- Accueil
- Chercheurs
- Dr Cristoforo Silvestri
Chercheur(e)
Dr Cristoforo Silvestri
Obésité-Métabolisme
A3148
Publications
36- Mela V, Piscitelli F, Berzal AL, Chowen J, Silvestri C, Viveros MP, Di Marzo V.. Sex-dependent effects of neonatal maternal deprivation on endocannabinoid levels in the adipose tissue: influence of diet.. J Physiol Biochem 2017; 0(0):Epub.
- Janssens A, Silvestri C, Martella A, Vanoevelen JM, Di Marzo V, Voets T. Delta9-tetrahydrocannabivarin impairs epithelial calcium transport through inhibition of TRPV5 and TRPV6.. Pharmacol Res 2018; 136(0):83-89.
- Ligresti A, Silvestri C, Vitale RM, Martos J, Piscitelli F, Wang J, Allarà M, Carling R, Luongo L, Guida F, Illiano A, Amoresano A, Maione S, Amodeo P, Woodward D, Di Marzo V, Marino G. FAAH-catalyzed C-C bond cleavage of a new multi-target analgesic drug.. ACS Chem Neurosci 2019; 10(1):424-437.
- Piscitelli F, Silvestri C. Role of the Endocannabinoidome in Human and Mouse Atherosclerosis.. Curr Pharm Des 2019; 25(29):3147-3164.
- Vitale RM, D'Aniello E, Gorbi S, Martella A, Silvestri C, Giuliani ME, Fellous T, Gentile A, Carbone M, Cutignano A, Grauso L, Magliozzi L, Polese G, D'Aniello B, Defranoux F, Felline S, Terlizzi A, Calignano A, Regoli F, Di Marzo V, Amodeo P, Mollo E. Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest.. Mar Drugs 2018; 16(11):E431.
- Manca C, Boubertakh B, Leblanc N, Deschênes T, Lacroix S, Martin C, Houde A, Veilleux A, Flamand N, Muccioli GG, Raymond F, Cani PD, Di Marzo V, Silvestri C. Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling.. J Lipid Res 2020; 61(1):70-85.
- Silvestri C, Pagano E, Lacroix S, Venneri T, Cristiano C, Calignano A, Parisi OA, Izzo AA, Di Marzo V, Borrelli F. Fish Oil, Cannabidiol and the Gut Microbiota: An Investigation in a Murine Model of Colitis.. Front Pharmacol 2020; 11(0):585096.
- Manca C, Shen M, Boubertakh B, Martin C, Flamand N, Silvestri C, Di Marzo V. Alterations of brain endocannabinoidome signaling in germ-free mice.. Biochim Biophys Acta Mol Cell Biol Lipids 2020; 1865(12):158786.
- Lefort C, Roumain M, Van Hul M, Rastelli M, Manco R, Leclercq I, Delzenne NM, Di Marzo V, Flamand N, Luquet S, Silvestri C, Muccioli GG, Cani PD. Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism.. Cells 2020; 9(5):1247.
- Dione N, Lacroix S, Taschler U, Deschênes T, Abolghasemi A, Leblanc N, Di Marzo V, Silvestri C. Mgll Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota.. Cells 2020; 9(12):2705.
- Suriano F, Manca C, Flamand N, Depommier C, Van Hul M, Delzenne NM, Silvestri C, Cani PD, Di Marzo V.. Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota.. Biochim Biophys Acta Mol Cell Biol Lipids 2021; 1867(1):159056.
- Archambault AS, Tinto F, Dumais É, Rakotoarivelo V, Kostrzewa M, Plante PL, Martin C, Simard M, Silvestri C, Pouliot R, Laviolette M, Boulet LP, Vitale RM, Ligresti A, Di Marzo V, Flamand N.. Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils.. Cells 2021; 10(9):2322.
- Depommier C, Vitale RM, Iannotti FA, Silvestri C, Flamand N, Druart C, Everard A, Pelicaen R, Maiter D, Thissen JP, Loumaye A, Hermans MP, Delzenne NM, de Vos WM, Di Marzo V, Cani PD. Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPAR? Agonists.. Cells 2021; 10(1):185.
