Domaine de recherche
Métabolisme et dommage musculaire chez l'obèse, le diabétique, et la personne active.
Description des travaux
Mes intérêts de recherche se situent au niveau des changements dans les muscles squelettiques et cardiaques dans plusieurs conditions, de la performance sportive à la sarcopénie. Les modifications morphologiques et métaboliques qui se produisent avec l'obésité, le diabète et l'entraînement, ainsi que les mécanismes qui en sont responsables, sont étudiés chez l'humain. D'intérêt particulier est la contribution de différents phénotypes musculaires à la résistance à l'insuline, plus spécifiquement le rôle des lipides intracellulaires dans cette condition.
Prix et distinctions
1- FRSQ, Chercheur-boursier «junior 2» (2005-2007).
Publications
60- Imbeault P, Tremblay A, Simoneau JA, Joanisse DR. Weight loss-induced rise in plasma pollutant is associated with reduced skeletal muscle oxidative capacity. Am J Physiol Endocrinol Metab 2002; 282(3):E574-9.
- Ukkola O, Joanisse DR, Tremblay A, Bouchard C. Na+-K+-ATPase alpha 2-gene and skeletal muscle characteristics in response to long-term overfeeding. J Appl Physiol 2003; 94(5):1870-4.
- Doucet E, Tremblay A, Simoneau JA, Joanisse DR. Skeletal muscle enzymes as predictors of 24-h energy metabolism in reduced-obese persons. Am J Clin Nutr 2003; 78(3):430-5.
- Hunter GR, Newcomer BR, Weinseir RL, Karapondo DL, Larson-Meyer DE, Joanisse DR, Bamman MM. Age is independently related to muscle metabolic capacity in premenopausal women.. J Appl Physiol 2002; 93(1):70-6.
- Sun G, Ukkola T, Rankinen T, Joanisse DR, Bouchard C. Skeletal muscle characteristics predict body fat gain in response to overfeeding in never-obese young men.. Metabolism 2002; 51(4):451-6.
- Rhéaume C, Waib PH, Kouamé N, Nadeau A, Lacoursière Y, Joanisse DR, Simoneau JA, Cléroux J. Effects of intense and prolonged exercise on glycogen metabolism, insulin sensivity and regional blood flow in hypertensive patients.. Circulation 2003; 108(0):2853-9.
- Bossé Y, Joanisse DR, Boulay MR. Modulations rédox de la contraction musculaire.. Science et motricité 2003; 50(0):7-31.
- Rico-Sanz J, Rankinen T, Joanisse DR, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C,. Associations between cardiorespiratory responses to exercise and the C34T AMPD1 gene polymorphism in the HERITAGE family study.. Physiol Genomics 2003; 14(0):161-6.
- Rico-Sanz J, Rankinen T, Joanisse DR, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Familial resemblance for muscle phenotypes in the HERITAGE family study.. Med Sci Sports Exerc 2003; 35(0):1360-6.
- Rosenbaum M, Vandenborne K, Goldsmith R, Simoneau JA, Heymsfield S, Joanisse DR, Hirsch J, Murphy E, Segal KR, Leibel RL. Effects of experimental weight perturbation on skeletal muscle fuel utilization and work efficiency.. Am J Physiol Regul Integr Comp Physiol 2003; 285(0):R183-92.
- Doucet M, Debigaré R, Joanisse DR, Côté C, LeBlanc P, Gregoire J, Deslauriers J, Vaillancourt R, Maltais F. Adaptation of the diaphragm and the vastus lateralis in mild-to-moderate COPD.. Eur Respir J 2004; 24(6):971-9.
- Tsuda K, Nishio I, Rhéaume C, Waib PH, Kouamé N, Lacoursière Y, Cléroux J, Nadeau A, Joanisse DR, Simoneau JA. Insulin sensivity, glucose metabolism, and membrane fluidity in hypertensive subjects.. Circulation 2004; 109(0):e225.
- Basset F, Joanisse DR, Boivin F, St-Onge J, Billaut F, Doré J, Chouinard R, Falgairette G, Richard D, Boulay MR. Effects of short-term normobaric hypoxia on haematology, muscle phenotypes, and physical performance in highly trained athletes.. Exp Physiol 2006; 91(0):391-402.
