging 2020; 21(6):616-618.
Shen M, Capoulade R, Tastet L, Guzzetti E, Clavel MA, Salaun E, Bédard É, Arsenault M, Chetaille P, Tizón-Marcos H, Le Ven F, Pibarot P, Larose E.. Prevalence of left ventricle non-compaction criteria in adult patients with bicuspid aortic valve versus healthy control subjects.. Open Heart 2018; 5(2):e000869.
Guzzetti E, Annabi MS, Ong G, Zenses AS, Dagenais F, Tastet L, Salaun E, Shen M, Piché ME, Poirier P, Voisine P, Pibarot P, Clavel MA. Impact of Metabolic Syndrome and/or Diabetes Mellitus on Left Ventricular Mass and Remodeling in Patients With Aortic Stenosis Before and After Aortic Valve Replacement.. Am J Cardiol 2019; 123(1):123-131.
Delgado V, Clavel MA, Hahn RT, Gillam L, Bax J, Sengupta PP, Pibarot P. How Do We Reconcile Echocardiography, Computed Tomography, and Hybrid Imaging in Assessing Discordant Grading of Aortic Stenosis Severity?. JACC Cardiovasc Imaging 2019; 12(2):267-282.
Pibarot P, Clavel MA. Prosthesis-Patient Mismatch After Transcatheter Aortic Valve Replacement: It Is Neither Rare Nor Benign.. J Am Coll Cardiol 2018; 72(22):2712-2716.
Lancellotti P, Magne J, Dulgheru R, Clavel MA, Donal E, Vannan MA, Chambers J, Rosenhek R, Habib G, Lloyd G, Nistri S, Garbi M, Marchetta S, Fattouch K, Coisne A, Montaigne D, Modine T, Davin L, Gach O, Radermecker M, Liu S, Gillam L, Rossi A, Galli E, Ilardi F, Tastet L, Capoulade R, Zilberszac R, Vollema EM, Delgado V, Cosyns B, Lafitte S, Bernard A, Pierard LA, Bax JJ, Pibarot P, Oury C. Outcomes of Patients With Asymptomatic Aortic Stenosis Followed Up in Heart Valve Clinics.. JAMA Cardiol 2018; 3(11):1060-1068.
Ong G, Annabi MS, Clavel MA, Guzzetti E, Salaun E, Toubal O, Dahou A, Pibarot P. Paravalvular Regurgitation After Transcatheter Aortic Valve Replacement: Is the Problem Solved?. Interv Cardiol Clin 2018; 7(4):445-458.
Hourdain J, Clavel MA, Deharo JC, Asirvatham S, Avierinos JF, Habib G, Franceschi F, Probst V, Sadoul N, Martins R, Leclercq C, Chauvin M, Pasquie JL, Maury P, Laurent G, Ackerman M, Hodge DO, Enriquez-Sarano M. Common Phenotype in Patients With Mitral Valve Prolapse Who Experienced Sudden Cardiac Death.. Circulation 2018; 138(10):1067-1069.
Chau KH, Douglas PS, Pibarot P, Hahn RT, Khalique OK, Jaber WA, Cremer P, Weissman NJ, Asch FM, Zhang Y, Gertz ZM, Elmariah S, Clavel MA, Thourani VH, Daubert M, Alu MC, Leon MB, Lindman BR. Regression of Left Ventricular Mass After Transcatheter Aortic Valve Replacement: The PARTNER Trials and Registries.. J Am Coll Cardiol 2020; 75(19):2446-2458.
Zhang B, Xu H, Zhang H, Liu Q, Ye Y, Hao J, Zhao Q, Qi X, Liu S, Zhang E, Xu Y, Gao R, Pibarot P, Clavel MA, Wu Y; CHINA-DVD Collaborators.. Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide in Elderly Patients With Valvular Heart Disease.. J Am Coll Cardiol 2020; 75(14):1659-1672.
Sá MPBO, Carvalho MMB, Sobral Filho DC, Cavalcanti LRP, Diniz RGS, Rayol SC, Soares AMMN, Sá FBCA, Menezes AM, Clavel MA, Pibarot P, Lima RC. Impact of surgical aortic root enlargement on the outcomes of aortic valve replacement: a meta-analysis of 13,174 patients.. Interact Cardiovasc Thorac Surg 2019; 29(1):74-82.
Sá MPBO, de Carvalho MMB, Sobral Filho DC, Cavalcanti LRP, Rayol SDC, Diniz RGS, Menezes AM, Clavel MA, Pibarot P, Lima RC. Surgical aortic valve replacement and patient-prosthesis mismatch: a meta-analysis of 108?182 patients.. Eur J Cardiothorac Surg 2019; 56(1):44-54.
Bartko PE, Clavel MA, Annabi MS, Dahou A, Ristl R, Goliasch G, Baumgartner H, Hengstenberg C, Cavalcante JL, Burwash I, Enriquez-Sarano M, Bergler-Klein J, Rodés-Cabau J, Pibarot P, Mascherbauer J. Sex-Related Differences in Low-Gradient, Low-Ejection Fraction Aortic Stenosis: Results From the Multicenter TOPAS Study.. JACC Cardiovasc Imaging 2019; 12(1):203-205.
Maes F, Lerakis S, Barbosa Ribeiro H, Gilard M, Cavalcante JL, Makkar R, Herrmann HC, Windecker S, Enriquez-Sarano M, Cheema AN, Nombela-Franco L, Amat-Santos I, Muñoz-García AJ, Garcia Del Blanco B, Zajarias A, Lisko JC, Hayek S, Babaliaros V, Le Ven F, Gleason TG, Chakravarty T, Szeto W, Clavel MA, de Agustin A, Serra V, Schindler JT, Dahou A, Salah-Annabi M, Pelletier-Beaumont E, Côté M, Puri R, Pibarot P, Rodés-Cabau J. Outcomes From Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis and Left Ventricular Ejection Fraction Less Than 30%: A Substudy From the TOPAS-TAVI Registry.. JAMA Cardiol 2019; 4(1):64-70.
Salaun E, Côté N, Clavel MA, Pibarot P. Biomarkers of aortic bioprosthetic valve structural degeneration.. Curr Opin Cardiol 2019; 34(2):132-139.
Gertz ZM, Pibarot P, Douglas PS, Elmariah S, Alu MC, McAndrew T, Zhang Y, Hodson RW, Hahn RT, Weissman NJ, Lindman BR, Clavel MA, Lerakis S, Abbas AE, Thourani VH, Kodali S, Kapadia S, Suri RM, Makkar R, Mack M, Leon MB, Herrmann HC. Implications of Left Ventricular Geometry in Low-Flow Aortic Stenosis: A PARTNER 2 Trial Subanalysis.. JACC Cardiovasc Imaging 2019; 12(2):367-368.
Bing R, Cavalcante JL, Everett RJ, Clavel MA, Newby DE, Dweck MR. Imaging and Impact of Myocardial Fibrosis in Aortic Stenosis.. JACC Cardiovasc Imaging 2019; 12(2):283-296.
Doris MK, Everett RJ, Shun-Shin M, Clavel MA, Dweck MR. The Role of Imaging in Measuring Disease Progression and Assessing Novel Therapies in Aortic Stenosis.. JACC Cardiovasc Imaging 2019; 12(1):185-197.
Grigioni F, Benfari G, Vanoverschelde JL, Tribouilloy C, Avierinos JF, Bursi F, Suri RM, Guerra F, Pasquet A, Rusinaru D, Marcelli E, Théron A, Barbieri A, Michelena H, Lazam S, Szymanski C, Nkomo VT, Capucci A, Thapa P, Enriquez-Sarano M; MIDA Investigators (Clavel MA parmi les 45 collaborateurs). Long-Term Implications of Atrial Fibrillation in Patients With Degenerative Mitral Regurgitation.. J Am Coll Cardiol 2019; 73(3):264-274.
Capoulade R, Clavel MA, Dumesnil JG, Chan KL, Teo KK, Tam JW, Côté N, Mathieu P, Després JP, Pibarot P. Insulin Resistance and LVH Progression in Patients With Calcific Aortic Stenosis: A Substudy of the ASTRONOMER Trial.. JACC Cardiovasc Imaging 2013; 6(2):165-74.
Clavel MA, Dumesnil JG, Capoulade R, Mathieu P, Sénéchal M, Pibarot P. Outcome of Patients with Aortic Stenosis, Small Valve Area and Low-Flow, Low-Gradient despite Preserved Left Ventricular Ejection Fraction - Reply.. J Am Coll Cardiol 2013; 61(17):1833-4.
Bartko PE, Heinze G, Graf S, Clavel MA, Khorsand A, Bergler-Klein J, Burwash IG, Dumesnil JG, Sénéchal M, Baumgartner H, Rosenhek R, Pibarot P, Mundigler G. Two-Dimensional Strain for the Assessment of Left Ventricular Function in Low Flow-Low Gradient Aortic Stenosis, Relationship to Hemodynamics, and Outcome: A Substudy of the Multicenter TOPAS Study.. Circ Cardiovasc Imaging 2013; 6(2):268-76.