- Shen M, Manca C, Suriano F, Nallabelli N, Pechereau F, Allam-Ndoul B, Iannotti FA, Flamand N, Veilleux A, Cani PD, Silvestri C, Di Marzo V. Three of a Kind: Control of the Expression of Liver-Expressed Antimicrobial Peptide 2 (LEAP2) by the Endocannabinoidome and the Gut Microbiome.. Molecules 2021; 27(1):1.
- Abolghasemi A, Manca C, Iannotti FA, Shen M, Leblanc N, Lacroix S, Martin C, Flamand N, Di Marzo V, Silvestri C. Assessment of the Effects of Dietary Vitamin D Levels on Olanzapine-Induced Metabolic Side Effects: Focus on the Endocannabinoidome-Gut Microbiome Axis.. Int J Mol Sci 2021; 22(22):12361.
- Ayoub SM, Piscitelli F, Silvestri C, Limebeer CL, Rock EM, Smoum R, Farag M, de Almeida H, Sullivan MT, Lacroix S, Boubertakh B, Nallabelli N, Lichtman AH, Leri F, Mechoulam R, Di Marzo V, Parker LA. Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in N-Oleoylglycine and N-Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators.. Front Pharmacol 2021; 12(0):706703.
- Manca C, Lacroix S, Pérusse F, Flamand N, Chagnon Y, Drapeau V, Tremblay A, Di Marzo V, Silvestri C. Oral Capsaicinoid Administration Alters the Plasma Endocannabinoidome and Fecal Microbiota of Reproductive-Aged Women Living with Overweight and Obesity.. Biomedicines 2021; 9(9):1246.
- Forte N, Roussel C, Marfella B, Lauritano A, Villano R, De Leonibus E, Salviati E, Khalilzadehsabet T, Giorgini G, Silvestri C, Piscitelli F, Pina Mollica M, Di Marzo V, Cristino L.. Olive oil-derived endocannabinoid-like mediators inhibit palatable food-induced reward and obesity.. Commun Biol 2023; 6(1):959.
- Bertrand JA, Woodward DF, Sherwood JM, Spenlehauer A, Silvestri C, Piscitelli F, Di Marzo V, Yamazaki M, Sakimura K, Inoue Y, Watanabe K, Overby DR.. Deletion of the gene encoding prostamide/prostaglandin F synthase reveals an important role in regulating intraocular pressure.. Prostaglandins Leukot Essent Fatty Acids 2021; 165(0):102235.
- Suriano F, Manca C, Flamand N, Depommier C, Van Hul M, Delzenne NM, Silvestri C, Cani PD, Di Marzo V. Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota.. Biochim Biophys Acta Mol Cell Biol Lipids 2022; 1867(1):159056.
- Ben Necib R, Manca C, Lacroix S, Martin C, Flamand N, Di Marzo V, Silvestri C. Hemp seed significantly modulates the endocannabinoidome and produces beneficial metabolic effects with improved intestinal barrier function and decreased inflammation in mice under a high-fat, high-sucrose diet as compared with linseed.. Front Immunol 2022; 13(0):882455.
- Roussel C, Anunciação Braga Guebara S, Plante PL, Desjardins Y, Di Marzo V, Silvestri C. Short-term supplementation with ?-3 polyunsaturated fatty acids modulates primarily mucolytic species from the gut luminal mucin niche in a human fermentation system.. Gut Microbes 2022; 14(1):2120344.
- Boubertakh B, Silvestri C, Di Marzo V. Obesity: The Fat Tissue Disease Version of Cancer.. Cells 2022; 11(12):1872.
- Borrelli F, Esposito G, Montmayeur JP, Silvestri C.. Editorial: Implications of gut-brain interactions for the effects of compounds derived from Cannabis or modulating the endocannabinoid system in physiological and pathological processes.. Front Cell Neurosci 2022; 16(0):1042821.
- Boubertakh B, Courtemanche O, Marsolais D, Di Marzo V, Silvestri C.. New role for the anandamide metabolite prostaglandin F2α ethanolamide: Rolling preadipocyte proliferation.. J Lipid Res 2023; 64(11):100444.