- Dubé MC, Joanisse DR, Prud'Homme D, Lemieux S, Bouchard C, Pérusse L, Lavoir C, Weisnagel SJ. Muscle adiposity and body fat distribution in type 1 and type 2 diabetes: varying relationships according to diabetes type.. Int J Obes (Lond) 2006; 30(0):1721-8.
- Joanisse DR, Tremblay A. Calcium intake, body composition and plasma lipid-lipoprotein concentrations in adults.. Australian Journal of Dairy Technology 2005; 60(0):66-69.
- Hunter GR, Bamman MM, Larson-Meyer DE, Joanisse DR, McCarthy JP, Blaudeau TE, Newcomer BR. Inverse relationship between exercice economy and oxydative capacity in muscle.. Eur J Appl Physiol 2005; 94(5):558-68.
- Malenfant P, Joanisse DR, Theriault R, Goodpaster BH, Kelley DE, Simoneau JA. Fat content in individual muscle fibers of lean and obese subjects.. Int J Obes Relat Metab Disord 2001; 25(9):1316-21.
- Malenfant P, Tremblay A, Doucet E, Imbeault P, Simoneau JA, Joanisse DR. Elevated intramyocellular lipid concentration in obese subjects is not reduced after diet and exercise training.. Am J Physiol Endocrinol Metab 2001; 280(4):E632-9.
- Berthiaume M, Laplante M, Festuccia WT, Cianflone K, Turcotte LP, Joanisse DR, Olivecrona G, Thieringer R, Deshaies Y. 11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues.. Am J Physiol Endocrinol Metab 2007; 293(4):E1045-52.
- Doucet M, Russell AP, Léger B, Debigaré R, Joanisse DR, Caron MA, LeBlanc P, Maltais F. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.. Am J Respir Crit Care Med 2007; 176(3):261-9.
- Roy C, Paglialunga S, Fisette A, Schrauwen P, Moonen-Kornips E, St-Onge J, Hesselink MK, Richard D, Joanisse DR, Cianflone K. Shift in metabolic fuel in Acylation Stimulating Protein (ASP)-deficient mice following a high-fat diet.. Am J Physiol Endocrinol Metab 2008; 294(6):E1051-9.
- Metz L, Mercier J, Tremblay A, Alméras N, Joanisse DR. Effect of weight loss on lactate transporter expression in skeletal muscle of obese subjects.. J Appl Physiol 2008; 104(3):633-8.
- Berthiaume M, Laplante M, Festuccia W, Gélinas Y, Poulin S, Lalonde J, Joanisse DR, Thieringer R, Deshaies Y. Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1.. Endocrinology 2007; 148(5):2391-7.
- Guderley H, Joanisse DR, Mokas S, Bilodeau GM, Garland T Jr. Altered fibre types in gastrocnemius muscle of high wheel-running selected mice with mini-muscle phenotypes.. Comp Biochem Physiol B Biochem Mol Biol 2008; 149(3):490-500.
- Koska J, Stefan N, Permana PA, Weyer C, Sonoda M, Bogardus C, Smith SR, Joanisse DR, Funahashi T, Krakoff J, Bunt JC. Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals.. Am J Clin Nutr 2008; 87(2):295-302.
- Riou ME, Pigeon E, St-Onge J, Tremblay A, Marette A, Weisnagel SJ, Joanisse DR. Predictors of cardiovascular fitness in sedentary men.. Appl Physiol Nutr Metab 2009; 34(2):99-106.
- Pigeon E, Riou ME, St-Onge J, Couillard E, Tremblay A, Marette A, Weisnagel SJ, Joanisse DR. Validation of a simple index (SIisOGTT) of insulin sensitivity in a population of sedentary men.. Diabetes Metab 2009; 35(5):398-403.
- Riou ME, Pigeon E, St-Onge J, Tremblay A, Marette A, Weisnagel J, Joanisse DR. Cardiorespiratory Fitness and Components of the Metabolic Syndrome in Sedentary Men.. Obes Facts 2009; 2(5):318-324.
- Baillot RG, Joanisse DR, Stevens LM, Doyle DP, Dionne B, Lellouche F. Recent evolution in demographic and clinical characteristics and in-hospital morbidity in patients undergoing coronary surgery.. Can J Surg 2009; 52(5):394-400.