Clavel MA, Messika-Zeitoun D, Pibarot P, Aggarval S, Malouf J, Araoz P, Michelina H, Cueff C, Larose É, Capoulade R, Vahanian A, Enriquez-Sarano M. The complex nature of discordant aortic stenosis severity grading: New insights from combined Doppler-Echocardiographic and computed tomography study.. J Am Coll Cardiol 2013; 62(24):2329-38.
Capoulade R, Clavel MA, Mathieu P, Côté N, Dumesnil JG, Arsenault M, Bédard E, Pibarot P. Impact of hypertension and renin angiotensin system inhibitors in aprtic stenosis.. Eur J Clin Invest 2013; 43(12):1262-72.
Le Ven F, Freeman M, Webb J, Clavel MA, Wheeler M, Dumont E, Thompson C, De Larochellière R, Moss R, Doyle D, Ribeiro HB, Alcazar MU, Nombela-Franco L, Rodés-Cabau J, Pibarot P.. Impact of Low Flow on the Outcome of High Risk Patients Undergoing Transcatheter Aortic Valve Replacement.. J Am Coll Cardiol 2013; 62(9):782-8.
Katsanos S, Yiu KH, Clavel MA, Rodés-Cabau J, Leong D, van der Kley F, Ajmone Marsan N, Bax JJ, Pibarot P, Delgado V.. Impact of Valvuloarterial Impedance on 2-Year Outcome of Patients Undergoing Transcatheter Aortic Valve Implantation.. J Am Soc Echocardiogr 2013; 26(7):691-8.
Clavel MA, Ennezat PV, Maréchaux S, Dumesnil JG, Capoulade R, Hachicha Z, Mathieu P, Bellouin A, Bergeron S, Meimoun P, Arsenault M, Le Tourneau T, Pasquet A, Couture C, Pibarot P. Stress Echocardiography to Assess Stenosis Severity and Predict Outcome in Patients With Paradoxical Low-Flow, Low-Gradient Aortic Stenosis and Preserved LVEF.. JACC Cardiovasc Imaging 2013; 6(2):175-83.
Aggarwal SR, Clavel MA, Messika-Zeitoun D, Cueff C, Malouf J, Araoz PA, Mankad R, Michelena H, Vahanian A, Enriquez-Sarano M.. Sex differences in aortic valve calcification measured by multidetector computed tomography in aortic stenosis.. Circ Cardiovasc Imaging 2013; 6(1):40-7.
Capoulade R, Clavel MA, Dumesnil JG, Chan KL, Teo KK, Tam JW, Côté N, Mathieu P, Després JP, Pibarot P. Impact of metabolic syndrome on progression of aortic stenosis: influence of age and statin therapy.. J Am Coll Cardiol 2012; 60(3):216-23.
Clavel MA, Dumesnil JG, Capoulade R, Mathieu P, Sénéchal M, Pibarot P. Outcome of patients with aortic stenosis, small valve area, and low-flow, low-gradient despite preserved left ventricular ejection fraction.. J Am Coll Cardiol 2012; 60(14):1259-67.
Bagur R, Rodés-Cabau J, Dumont E, De Larochellière R, Doyle D, Pibarot P, Côté M, Clavel MA, Villeneuve J, Gutiérrez M, Poirier P, Bertrand OF. Performance-based functional assessment of patients undergoing transcatheter aortic valve implantation.. Am Heart J 2011; 161(4):726-34.
Garcia J, Kadem L, Larose E, Clavel MA, Pibarot P. Comparison between Cardiovascular Magnetic Resonance and Transthoracic Doppler Echocardiography for the Estimation of Effective Orifice Area in Aortic Stenosis.. J Cardiovasc Magn Reson 2011; 13(1):25.
Clavel MA, Rodés-Cabau J, Dumont É, Bagur R, Bergeron S, De Larochellière R, Doyle D, Larose E, Dumesnil JG, Pibarot P. Validation and characterization of transcatheter aortic valve effective orifice area measured by Doppler echocardiography.. JACC Cardiovasc Imaging 2011; 4(10):1053-62.
Bagur R, Webb JG, Nietlispach F, Dumont E, De Larochellière R, Doyle D, Masson JB, Gutiérrez MJ, Clavel MA, Bertrand OF, Pibarot P, Rodés-Cabau J. Acute kidney injury following transcatheter aortic valve implantation: predictive factors, prognostic value, and comparison with surgical aortic valve replacement.. Eur Heart J 2010; 31(7):865-74.
Clavel MA, Burwash IG, Mundigler G, Dumesnil JG, Baumgartner H, Bergler-Klein J, Sénéchal M, Mathieu P, Couture C, Beanlands R, Pibarot P. Validation of conventional and simplified methods to calculate projected valve area at normal flow rate in patients with low flow, low gradient aortic stenosis: the multicenter TOPAS (True or Pseudo Severe Aortic Stenosis) study.. J Am Soc Echocardiogr 2010; 23(4):380-6.
Pagé A, Dumesnil JG, Clavel MA, Chan KL, Teo KK, Tam JW, Mathieu P, Després JP, Pibarot P, . Metabolic syndrome is associated with more pronounced impairment of left ventricle geometry and function in patients with calcific aortic stenosis: a substudy of the ASTRONOMER (Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin).. J Am Coll Cardiol 2010; 55(17):1867-74.
Clavel MA, Webb JG, Rodés-Cabau J, Masson JB, Dumont E, De Larochellière R, Doyle D, Bergeron S, Baumgartner H, Burwash IG, Dumesnil JG, Mundigler G, Moss R, Kempny A, Bagur R, Bergler-Klein J, Gurvitch R, Mathieu P, Pibarot P. Comparison between transcatheter and surgical prosthetic valve implantation in patients with severe aortic stenosis and reduced left ventricular ejection fraction.. Circulation 2010; 122(19):1928-36.
Gaillard E, Kadem L, Clavel MA, Pibarot P, Durand LG. Optimization of Doppler echocardiographic velocity measurements using an automatic contour detection method.. Ultrasound Med Biol 2010; 36(9):1513-24.
Guidoin R, Douville Y, Clavel MA, Zhang Z, Nutley M, Pîbarot P, Dionne G. The marvel of percutaneous cardiovascular devices in the elderly.. Ann N Y Acad Sci 2010; 1197(0):188-99.
Pibarot P, Dumesnil JG, Clavel MA. Clinical vignette: paradoxical low flow, low gradient aortic stenosis despite preserved LV ejection fraction.. Arch Cardiovasc Dis 2008; 101(9):595-6.
Rodés-Cabau J, Dumont E, De Larochellière R, Doyle D, Lemieux J, Bergeron S, Clavel MA, Villeneuve J, Raby K, Bertrand OF, Pibarot P. Feasibility and initial results of percutaneous aortic valve implantation including selection of the transfemoral or transapical approach in patients with severe aortic stenosis.. Am J Cardiol 2008; 102(9):1240-6.
Clavel MA, Fuchs C, Burwash IG, Mundigler G, Dumesnil JG, Baumgartner H, Bergler-Klein J, Beanlands RS, Mathieu P, Magne J, Pibarot P. Predictors of outcomes in low-flow, low-gradient aortic stenosis: results of the multicenter TOPAS Study.. Circulation 2008; 118(14):S234-42.
Rodés-Cabau J, Dumont E, Miró S, Doyle D, De Larochellière R, Clavel MA, Villeneuve J, Bergeron S, Senechal M, Pibarot P.. Apical aortic valve implantation in a patient with a mechanical valve prosthesis in mitral position.. Circ Cardiovasc Interv 2008; 1(3):233.
Clavel MA, Dumont E, Pibarot P, Doyle D, De Larochellière R, Villeneuve J, Bergeron S, Couture C, Rodés-Cabau J. Severe valvular regurgitation and late prosthesis embolization after percutaneous aortic valve implantation.. Ann Thorac Surg 2009; 87(2):618-21.
Gutiérrez M, Rodés-Cabau J, Bagur R, Doyle D, DeLarochellière R, Bergeron S, Lemieux J, Villeneuve J, Côté M, Bertrand OF, Poirier P, Clavel MA, Pibarot P, Dumont E.. Electrocardiographic changes and clinical outcomes after transapical aortic valve implantation.. Am Heart J 2009; 158(2):302-8.
Clavel MA, Webb JG, Pibarot P, Altwegg L, Dumont E, Thompson C, De Larochellière R, Doyle D, Masson JB, Bergeron S, Bertrand OF, Rodés-Cabau J. Comparison of the hemodynamic performance of percutaneous and surgical bioprostheses for the treatment of severe aortic stenosis.. J Am Coll Cardiol 2009; 53(20):1883-91.