- Bertrand JA, Woodward DF, Sherwood JM, Spenlehauer A, Silvestri C, Piscitelli F, Di Marzo V, Yamazaki M, Sakimura K, Watanabe K, Overby DR.. Gene deletion studies reveal a critical role for prostamide/prostaglandin F2α synthase in prostamide F2α formation.. bioRxiv 2020; 0(0):Epub.
- Kalkan H, Pagano E, Paris D, Panza E, Cuozzo M, Moriello C, Piscitelli F, Abolghasemi A, Gazzerro E, Silvestri C, Capasso R, Motta A, Russo R, Di Marzo V, Iannotti FA. Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy.. EMBO Mol Med 2023; 0(0):e16225.
- Suriano F, Manca C, Flamand N, Van Hul M, Delzenne NM, Silvestri C,Cani PD, Di Marzo V.. A Lipidomics- and Transcriptomics-Based Analysis of the Intestine of Genetically Obese ( ob/ob) and Diabetic (db/db) Mice: Links with Inflammation and Gut Microbiota. Cells 2023; 12(3):411.
- Mukorako P, St-Pierre DH, Flamand N, Biertho L, Lebel S, Lemoine N, Plamondon J, Roy MC, Tchernof A, Varin TV, Marette A, Silvestri C, Di Marzo V, Richard D. Hypoabsorptive surgeries cause limb-dependent changes in the gut endocannabinoidome and microbiome in association with beneficial metabolic effects.. Int J Obes (Lond) 2023; 47(7):630-641.
- Lacroix S, Leblanc N, Abolghasemi A, Paris-Robidas S, Martin C, Frappier M, Flamand N, Silvestri C, Raymond F, Millette M, Di Marzo V, Veilleux A. Probiotic interventions promote metabolic health in high fat-fed hamsters in association with gut microbiota and endocannabinoidome alterations.. Benef Microbes 2023; 0(0):1-16.
- Venneri T, Giorgini G, Leblanc N, Flamand N, Borrelli F, Silvestri C, Di Marzo V. Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice.. Lipids Health Dis 2023; 22(1):63.
- Silvestri C, Di Marzo V. The Gut Microbiome-Endocannabinoidome Axis: A New Way of Controlling Metabolism, Inflammation, and Behavior.. Function (Oxf) 2023; 4(2):zqad003.
- Daniel N, Le Barz M, Mitchell PL, Varin TV, Julien IB, Farabos D, Pilon G, Gauthier J, Garofalo C, Kang JX, Trottier J, Barbier O, Roy D, Chassaing B, Levy E, Raymond F, Lamaziere A, Flamand N, Silvestri C, Jobin C, Di Marzo V, Marette A. Comparing Transgenic Production to Supplementation of ?-3 PUFA Reveals Distinct But Overlapping Mechanisms Underlying Protection Against Metabolic and Hepatic Disorders.. Function (Oxf) 2023; 4(2):zqac069.
- Inserra A, Giorgini G, Lacroix S, Bertazzo A, Choo J, Markopolous A, Grant E, Abolghasemi A, De Gregorio D, Flamand N, Rogers G, Comai S, Silvestri C, Gobbi G, Di Marzo V. Effects of repeated lysergic acid diethylamide (LSD) on the mouse brain endocannabinoidome and gut microbiome.. Br J Pharmacol 2023; 180(6):721-739.
- Forte N, Roussel C, Marfella B, Lauritano A, Villano R, De Leonibus E, Salviati E, Khalilzadehsabet T, Giorgini G, Silvestri C, Piscitelli F, Mollica MP, Di Marzo V, Cristino L. Olive oil-derived endocannabinoid-like mediators inhibit palatable food-induced reward and obesity.. Commun Biol 2023; 6(1):959.
- Boubertakh B, Courtemanche O, Marsolais D, Di Marzo V, Silvestri C. New role for the anandamide metabolite prostaglandin F(2?) ethanolamide: Rolling preadipocyte proliferation.. J Lipid Res 2023; 0(0):100444.