- Doucet M, Dubé A, Joanisse DR, Debigaré R, Michaud A, Paré MÈ, Vaillancourt R, Fréchette E, Maltais F. Atrophy and hypertrophy signalling of the quadriceps and diaphragm in COPD.. Thorax 2010; 65(11):963-70.
- Gilbert JA, Joanisse DR, Chaput JP, Miegueu P, Cianflone K, Alméras N, Tremblay A. Milk supplementation facilitates appetite control in obese women during weight loss: a randomised, single-blind, placebo-controlled trial.. Br J Nutr 2011; 105(1):133-43.
- Carvalho G, Pelletier P, Albacker T, Lachapelle K, Joanisse DR, Hatzakorzian R, Lattermann R, Sato H, Marette A, Schricker T. Cardioprotective Effects of Glucose and Insulin Administration While Maintaining Normoglycemia (GIN Therapy) in Patients Undergoing Coronary Artery Bypass Grafting.. J Clin Endocrinol Metab 2011; 96(5):1469-77.
- Riou ME, Pigeon E, St-Onge J, Tremblay A, Marette A, Weisnagel SJ, Joanisse DR. Cardiorespiratory fitness and components of the metabolic syndrome in sedentary men.. Obes Facts 2009; 2(5):318-24.
- Pigeon E, Couillard E, Tremblay A, Bouchard C, Weisnagel JS, Joanisse DR. Mid thigh subcutaneous adipose tissue and glucose tolerance in the Quebec Family Study.. Obes Facts 2008; 1(6):310-8.
- Pigeon E, Riou ME, St-Onge J, Couillard E, Tremblay A, Marette A, Weisnagel SJ, Joanisse DR. Validation of a simple index (SIIS OGTT) assessing insulin sensitivity in a population of sedentary men.. Diabetes Metab 2009; 35(5):398-403.
- Joseph AM, Joanisse DR, Baillot RG, Hood DA.. Mitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions.. Exp Diabetes Res 2012; 2012(0):642038.
- Pigeon E, Riou ME, St-Onge J, Couillard E, Tremblay A, Marette A, Weisnagel SJ, Joanisse DR. Validation of a simple index (SIIS OGTT) assessing insulin sensitivity in a population of sedentary men.. Diabetes Metab 2009; 35(5):398-403.
- Billaut F, Joanisse DR, Basset FA.. Anthropometric characteristics account for time to exhaustion in cycling.. Int J Sports Med 2014; 35(13):1084-9.
- Huth C, Dubois MJ, Marette A, Tremblay A, Weisnagel SJ, Lacaille M, Mauriège P, Joanisse DR.. Irisin is more strongly predicted by muscle oxidative potential than adiposity in non-diabetic men.. J Physiol Biochem 2015; 71(3):559-68.
- Mauriège P, Joanisse DR, CasparBauguil S, Cartier A, Lemieux I, Bergeron J, Biron S, Marceau P, Richard D. Gene expression of different adipose tissues of severely obese women with or without a dysmetabolic profile.. J Physiol Biochem 2015; 71(4):719-32.
- Mauriège P, Joanisse DR, Cartier A, Lemieux I, Bergeron J, Biron S, Marceau P, Richard D.. Gene expression in a rarely studied intraabdominal adipose depot, the round ligament, in severely obese women: A pilot study.. Adipocyte 2015; 5(1):27-34.
- Paradis-Deschênes P, Joanisse DR, Billaut F. Ischemic preconditioning increases muscle perfusion, oxygen uptake, and force in strength-trained athletes.. Appl Physiol Nutr Metab 2016; 41(9):938-44.
- Jabbour G, Mauriege P, Joanisse D, Iancu HD. Effect of supramaximal exercise training on metabolic outcomes in obese adults.. J Sports Sci 2017; 35(20):1975-1981.
- Jabbour G, Iancu HD, Mauriège P, Joanisse DR, Martin LJ. High-intensity interval training improves performance in young and older individuals by increasing mechanical efficiency.. Physiol Rep 2017; 5(7):13232.
- Paradis-Deschênes P, Joanisse DR, Billaut F.. Sex-Specific Impact of Ischemic Preconditioning on Tissue Oxygenation and Maximal Concentric Force.. Front Physiol 2017; 7(0):674.