Adda J, Stanova V, Zenses AS, Clavel MA, Barragan P, Penaranda G, Habib G, Pibarot P, Rieu R.. Discordand Grading of Aortic Stenosis Severity: New Insights from an In Vitro Study.. Struct Heart 2019; 3(5):415-422.
Després AA, Perrot N, Poulin A, Tastet L, Shen M, Bourgeois R, Trottier M, Tessier M, Guimont J, Nadeau M, Thériault S, Bossé Y. Witzum JL, Couture P, Mathieu P, Dweck M, Tsimikas S, Thanassoulis G, Pibarot P, Clavel MA, Arsenault BJ.. Lipoprotein(a), oxidized phospholipids and aortic valve microcalcification assessed by 18-NaF PET/CT.. CJC Open 2019; 1(3):131-140.
Hervault M, Clavel MA.. Sex-related differencies in calcific aortic stenosis: Pathophysiology, epidemiology, etiology, diagnosis, presentation and outcomes.. Struc Heart 2018; 2(2):102-113.
Clavel MA, Guzzetti E, Annabi MS, Salaun E, Ong G, Pibarot P.. Altmetric review articles normal-flow low-gradient severe aortic stenosis: Myth ot reality?. Struct Heart 2018; 2(3):180-187.
Sá MPBO, Cavalcanti LRP, Rayol SDC, Diniz RGS, Menezes AM, Clavel MA, Pibarot P, Lima RC.. Prosthesis-Patient Mismatch Negatively Affects Outcomes after Mitral Valve Replacement: Meta-Analysis of 10,239 Patients.. Braz J Cardiovasc Surg 2019; 34(2):203-212.
Tastet L, Pibarot P, Shen M, Clisson M, Côté N, Salaun E, Arsenault M, Bédard É, Capoulade R, Puri R, Poirier P, Clavel MA.. Oral Anticoagulation Therapy and Progression of Calcific Aortic Valve Stenosis.. J Am Coll Cardiol 2019; 73(14):1869-1871.
Annabi MS, Clavel MA, Pibarot P.. Dobutamine Stress Echocardiography in Low-Flow, Low-Gradient Aortic Stenosis: Flow Reserve Does Not Matter Anymore.. J Am Heart Assoc 2019; 8(6):e012212.
Oury C, Côté N, Clavel MA.. Biomarkers Associated with Aortic Stenosis and Structural Bioprosthesis Dysfunction.. Cardiol Clin 2020; 38(1):47-54.
Shen M, Tastet L, Capoulade R, Arsenault M, Bédard É, Clavel MA, Pibarot P.. Effect of Bicuspid Aortic Valve Phenotype on Progression of Aortic Stenosis.. Eur Heart J Cardiovasc Imaging 2020; 21(7):727-734.
Perrot N, Thériault S, Dina S, Chen HY, Boekholdt SM, Rigade S, Després MA, Poulin A, Capoulade R, Le Tourneau T, Messika-Zeitoun D, Trottier M, Tessier M, Guimond J, Nadeau M, Engert J, Khaw KT, Wareham NJ, Dweck MR, Mathieu P, Pibarot P, Schott JJ, Thanassoulis G, Clavel MA, Bossé Y, Arsenault BJ.. Variation in LPA and calcific aortic valve stenosis in patients undergoing cardiac surgery and familial risk of aortic valve microcalcification.. JAMA Cardiol 2019; 4(7):620-627.
Perrot N, Thériault S, Dina S, Chen HY, Boekholdt SM, Rigade S, Després MA, Poulin A, Capoulade R, Le Tourneau T, Messika-Zeitoun D, Trottier M, Tessier M, Guimond J, Nadeau M, Engert J, Khaw KT, Wareham NJ, Dweck MR, Mathieu P, Pibarot P, Schott JJ, Thanassoulis G, Clavel MA, Bossé Y, Arsenault BJ.. Variation in LPA and calcific aortic valve stenosis in patients undergoing cardiac surgery and familial risk of aortic valve microcalcification.. JAMA Cardiol 2019; 4(7):620-627.
Norris CM, Yip CYY, Nerenberg KA, Clavel MA, Pacheco C, Foulds HJA, Hardy M, Gonsalves CA, Jaffer S, Parry M, Colella TJF, Dhukai A, Grewal J, Price JAD, Levinsson ALE, Hart D, Harvey PJ, Van Spall HGC, Sarfi H, Sedlak TL, Ahmed SB, Baer C, Coutinho T, Edwards JD, Green CR, Kirkham AA, Srivaratharajah K, Dumanski S, Keeping-Burke L, Lappa N, Reid RD, Robert H, Smith G, Martin-Rhee M, Mulvagh SL.. State of the Science in Women's Cardiovascular Disease: A Canadian Perspective on the Influence of Sex and Gender.. J Am Heart Assoc 2020; 9(4):e015634.
Guzzetti E, Clavel MA, Pibarot P. Importance of Flow in Risk Stratification of Aortic Stenosis.. Can J Cardiol 2020; 36(1):27-29.
Côté N, Clavel MA.. Sex Differences in the Pathophysiology, Diagnosis, and Management of Aortic Stenosis.. Cardiol Clin 2020; 38(1):129-138.
Chen S, Redfors B, O'Neill BP, Clavel MA, Pibarot P, Elmariah S, Nazif T, Crowley A, Ben-Yehuda O, Finn MT, Alu MC, Vahl TP, Kodali S, Leon MB, Lindman BR. Low and elevated B-type natriuretic peptide levels are associated with increased mortality in patients with preserved ejection fraction undergoing transcatheter aortic valve replacement: an analysis of the PARTNER II trial and registry.. Eur Heart J 2020; 41(8):958-969.
Ternacle J, Krapf L, Mohty D, Magne J, Nguyen A, Galat A, Gallet R, Teiger E, Côté N, Clavel MA, Tournoux F, Pibarot P, Damy T.. Aortic Stenosis and Cardiac Amyloidosis: JACC Review Topic of the Week.. J Am Coll Cardiol 2019; 74(21):2638-2651.
Gazzola M, Khadangi F, Clisson M, Beaudoin J, Clavel MA, Bossé Y.. Shortening of airway smooth muscle is modulated by prolonging the time without simulated deep inspirations in ovine tracheal strips.. J Appl Physiol (1985) 2019; 127(6):1528-1538.
Pawade T, Sheth T, Guzzetti E, Dweck MR, Clavel MA.. Why and How to Measure Aortic Valve Calcification in Patients With Aortic Stenosis.. JACC Cardiovasc Imaging 2019; 12(9):1835-1848.
Tastet L, Kwiecinski J, Pibarot P, Capoulade R, Everett RJ, Newby DE, Shen M, Guzzetti E, Arsenault M, Bédard É, Larose E, Beaudoin J, Dweck M, Clavel MA. Sex-Related Differences in the Extent of Myocardial Fibrosis in Patients With Aortic Valve Stenosis.. JACC Cardiovasc Imaging 2020; 13(3):699-711.
Tastet L, Tribouilloy C, Maréchaux S, Vollema EM, Delgado V, Salaun E, Shen M, Capoulade R, Clavel MA, Arsenault M, Bédard É, Bernier M, Beaudoin J, Narula J, Lancellotti P, Bax JJ, Généreux P, Pibarot P.. Staging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis.. J Am Coll Cardiol 2019; 74(4):550-563.
Guzzetti E, Pibarot P, Clavel MA.. Normal-flow low-gradient severe aortic stenosis is a frequent and real entity.. Eur Heart J Cardiovasc Imaging 2019; 20(10):1102-1104.
Ternacle J, Côté N, Krapf L, Nguyen A, Clavel MA, Pibarot P.. Chronic Kidney Disease and the Pathophysiology of Valvular Heart Disease.. Can J Cardiol 2019; 35(9):1195-1207.
Pompeu M, Cavalcanti LRP, Escorel ACA, Perazzo AM, Simonato M, Clavel MA, Pibarot P, Lima RC.. Early Aortic Valve Replacement versus Watchful Waiting in Asymptomatic Severe Aortic Stenosis: A Study level Meta analysis.. Struct Heart 2019; 3(6):483-490.
Everett RJ, Treibel TA, Fukui M, Lee H, Rigolli M, Singh A, Bijsterveld P, Tastet L, Musa TA, Dobson L, Chin C, Captur G, Om SY, Wiesemann S, Ferreira VM, Piechnik SK, Schulz-Menger J, Schelbert EB, Clavel MA, Newby DE, Myerson SG, Pibarot P, Lee S, Cavalcante JL, Lee SP, McCann GP, Greenwood JP, Moon JC, Dweck MR1.. Extracellular Myocardial Volume in Patients With Aortic Stenosis.. J Am Coll Cardiol 2020; 75(3):304-316.
Thériault S, Dina C, Messika-Zitoun D, Le Scouarnec S, Capoulade R, Gaudreault N, Rigade S, Li Z, Simonet F, Lamontagne M, Clavel MA, Arsenault BJ, Boureau AS, Lecointe S, Baron E, Bonnaud S, Karakachoff M, Charpentier E, Fellah I, Roussel JC, Verhoye JP, Baufreton C, Probst V, Roussel R, the D.E.S.I.R. Study Group, Redon R, Dagenais F, Pibarot P, Mathieu P, Le Tourneau T, Bossé Y, Schott JJ.. Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis. Circ Genom Precis Med 2019; 12(10):e002617.
de Oliveira Sá MPB, Cavalcanti LRP, Perazzo ÁM, Gomes RAF, Clavel MA, Pibarot P, Biondi-Zoccai G, Zhigalov K, Weymann A, Ruhparwar A, Lima RC.. Calcific Aortic Valve Stenosis and Atherosclerotic Calcification.. Curr Atheroscler Rep 2020; 22(2):2.
Clavel MA, Pibarot P.. A Decade of Revolutions in Calcific Aortic Stenosis.. Cardiol Clin 2020; 38(1):xiii-xiv.
Gazzola M, Khadangi F, Clisson M, Beaudoin J, Clavel MA, Bossé Y.. Airway smooth muscle adapting in dynamic conditions is refractory to the bronchodilator effect of a deep inspiration.. Am J Physiol Lung Cell Mol Physiol 2020; 318(2):L452-L458.
Marsit O, Clavel MA, Côté-Laroche C, Hadjadj S, Bouchard MA, Handschumacher MD, Clisson M, Drolet MC, Boulanger MC, Kim DH, Guerrero JL, Bartko PE, Couet J, Arsenault M, Mathieu P, Pibarot P, Aïkawa E, Bischoff J, Levine RA, Beaudoin J. Attenuated Mitral Leaflet Enlargement Contributes to Functional Mitral Regurgitation After Myocardial Infarction.. J Am Coll Cardiol 2020; 75(4):395-405.
Freitas-Ferraz AB, Lerakis S, Barbosa Ribeiro H, Gilard M, Cavalcante JL, Makkar R, Herrmann HC, Windecker S, Enriquez-Sarano M, Cheema AN, Nombela-Franco L, Amat-Santos I1, Muñoz-García AJ, Garcia Del Blanco B, Zajarias A, Lisko JC, Hayek S, Babaliaros V, Le Ven F, Gleason TG, Chakravarty T, Szeto WY, Clavel MA, de Agustin A, Serra V, Schindler JT, Dahou A, Annabi MS, Pelletier-Beaumont E, Pibarot P, Rodés-Cabau J. Mitral Regurgitation in Low-Flow, Low-Gradient Aortic Stenosis Patients Undergoing TAVR: Insights From the TOPAS-TAVI Registry.. JACC Cardiovasc Interv 2020; 13(5):567-579.
Ternacle J, Clavel MA.. Assessment of Aortic Stenosis Severity: A Multimodality Approach.. Cardiol Clin 2020; 38(1):13-22.
Guzzetti E, Poulin A, Annabi MA, Zhang B, Kalavrouziotis D, Couture C, Dagenais F, Pibarot P, Clavel MA.. Transvalvular Flow, Sex, and Survival After Valve Replacement Surgery in Patients With Severe Aortic Stenosis.. J Am Coll Cardiol 2020; 75(16):1897-1909.
Pibarot P, Lauck S, Morris T, Ross E, Harding E, Wijeysundera HC, Clavel MA, Bewick D, Oh P, Bédard S, Socransky B, Afilalo J, Rhéaume C, Asgar A, Budig K, Ruel M, Peniston C.. Patient Care Journey for Patients with Heart Valve Disease.. Can J Cardiol 2022; 38(8):1296-1299.
Tastet L, Shen M, Capoulade R, Arsenault M, Bédard É, Côté N, Clavel MA, Pibarot P.. Bone Mineral Density and Progression Rate of Calcific Aortic Valve Stenosis.. J Am Coll Cardiol 2020; 75(14):1725-1726.
Benfari G, Mantovani F, Romero-Brufau S, Setti M, Rossi A, Ribichini FL, Nistri S, Clavel MA.. The Right Parasternal Window: When Doppler-beam Alignment May Be Life-Saving in Patients With Aortic Valve Stenosis.. J Cardiovasc Med (Hagerstown) 2020; 21(10):831-834.
Voisine M, Hervault M, Shen M, Boilard AJ, Filion B, Rosa M, Bossé Y, Mathieu P, Côté N, Clavel MA.. Age, Sex, and Valve Phenotype Differences in Fibro-Calcific Remodeling of Calcified Aortic Valve.. J Am Heart Assoc 2020; 9(10):e015610.
Gonzales H, Douglas PS, Pibarot P, Hahn RT, Khalique OK, Jaber WA, Cremer P, Weissman NJ, Asch FM, Zhang Y, Gertz ZM, Elmariah S, Clavel MA, Thourani VH, Daubert M, Alu MC, Leon B, Lindman BR.. Left Ventricular Hypertrophy and Clinical Outcomes Over 5 Years After TAVR: An analysis of the PARTNER Trials and Registries.. JACC Cardiovasc Interv 2020; 13(11):1329-1339.
Barbieri A, Antonini-Canterin F, Pepi M, Monte IP, Trocino G, Barchitta A, Ciampi Q, Cresti A, Miceli S, Petrella L, Benedetto F, Zito C, Benfari G, Bursi F, Malagoli A, Bartolacelli Y, Mantovani F, Clavel MA. Discordant Echocardiographic Grading in Low Gradient Aortic Stenosis (DEGAS Study) From the Italian Society of Echocardiography and Cardiovascular Imaging Research Network: Rationale and Study Design.. J Cardiovasc Echogr 2020; 30(2):52-61.
Guzzetti E, Capoulade R, Tastet L, Garcia J, Le Ven F, Arsenault M, Bédard É, Larose E, Clavel MA, Pibarot P.. Estimation of Stroke Volume and Aortic Valve Area in Patients With Aortic Stenosis: A Comparison of Echocardiography Versus Cardiovascular Magnetic Resonance.. J Am Soc Echocardiogr 2020; 33(8):953-963.e5.
Salaun E, Clavel MA, Hahn RT, Jaber WA, Asch FM, Rodriguez L, Weissman NL, Gertz ZM, Herrmann HC, Dahou A, Annabi MS, Toubal O, Bernier M, Beaudoin J, Leipsic J, Blanke P, Ridard C, Ong G, Rodés-Cabau J, Webb JG, Zhang Y, Alu MC, Douglas PS, Makkar R, Miller DC, Lindman BR, Thourani VH, Leon MB, Pibarot P. Outcome of Flow-Gradient Patterns of Aortic Stenosis After Aortic Valve Replacement: An Analysis of the PARTNER 2 Trial and Registry.. Circ Cardiovasc Interv 2020; 13(7):e008792.
O'Leary JM, Clavel MA, Chen S, Goel K, O'Neill B, Elmariah S, Crowley A, Alu MC, Thourani VH, Leon MB, Pibarot P, Lindman BR.. Association of Natriuretic Peptide Levels After Transcatheter Aortic Valve Replacement With Subsequent Clinical Outcomes.. JAMA Cardiol 2020; 5(10):1113-1123.
Guzzetti E, Simard L, Clisson M, Clavel MA.. Multiplanar "En Face" Reconstruction of the Aortic Valve: Impact on Aortic Valve Calcium Scoring.. JACC Cardiovasc Imaging 2020; 13(12):2678-2680.
Annabi MS, Côté N, Dahou A, Bartko PE, Bergler-Klein J, Burwash IG, Orwat S, Baumgartner H, Mascherbauer J, Mundigler G, Fukui M, Cavalcante J, Ribeiro HB, Rodès-Cabau J, Clavel MA, Pibarot P. Comparison of Early Surgical or Transcatheter Aortic Valve Replacement Versus Conservative Management in Low-Flow, Low-Gradient Aortic Stenosis Using Inverse Probability of Treatment Weighting: Results From the TOPAS Prospective Observational Cohort Study.. J Am Heart Assoc 2020; 0(0):e017870.
Mantovani F, Clavel MA, Potenza A, Leuzzi C, Grimaldi T, Vignali L, Navazio A, Guiducci V.. Balloon aortic valvuloplasty as a palliative treatment in patients with severe aortic stenosis and limited life expectancy: a single center experience.. Aging (Albany NY) 2020; 12(16):16597-16608.
Perrot N, Valerio V, Moschetta D, Boekholdt SM, Dina C, Chen HY, Abner E, Martinsson A, Manikpurage HD, Rigade S, Capoulade R, Mass E, Clavel MA, Le Tourneau T, Messika-Zitoun D, Wareham NJ, Engert JC, Polvani G, Pibarot P, Esko T, Smith JG, Mathieu P, Thanassoulis G, Schott JJ, Bossé Y, Camera M, Thériault S, Poggio P, Arsenault BJ. Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis.. JACC Basic Transl Sci 2020; 5(7):649-661.