- Jabbour G, Iancu HD, Zouhal H, Mauriège P, Joanisse DR, Martin LJ. High-intensity interval training improves acute plasma volume responses to exercise that is age dependent.. Physiol Rep 2018; 6(4):Epub.
- Paradis-Deschênes P, Joanisse DR, Billaut F. Ischemic Preconditioning Improves Time Trial Performance at Moderate Altitude.. Med Sci Sports Exerc 2018; 50(3):533-541.
- Paradis-Deschênes P, Joanisse DR, Billaut F. Response.. Med Sci Sports Exerc 2018; 50(12):2613.
- Desmarais F, Bergeron KF, Lacaille M, Lemieux I, Bergeron J, Biron S, Rassart E, Joanisse DR, Mauriege P, Mounier C. High ApoD protein level in the round ligament fat depot of severely obese women is associated with an improved inflammatory profile.. Endocrine 2018; 61(2):248-257.
- Clément AA, Riesco E, Tessier S, Lacaille M, Pérusse F, Coté M, Després JP, Weisnagel J, Doré J, Joanisse DR, Mauriège P.. The relationship between adiposopathy and glucose-insulin homeostasis is not affected by moderate-intensity aerobic training in healthy women with obesity.. J Physiol Biochem 2018; 74(4):591-601.
- Clément AA, Joanisse DR, Mauriège P. Le phénotype d'obésité sans anomalies métaboliques: un état transitoire?. Obesity (Silver Spring) 2018; 13(0):17-26.
- Alsubheen SA, Ismail M, Baker A, Blair J, Adebayo A, Kelly L, Chandurkar V, Cheema S, Joanisse DR, Basset FA.. The effects of diurnal Ramadan fasting on energy expenditure and substrate oxidation in healthy men.. Br J Nutr 2017; 118(12):1023-1030.
- Garnier S, Joffroy S, Hérédia C, Joanisse DR, Mauriège P.. Comparison of health benefits between a high intensity interval training and a moderate intensity continuous training when performed in a non-laboratory setting, in moderately obese women.. Int J Phys Educ Fitness Sports 2018; 7(2):43-56.
- Paradis-Deschênes P, Lapointe J, Joanisse DR, Billaut F. Similar Recovery of Maximal Cycling Performance after Ischemic Preconditioning, Neuromuscular Electrical Stimulation or Active Recovery in Endurance Athletes.. J Sports Sci Med 2020; 19(4):761-771.
- Mauriège P, Karelis AD, Taleb N, Clément AA, Joanisse DR. Comparing an adiposopathy approach with four popular classifications schemes to categorize the metabolic profile of postmenopausal women.. J Physiol Biochem 2020; 76(4):609-622.
- Paradis-Deschênes P, Joanisse DR, Mauriège P, Billaut F. Ischemic Preconditioning Enhances Aerobic Adaptations to Sprint-Interval Training in Athletes Without Altering Systemic Hypoxic Signaling and Immune Function.. Front Sports Act Living 2020; 2(0):41.
- Clément AA, Lacaille M, Lounis MA, Biertho LD, Richard D, Lemieux I, Bergeron J, Mounier C, Joanisse DR, Mauriège P. Intra-abdominal adipose depot variation in adipogenesis, lipogenesis, angiogenesis, and fibrosis gene expression and relationships with insulin resistance and inflammation in premenopausal women with severe obesity.. J Physiol Biochem 2022; 78(2):527-542.
- Tremblay EJ, Tchernof A, Pelletier M, Chabot N, Joanisse DR, Mauriège P. Contribution of markers of adiposopathy and adipose cell size in predicting insulin resistance in women of varying age and adiposity.. Adipocyte 2022; 11(1):175-189.
- Peyrel P, Mauriège P, Frenette J, Laflamme N, Greffard K, Huth C, Bergeron J, Joanisse DR.. Statin withdrawal and health-related quality of life in a primary cardiovascular prevention cohort.. Qual Life Res 2023; 32(7):1943-1954.
- Peyrel P, Mauriège P, Frenette J, Laflamme N, Greffard K, Dufresne SS, Huth C, Bergeron J, Joanisse DR. Impact of statin withdrawal on perceived and objective muscle function.. PLoS One 2023; 18(6):e0281178.