Ternacle J, Faroux L, Alperi A, Muntané-Carol G, Delarochellière R, Paradis JM, Kalavrouziotis D, Mohammadi S, Dumont E, Beaudoin J, Bernier M, Côté N, Côté M, Vincent F, Clavel MA, Rodés-Cabau J, Pibarot P. Impact of Left Ventricular Dysfunction in Patients with High and Low Gradient Severe Aortic Stenosis Following Transcatheter Aortic Valve Replacement.. Can J Cardiol 2021; 37(7):1103-1111.
Pibarot P, Ternacle J, Jaber WA, Salaun E, Dahou A, Asch FM, Weissman NJ, Rodriguez L, Xu K, Annabi MS, Guzzetti E, Beaudoin J, Bernier M, Leipsic J, Blanke P, Clavel MA, Rogers E, Alu MC, Douglas PS, Makkar R, Miller DC, Kapadia SR, Mack MJ, Webb JG, Kodali SK, Smith CR, Herrmann HC, Thourani VH, Leon MB, Hahn RT; PARTNER 2 Investigators.. Structural Deterioration of Transcatheter Versus Surgical Aortic Valve Bioprostheses in the PARTNER-2 Trial.. J Am Coll Cardiol 2020; 76(16):1830-1843.
Zhang B, Salaun E, Côté N, Wu Y, Mahjoub H, Mathieu P, Dahou A, Zenses AS, Clisson M, Pibarot P, Clavel MA.. Association of Bioprosthetic Aortic Valve Leaflet Calcification on Hemodynamic and Clinical Outcomes.. J Am Coll Cardiol 2020; 76(15):1737-1748.
Guzzetti E, Clavel MA.. Measuring progression of aortic stenosis: computed tomography versus echocardiography.. Heart 2020; 106(24):1873-1875.
Guzzetti E, Tastet L, Annabi MS, Capoulade R, Shen M, Bernard J, García J, Le Ven F, Arsenault M, Bédard É, Larose E, Clavel MA, Pibarot P.. Effect of Regional Upper Septal Hypertrophy on Echocardiographic Assessment of Left Ventricular Mass and Remodeling in Aortic Stenosis.. J Am Soc Echocardiogr 2021; 34(1):62-71.
Guzzetti E, Poulin A, Annabi MS, Kalavrouziotis D, Dagenais F, Pibarot P, Clavel MA.. Pre- and Post-Operative Stroke Volume Impact After Surgical Aortic Valve Replacement for Severe Aortic Stenosis.. J Am Coll Cardiol 2020; 76(17):2036-2038.
Unger P, Clavel MA.. Mixed Aortic Valve Disease: A Diagnostic Challenge, a Prognostic Threat.. J Struct Heart Dis 2020; 0(0):Epub.
Ternacle J, Guimaraes L, Vincent F, Côté N, Côté M, Lachance D, Clavel MA, Abbas AE, Pibarot O, Rodés-Cabau J.. Reclassification of prosthesis-patient mismatch after transcatheter aortic valve replacement using predicted vs. measured indexed effective orifice area.. Eur Heart J Cardiovasc Imaging 2021; 22(1):11-20.
Perrot N, Thériault S, Rigade S, Chen HY, Dina C, Martinsson A, Boekholdt M, Capoulade R, Le Tourneau T, Messika-Zeitoun D, Engert JC, Wareham NJ, Clavel MA, Pibarot P, Smith G, Schott JJ, Mathieu P, Bossé Y, Thanassoulis G, Arsenault BJ. Lipoprotein-associated phospholipase A2 activity, genetics and calcific aortic valve stenosis in humans.. Heart 2020; 106(18):1407-1412.
Jenkins WS, Simard L, Clavel MA, Foley TA, Araoz PA, Miller JD, Thaden J, Messika-Zeitoun D, Enriquez-Sarano M. Pathophysiology of Aortic Valve Calcification and Stenosis: Novel Insights From Reconstructed Multiplanar Computed Tomography.. JACC Cardiovasc Imaging 2020; 13(10):2255-2258.
Annabi MS, Clisson M, Fleury MA, Voisine M, Hervault M, Shen M, Boilard AJ, Marette A, Ong G, Côté N, Clavel MA. Sex-differences in echocardiographic assessment of aortic valve in young adult LDLr^-/-/ApoB^100/100/IGF-II^+/- mice.. Exp Gerontol 2020; 140(0):111075.
Sa MPBO, Van den Eynde J, Simonato M, Cavalcanti LRP, Doulamis IP, Weixler V, Kampaktsis PN, Gallo M, Laforgia PL, Zhigalov K, Ruhparwar A, Weymann A, Pibarot P, Clavel MA. Valve-in-Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement: An Updated Meta-Analysis.. JACC Cardiovasc Interv 2021; 14(2):211-220.
Porterie J, Salaun E, Ternacle J, Clavel MA, Dagenais F. Stress exercise haemodynamic performance and opening reserve of a stented bovine pericardial aortic valve bioprosthesis.. J Card Surg 2022; 37(3):618-627.
Vamvakidou A, Annabi MS, Pibarot P, Plonska-Gosciniak E, Almeida AG, Guzzetti E, Dahou A, Burwash IG, Koschutnik M, Bartko PE, Bergler-Klein J, Mascherbauer J, Orwat S, Baumgartner H, Cavalcante J, Pinto F, Kukulski T, Kasprzak JD, Clavel MA, Flachskampf FA, Senior R.. Clinical Value of Stress Transaortic Flow Rate During Dobutamine Echocardiography in Reduced Left Ventricular Ejection Fraction, Low-Gradient Aortic Stenosis: A Multicenter Study.. Circ Cardiovasc Imaging 2021; 14(11):e012809.
Guzzetti E, Annabi MS, Pibarot P, Clavel MA. Multimodality Imaging for Discordant Low-Gradient Aortic Stenosis: Assessing the Valve and the Myocardium.. Front Cardiovasc Med 2020; 7(0):570689.
Pompeu M, Chernov I, Marchenko A, Chagyan V, Komarov R, Askadinov M, Enginoev S, Kadyralilev B, Ismailbaev A, Tcheglov M, Clavel MA, Pibarot P, Ruhparwar A, Weymann A, Zhigalov K.. Aortic valve neocuspidization (Ozaki procedure) in patients with small aortic annulus (≤21mm): a multicenter study.. Struct Heart 2020; 4(5):413-419.
Clavel MA, Annabi MS. Low-Flow Aortic Stenosis: Flow Rate Does Not Replace But Could Refine Stroke Volume Index.. JACC Cardiovasc Imaging 2021; 14(5):928-930.
Bernard J, Tastet L, Capoulade R, Shen M, Clisson M, Guzzetti E, Larose E, Arsenault M, Bédard É, Côté N, Clavel MA, Pibarot P. Left ventricular asymmetric remodeling and subclinical left ventricular dysfunction in patients with calcific aortic valve stenosis - Results from a subanalysis of the PROGRESSA study.. Int J Cardiol 2021; 332(0):148-156.
Ternacle J, Pibarot P, Clavel MA.. Aortic Stenosis and Cardiac Amyloidosis: Watch Out for Traps!. JACC Case Rep 2020; 2(14):2210-2212.
Sengupta PP, Shrestha S, Kagiyama N, Hamirani Y, Kulkarni H, Yanamala N, Bing R, Chin CWL, Pawade TAm Messika-Zeitoun D, Tastet L, Shen M, Newby DE, Clavel MA, Pibarot P, Dweck MR; Artificial Intelligence for Aortic Stenosis at Risk International Consortium (Larose E, Bernier M, Beaudoin J, Arsenault M parmis les collaborateurs). A Machine-Learning Framework to Identify Distinct Phenotypes of Aortic Stenosis Severity. JACC Cardiovasc Imaging 2021; 14(9):1707-1720.
Bienjonetti-Boudreau D, Fleury MA, Voisine M, Paquin A, Chouinard I, Tailleur M, Duval R, Magnan PO, Beaudoin J, Salaun E, Clavel MA.. Impact of sex on the management and outcome of aortic stenosis patients.. Eur Heart J 2021; 42(27):2683-2691.
Dufour-Mailhot A, Boucher M, Henry C, Khadangi F, Tremblay-Pitre S, Clisson M, Beaudoin J, Clavel MA, Bossé Y. Flexibility of microstructural adaptations in airway smooth muscle.. J Appl Physiol (1985) 2021; 130(5):1555-1561.
Jaffer S, Foulds HJA, Parry M, Gonsalves CA, Pacheco C, Clavel MA, Mullen KA, Yip CYY, Mulvagh SL, Norris CM. The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women-Chapter 2: Scope of the Problem.. CJC Open 2021; 3(1):1-11.
Drouin-Chartier JP, Tremblay AJ, Godbout D, Gagnon A, Clavel MA, Clisson M, Arsenault BJ, Pibarot P, Larose E, Couture P. Correlates of Coronary Artery Calcification Prevalence and Severity in Patients With Heterozygous Familial Hypercholesterolemia.. CJC Open 2021; 3(1):62-70.
Guertin J, Kaiser Y, Manikpurage H, Perrot N, Bourgeois R, Couture C, Wareham NJ, Bossé Y, Pibarot P, Stroes ESG, Mathieu P, Clavel MA, Thériault S, Boekholdt SM, Arsenault BJ. Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes: Mendelian Randomization and Observational Analyses.. Circ Genom Precis Med 2021; 14(4):e003271.
Fadel BM, Alassas K, Clavel MA, Fekredeen Ayas M, Kazzi BE, Pibarot P, Mohty D.. Multiparametric Approach for the Assessment of Mechanical Prosthetic Tricuspid Leaflet Function.. J Am Soc Echocardiogr 2022; 35(2):206-216.
Guzzetti E, Racine HP, Tastet L, Shen M, Larose E, Clavel MA, Pibarot P, Beaudoin J. Accuracy of stroke volume measurement with phase-contrast cardiovascular magnetic resonance in patients with aortic stenosis.. J Cardiovasc Magn Reson 2021; 23(1):124.
Ternacle J, Pibarot P, Herrmann HC, Kodali S, Leipsic J, Blanke P, Jaber W, Mack MJ, Clavel MA, Salaun E, Guzzetti E, Annabi MS, Bernier M, Beaudoin J, Khalique OK, Weissman NJ, Douglas P, Bax J, Dahou A, Xu K, Alu M, Rogers E, Leon M, Thourani VH, Abbas AE, Hahn RT. Prosthesis-Patient Mismatch After Aortic Valve Replacement in the PARTNER 2 Trial and Registry.. JACC Cardiovasc Interv 2021; 14(13):1466-1477.
Châteauneuf G, De Larochellière H, Clavel MA, Kalavrouziotis D, Charbonneau E, Dagenais F, Morin F, Silva I, Turgeon PY, Paradis JM, Bernier M, Beaudoin J, Bergeron S, Rodés-Cabau J, Mohammadi S, Pibarot P, O'Connor K, Salaun E. Bioprosthetic Mitral Valve Thrombosis: A Multifaceted and Challenging Clinical and Imaging Spectrum.. JACC Cardiovasc Imaging 2022; 15(7):1339-1346.
Jean G, Pibarot P, Clavel MA. Reply: Calcium Score to Specify Assessment of Low-Flow Aortic Stenosis Severity.. J Am Coll Cardiol 2021; 78(11):e73.
Kwak S, Everett RJ, Treibel TA, Yang S, Hwang D, Ko T, Williams MC, Bing R, Singh T, Joshi S, Lee H, Lee W, Kim YJ, Chin CWL, Fukui M, Al Musa T, Rigolli M, Singh A, Tastet L, Dobson LE, Wiesemann S, Ferreira VM, Captur G, Lee S, Schulz-Menger J, Schelbert EB, Clavel MA, Park SJ, Rheude T, Hadamitzky M, Gerber BL, Newby DE, Myerson SG, Pibarot P, Cavalcante JL, McCann GP, Greenwood JP, Moon JC, Dweck MR, Lee SP. Markers of Myocardial Damage Predict Mortality in Patients With Aortic Stenosis.. J Am Coll Cardiol 2021; 78(6):545-558.
Hahn RT, Douglas PS, Jaber WA, Leipsic J, Kapadia S, Thourani VH, Makkar R, Kodali S, Clavel MA, Khalique OK, Weissman NJ, Blanke P, Chen Y, Smith CR, Mack MJ, Leon MB, Pibarot P. Doppler Velocity Index Outcomes Following Surgical or Transcatheter Aortic Valve Replacement in the PARTNER Trials.. JACC Cardiovasc Interv 2021; 14(14):1594-1606.
Guzzetti E, Oh JK, Shen M, Dweck MR, Poh KK, Abbas AE, Mando R, Pressman GS, Brito D, Tastet L, Pawade T, Falconi ML, de Arenaza DP, Kong W, Tay E, Pibarot P, Song JK, Clavel MA. Validation of aortic valve calcium quantification thresholds measured by computed tomography in Asian patients with calcific aortic stenosis.. Eur Heart J Cardiovasc Imaging 2022; 23(5):717-726.
Poirier P, Bastien M, Auclair A, Nadreau É, Clavel MA, Pibarot P, Bagur R, Forman DE, Rodès-Cabau J. The Physiological Burden of the 6-Minute Walk Test Compared With Cardiopulmonary Exercise Stress Test in Patients With Severe Aortic Atenosis.. CJC Open 2021; 3(6):769-777.
Jean G, Van Mieghem NM, Gegenava T, van Gils L, Bernard J, Geleijnse ML, Vollema EM, El Azzouzi I, Spitzer E, Delgado V, Bax JJ, Pibarot P, Clavel MA. Moderate Aortic Stenosis in Patients With Heart Failure and Reduced Ejection Fraction.. J Am Coll Cardiol 2021; 77(22):2796-2803.
Sá MPBO, Van den Eynde J, Simonato M, Pibarot P, Clavel MA. Reply: Meta-Analysis: Valve-in-Valve TAVR Versus Redo SAVR.. JACC Cardiovasc Interv 2021; 14(10):1157-1158.
Sá MPBO, Van den Eynde J, Simonato M, Pibarot P, Clavel MA. Reply: Valve-in-Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement.. JACC Cardiovasc Interv 2021; 14(8):927-928.
Piché ME, Clavel MA, Auclair A, Rodríguez-Flores M, O'Connor K, Garceau P, Rakowski H, Poirier P. Early benefits of bariatric surgery on subclinical cardiac function: Contribution of visceral fat mobilization.. Metabolism 2021; 119(0):154773.
Fleury MA, Clavel MA. Sex and Race Differences in the Pathophysiology, Diagnosis, Treatment, and Outcomes of Valvular Heart Diseases.. Can J Cardiol 2021; 37(7):980-991.
Cartlidge TR, Bing R, Kwiecinski J, Guzzetti E, Pawade TA, Doris MK, Adamson PD, Massera D, Lembo M, Peeters FECM, Couture C, Berman DS, Dey D, Slomka P, Pibarot P, Newby DE, Clavel MA, Dweck MR. Contrast-enhanced computed tomography assessment of aortic stenosis.. Heart 2021; 107(23):1905-1911.
Annabi MS, Zhang B, Bergler-Klein J, Dahou A, Burwash IG, Guzzetti E, Ong G, Tastet L, Orwat S, Baumgartner H, Bartko EP, Koschtnik M, Mascherbauer J, Mundigler G, Cavalcante J, Ribeiro HB, Rodés-Cabau J, Pibarot P, Clavel MA.. Usefulness of the B-Type Natriuretic Peptides in Low Ejection Fraction, Low-Flow, Low-Gradient Aortic Stenosis Results from the TOPAS Multicenter Prospective Cohort Study.. Struct Heart 2021; 5(3):319-327.
Khelifi N, Blais C, Jean S, Hamel D, Clavel MA, Pibarot P, Mac-Way F.. Temporal trends of aortic stenosis and comorbid chronic kidney disease in the province of Quebec, Canada.. Open Heart 2022; 9(1):e001923.
Fukui M, Annabi MS, Rosa VEE, Ribeiro HB, Stanberry LI, Clavel MA, Rodés-Cabau J, Tarasoutchi F, Schelbert EB, Bergler-Klein J, Bartko PE, Dona C, Mascherbauer J, Dahou A, Rochitte CE, Pibarot P, Cavalcante JL.. Comprehensive myocardial characterization using cardiac magnetic resonance associates with outcomes in low gradient severe aortic stenosis.. Eur Heart J Cardiovasc Imaging 2022; 24(1):46-58.
Parry M, Van Spall HGC, Mullen KA, Mulvagh SL, Pacheco C, Colella TJF, Clavel MA, Jaffer S, Foulds HJA, Grewal J, Hardy M, Price JAD, Levinsson ALE, Gonsalves CA, Norris CM.. The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 6: Sex- and Gender-Specific Diagnosis and Treatment.. CJC Open 2022; 4(7):589-608.
Hadjadj S, Freitas-Ferraz AB, Paquin A, Rouleau Z, Simard S, Bernier M, O'Connor K, Salaun E, Pibarot P, Clavel MA, Rodés-Cabau J, Paradis JM, Beaudoin J. Echocardiographic Variables Associated with Transvalvular Gradient After a Transcatheter Edge-To-Edge Mitral Valve Repair.. J Am Soc Echocardiogr 2022; 35(1):86-95.
Pacheco C, Mullen KA, Coutinho T, Jaffer S, Parry M, Van Spall HGC, Clavel MA, Edwards JD, Sedlak T, Norris CM, Dhukai A, Grewal J, Mulvagh SL. The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 5: Sex- and Gender-Unique Manifestations of Cardiovascular Disease.. CJC Open 2022; 4(3):243-262.
Frieden P, Blais C, Hamel D, Gamache P, Pibarot P, Clavel MA. Evolution of the burden of aortic stenosis by sex in the province of Quebec between 2006 and 2018.. Heart 2022; 108(20):1644-1650.
Krasniqi L, Schødt Riber LP, Nissen H, Terkelsen CJ, Andersen NH, Freeman P, Povlsen JA, Gerke O, Clavel MA, Jordi Dahl.. Impact of mandatory preoperative dental screening on post-procedural risk of infective endocarditis in patients undergoing transcatheter aortic valve implantation: a nationwide retrospective observational study.. Lancet Reg Health Eur 2023; 36(0):100789.
Paquin A, Marsit O, Deschênes V, Rouabhia D, Hadjadj S, Clisson M, Robitaille C, Aikawa E, Levine RA, Pibarot P, Clavel MA, Beaudoin J.. Progression of aortic stenosis after an acute myocardial infarction.. Open Heart 2022; 9(1):e002046.
Sa MP, Van den Eynde J, Jacquemyn X, Tasoudis P, Erten O, McDonald C, Weymann A, Ruhparwar A, Clavel MA, Pibarot P, Calhoon J, Ramlawi B.. Long-Term Outcomes of Ross Procedure versus Mechanical Aortic Valve Replacement: Meta-Analysis of Reconstructed Time-To-Event Data.. Trends Cardiovasc Med 2022; 0(0):Epub.
Altes A, Bernard J, Dumortier H, Dupuis M, Toubal O, Mahjoub H, Tartar J, Côté N, Clavel MA, O'Connor K, Bernier M, Beaudoin J, Vincentilli A, Pibarot P, Maréchaux S.. Significance of Left Ventricular Ejection Time in Primary Mitral Regurgitation.. Am J Cardiol 2022; 178(0):97-105.
Tastet L, Shen M, Capoulade R, Arsenault M, Bédard É, Ternacle J, Salaun E, Côté N, Pibarot P, Clavel MA.. Sex Differences in the Progression of Aortic Valve Calcification and Clinical Outcomes: The PROGRESSA Study.. JACC Cardiovasc Imaging 2022; 15(7):1349-1351.
Mantovani F, Benfari G, Barbieri A, Manca F, Guiducci V, Navazio A, Clavel MA.. Case Report: Posterior Thoracic Window in the Presence of Pleural Effusion in Critical Care Medicine: One More Chance to Image the Aortic Valve.. Front Cardiovasc Med 2022; 9(0):907168.
Carter-Storch R, Hansen SM, Dahl JS, Enevold K, Mogensen NSC, Berg H, Clavel MA, Møller JE.. Hemodynamic changes during aortic valve surgery among patients with aortic stenosis.. Scand Cardiovasc J 2022; 56(1):276-284.
Ye Z, Enriquez-Sarano M, Medina-Inojosa JR, Scott CG, Malouf J, Jaffe A, Clavel MA, Michelena HI.. Incremental Prognostic Value of Semiautomated Left Ventricular Strain to BNP in Asymptomatic Aortic Stenosis.. JACC Cardiovasc Imaging 2022; 15(5):947-950.
Hahn RT, Clavel MA, Mascherbauer J, Mick SL, Asgar AW, Douglas PS.. Sex-Related Factors in Valvular Heart Disease: JACC Focus Seminar 5/7.. J Am Coll Cardiol 2022; 79(15):1506-1518.
Marsit O, Clavel MA, Paquin A, Deschênes V, Hadjadj S, Sénéchal-Dumais I, Couet J, Arsenault M, Handschumacher MD, Levine RA, Aikawa E, Pibarot P, Beaudoin J. Effects of Cyproheptadine on Mitral Valve Remodeling and Regurgitation After Myocardial Infarction.. J Am Coll Cardiol 2022; 80(5):500-510.
Cahill TJ, Pibarot P, Yu X, Babaliaros V, Blanke P, Clavel MA, Douglas PS, Khalique OK, Leipsic J, Makkar R, Alu MC, Kodali S, Mack MJ, Leon MB, Hahn RT. Impact of Right Ventricle-Pulmonary Artery Coupling on Clinical Outcomes in the PARTNER 3 Trial.. JACC Cardiovasc Interv 2022; 15(18):1823-1833.
Pibarot P, Clavel MA. Live longer and better without aortic valve stenosis.. Lancet Healthy Longev 2022; 3(9):e573-e574.
Fleury MA, Annabi MS, Voisine M, Hervault M, Boilard AJ, Shen M, Marette A, Côté N, Clavel MA. Impact of sex and sex hormones on pathophysiology and progression of aortic stenosis in a murine model.. Physiol Rep 2022; 10(16):e15433.
Kolte D, Bhardwaj B, Lu M, Alu MC, Passeri JJ, Inglessis I, Vlahakes GJ, Garcia S, Cohen DJ, Lindman BR, Kodali S, Thourani VH, Daubert MA, Douglas PS, Jaber W, Pibarot P, Clavel MA, Palacios IF, Leon MB, Smith CR, Mack MJ, Elmariah S. Association Between Early Left Ventricular Ejection Fraction Improvement After Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes.. JAMA Cardiol 2022; 7(9):934-944.
Sá MP, Jacquemyn X, Van den Eynde J, Serna‐Gallegos D, Chu D, Clavel MA, Pibarot P, Sultan I.. Midterm Survival of Low-Risk Patients Treated With Transcatheter Versus Surgical Aortic Valve Replacement: Meta-Analysis of Reconstructed Time-to-Event Data.. J Am Heart Assoc 2023; 12(21):e030012.
Adda J, Stanova V, Zenses AS, Clavel MA, Barragan P, Penaranda G, Habib G, Pibarot P, Rieu R.. Discordant Grading of Aortic Stenosis Severity: New Insights from an In Vitro Study.. Struct Heart 2019; 3(5):415-422.
Borg Mogensen NS, Ali M, Carter-Storch R, Annabi MS, Grenier-Delaney J, Eifer Møller J, Altern Øvrehus K, Pellikka PA, Pibarot P, Clavel MA, Sanchez Dahl J.. Dobutamine Stress Echocardiography in Low-Gradient Aortic Stenosis.. medRxiv 2023; 0(0):Epub.
Powers A, Lavoie N, Le Nezet E, Clavel MA.. Unique Aspects of Women's Valvular Heart Diseases: Impact for Diagnosis and Treatment.. CJC Open 2023; 0(0):Epub.
Shen M, Oh JK, Guzzetti E, Singh GK, Pawade T, Tastet L, Clavel MA, Delgado V, Bax JJ, Dweck MR, Abbas AE, Mando R, Falconi ML, Peres de Arenaza D, Poh KK, Kong W, Tay E, Pressman G, Brito D, Song JK, Pibarot P.. Computed Tomography Aortic Valve Calcium Scoring in Patients With Bicuspid Aortic Valve Stenosis.. Struct Heart 2022; 6(1):100027.
Hecht S, Zenses AS, Bernard Jm Tastet L, Côté N, de Freitas Campos Guimaraes L, Paradis JM, Beaudoin J, O'Connor K, Bernier M, Dumont É, Kalavrouziotis D, De Larochellière R, Mohammadi S, Clavel MA, Rodés-Cabau J, Salaun E, Pibarot P.. Hemodynamic and Clinical Outcomes in Redo-Surgical Aortic Valve Replacement vs. Transcatheter Valve-in-Valve.. Struct Heart 2022; 6(6):100106.
Deslandes M, Paquin A, Guzzetti E, Beaudoin J, Barriault A, Salaun E, Clavel MA. Sex-specific correlates of valvular and arterial calcification burden in patients with moderate aortic stenosis.. Open Heart 2022; 9(2):e002139.
Bernard J, Altes A, Dupuis M, Toubal O, Mahjoub H, Tastet L, Côté N, Clavel MA, Dumortier H, Tartar J, O'Connor K, Bernier B, Beaudoin J, Maréchaux S, Pibarot P.. Cardiac Damage Staging Classification in Asymptomatic Moderate or Severe Primary Mitral Regurgitation.. Struct Heart 2022; 6(1):100004.
Altes A, Bernard J, Dumortier H, Dupuis M, Toubal O, Mahjoub H, Tartar J, Côté N, Clavel MA, OConnor K, Bernier M, Vincentelli A, Pibarot P, Maréchaux S.. Clinical significance of myocardial contraction fraction in significant primary mitral regurgitation.. Arch Cardiovasc Dis 2023; 116(3):151-158.
Pompeu M, Jacquemyn X, Van den Eynde J, Tasoudis P, Erten O, Sicouri S, Macedo FY, Pasala T, Kaple R, Weymann A, Ruhparwar A, Clavel MA, Pibarot P, Ramlawi B.. Impact of Paravalvular Leak on Outcomes After Transcatheter Aortic Valve Implantation: Meta-Analysis of Kaplan-Meier-derived Individual Patient Data.. Struct Heart 2022; 0(0):100118.
Girard A, Gaillard E, Puri R, Capoulade R, Chan KL, Paulin A, Manikpurage HD, Dumesnil J, Tam JW, Teo KK, Couture C, Wareham NJ, Clavel MA, Stroes ESG, Mathieu P, Thériault S, Tsimikas S, Pibarot P, Boekholdt SM, Arsenault BJ.. Impact of C-reactive protein levels on lipoprotein(a)-associated aortic stenosis incidence and progression.. Eur Heart J Open 2023; 3(2):oead032.
Dehghani P, Singh J, Singer Z, Booker J, Lavoie AJ, Zimmerman RH, Shavadia JS, Webb JG, Clavel MA, Pibarot P.. Catheter-Induced Postextrasystolic Potentiation in the Assessment of Severity of Low-Gradient Aortic Valve Stenosis. Circ Cardiovasc Interv 2023; 16(5):e012892.
Sá MP, Van den Eynde J, Jacquemyn X, Erten O, Rodriguez R, Goldman S, Coady PM, Gnall E, Gray WA, Jarrett H, Abramson SV, Clavel MA, Pibarot P, Ramlawi B.. Computed tomography-derived membranous septum length as predictor of conduction abnormalities and permanent pacemaker implantation after TAVI: A meta-analysis of observational studies.. Catheter Cardiovasc Interv 2023; 101(7):1203-1213.
Ludwig S, Schofer N, Abdel-Wahab M, Urena M, Jean G, Renker M, Hamm CW, Thiele H, Iung B, Ooms JF, Wiessman M, Mogensen NSB, Longère B, Perrin N, Ben Ali W, Coisne A, Dhal JS, Van Mieghem NM, Kornowski R, Kim WK, Clavel MA.. Transcatheter Aortic Valve Replacement in Patients With Reduced Ejection Fraction and Nonsevere Aortic Stenosis.. Circ Cardiovasc Interv 2023; 16(5):e012768.
Oh JK, Shen M, Guzzetti E, Tastet L, Loganath K, Botezatu S, Lee SA, Lee S, Kim DH, Song JM, Kang DH, Dweck MR, Pibarot P, Clavel MA, Song JK.. Effect of race on pressure recovery adjustment for prevention of aortic stenosis grading discordance.. Heart 2023; 109(20):1550-1557.
Silva I, Turgeon PY, Paradis JM, Beaudoin J, O'Connor K, Ternacle J, Alperi A, Panagides V, Mesnier J, Gravel C, Clavel MA, Dagenais F, Dumont E, Mohammadi S, Pibarot P, Bernier M, Rodés-Cabau J, Salaun E.. Percutaneous Transcatheter Edge-to-Edge Mitral Valve Repair With MitraClip System in the Era of G4.. Struct Heart 2022; 7(2):100114.
Pompeu Sa M, Van den Eynde J, Erten O, Caldonazo T, Doenst T, Marin-Cuartas M, Borger MA, Clavel MA, Pibarot P, Rodriguez R, Ramlawi B, Goldman S.. Coaptation Length as Predictor of Recurrent Mitral Regurgitation After Surgical Repair for Degenerative Mitral Valve Disease: Meta-Analysis of Reconstructed Time-to-Event Data.. Struct Heart 2023; 7(3):100152.
Jean G, Mogensen NSB, Clavel MA. Aortic Valvular Stenosis and Heart Failure: Advances in Diagnostic, Management, and Intervention.. Heart Fail Clin 2023; 19(3):273-283.
Ash J, Sandhu GS, Arriola-Montenegro J, Agakishiev D, Clavel MA, Pibarot P, Duval S, Nijjar PS. Performance of Computed Tomographic Angiography-Based Aortic Valve Area for Assessment of Aortic Stenosis.. J Am Heart Assoc 2023; 12(16):e029973.
Sá MP, Jacquemyn X, Van den Eynde J, Tasoudis P, Dokollari A, Torregrossa G, Sicouri S, Clavel MA, Pibarot P, Ramlawi B. Impact of Prosthesis-Patient Mismatch After Transcatheter Aortic Valve Replacement: Meta-Analysis of Kaplan-Meier-Derived Individual Patient Data.. JACC Cardiovasc Imaging 2023; 16(3):298-310.
Powers A, Clavel MA. Calcium Scoring to Classify Aortic Valve Stenosis Severity: What Is the Current Data?. Curr Cardiol Rep 2023; 25(9):1095-1101.
Bernard J, Jean G, Bienjonetti-Boudreau D, Jacques F, Tastet L, Salaun E, Clavel MA. Prognostic utility of N-terminal pro B-type natriuretic peptide ratio in mixed aortic valve disease.. Open Heart 2023; 10(2):e002361.
Bernard J, Georges G, Hecht S, Pibarot P, Clavel MA, Babaki S, Kalavrouziotis D, Mohammadi S. Mid-term clinical and echocardiographic results of the INSPIRIS RESILIA aortic valve: a retrospective comparison to the Magna Ease.. Interdiscip Cardiovasc Thorac Surg 2023; 37(1):ivad117.
Bernard J, Kalavrouziotis D, Salaun E, Babaki S, Clavel MA, Rodés-Cabau J, Pibarot P, Mohammadi S. Long-term echocardiographic data, mechanisms of failure, and reintervention outcomes of the Epic valve in mitral position-a large observational cohort.. J Thorac Cardiovasc Surg 2023; 166(6):1644-1655.e7.
Li Z, Zhang B, Salaun E, Côté N, Mahjoub H, Mathieu P, Dahou A, Zenses AS, Xu Y, Pibarot P, Wu Y, Clavel MA. Association Between Remnant Cholesterol and Progression of Bioprosthetic Valve Degeneration.. Eur Heart J Cardiovasc Imaging 2023; 24(12):1690-1699.
Sá MP, Jacquemyn X, Van den Eynde J, Serna-Gallegos D, Chu D, Clavel MA, Pibarot P, Sultan I. Midterm Survival of Low-Risk Patients Treated With Transcatheter Versus Surgical Aortic Valve Replacement: Meta-Analysis of Reconstructed Time-to-Event Data.. J Am Heart Assoc 2023; 12(21):e030012.
Pibarot P, Clavel MA.. Low-Gradient Aortic Stenosis with Preserved Left Ventricular Ejection Fraction: Setting the Record Straight.. JACC Adv 2023; 2(2):100263.
Sá MP, Van den Eynde J, Simonato M, Hirji S, Erten O, Jacquemyn X, Tasoudis P, Dokollari A, Sicouri S, Weymann A, Ruhparwar A, Arora R, Clavel MA, Pibarot P, Ramlawi B. Late outcomes of valve-in-valve transcatheter aortic valve implantation versus re-replacement: Meta-analysis of reconstructed time-to-event data.. Int J Cardiol 2023; 370(0):112-121.
Sá MP, Jacquemyn X, Van den Eynde J, Tasoudis P, Erten O, Sicouri S, Macedo FY, Pasala T, Kaple R, Weymann A, Ruhparwar A, Clavel MA, Pibarot P, Ramlawi B. Impact of Paravalvular Leak on Outcomes After Transcatheter Aortic Valve Implantation: Meta-Analysis of Kaplan-Meier-derived Individual Patient Data.. Struct Heart 2023; 7(2):100118.
Sá MP, Jacquemyn X, Van den Eynde J, Pibarot P, Clavel MA. Reply: Causal Inference on Avoiding Prosthesis-Patient Mismatch.. JACC Cardiovasc Imaging 2023; 16(9):1245-1246.
Ye Z, Clavel MA, Foley TA, Pibarot P, Enriquez-Sarano M, Michelena HI. Computed tomography calcium scoring in aortic stenosis: bicuspid versus tricuspid morphology.. Heart 2023; 0(0):Epub.
Sá MP, Jacquemyn X, Simonato M, Brown JA, Ahmad D, Serna-Gallegos D, Clavel MA, Pibarot P, Dvir D, Sultan I. Late Survival After Valve-in-Valve Transcatheter Aortic Valve Implantation With Balloon- Versus Self-Expandable Valves: Meta-Analysis of Reconstructed Time-to-Event Data.. Am J Cardiol 2023; 209(0):120-127.
Dweck MR, Loganath K, Bing R, Treibel TA, McCann GP, Newby DE, Leipsic J, Fraccaro C, Paolisso P, Cosyns B, Habib G, Cavalcante J, Donal E, Lancellotti P, Clavel MA, Otto CM, Pibarot P. Multi-modality imaging in aortic stenosis: an EACVI clinical consensus document.. Eur Heart J Cardiovasc Imaging 2023; 24(11):1430-1443.

Dr Marie-Annick Clavel

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