Chercheur(e)

Dr Jean-Pierre Després

Cardiologie

Y2137

jean-pierre.despres@criucpq.ulaval.ca

Domaine de recherche

Obésité, distribution du tissu adipeux, obésité viscérale, résistance à l'insuline, syndrome métabolique, diabète de type 2, risque cardiométabolique global, facteurs de risque cardiovasculaires, lipides, lipoprotéines, traitement pharmacologique, prévention primaire et secondaire, activité physique, exercice, nutrition.

Description des travaux

L'équipe de recherche du Dr Jean-Pierre Després étudie les mécanismes impliqués dans l'association entre l'obésité, l'accumulation de tissu adipeux viscéral et une agglomération d'altérations métaboliques comprenant la résistance à l'insuline, une dyslipidémie athérogène et un profil prothrombogène et inflammatoire. Des travaux de nature épidémiologique et des études métaboliques sont réalisés chez l'humain afin de mieux comprendre les facteurs et les mécanismes impliqués dans le développement du diabète de type 2 et des maladies cardiovasculaires, complications cliniques fréquentes de l'obésité viscérale et de la présence d'un syndrome métabolique. Ces travaux ont permis l'identification de nouveaux marqueurs de risque, améliorant ainsi l'identification et la prise en charge des individus à risque élevé de maladie coronarienne. Par ailleurs, de nombreux travaux conduits dans le laboratoire du Dr Després visent à évaluer l'impact de la prise en charge de l'obésité à risque (obésité viscérale) par de meilleures habitudes de vie (telles que la pratique régulière d'activité physique et une alimentation saine) et, si nécessaire, par pharmacothérapie sur l'ensemble des complications diabétogènes et athérogènes. Ces travaux ont donc un impact significatif sur la santé d'une proportion sans cesse croissante de notre population confrontée à un environnement « toxique » de sédentarité, à une alimentation inadéquate de pauvre qualité et dense en calories générant une épidémie d'obésité, de diabète de type 2 et de maladies cardiovasculaires.

Prix et distinctions

Janvier 2014 : Membre de l’Académie des Grands Québécois, Chambre de commerce et d’industrie de Québec
Juin 2012 : D. Bruce Dill Historical Lecture, American College of Sports Medicine
Décembre 2011 : Chercheur le plus productif dans le domaine de la recherche sur le syndrome métabolique au cours des 10 dernières années (sur 110 000 chercheurs), Thomson Reuters ScienceWatch
Janvier 2011 : Prix Grands diplômés (Médaille Gloire de l’Escolle), Association des diplômés de l’Université Laval
Janvier 2011 : Grand lauréat 2010 Le Soleil-Radio-Canada
Août 2010 : Troisième chercheur le plus productif dans le domaine de la recherche sur l’obésité au cours des 10 dernières années (sur 173 000 chercheurs), Thomson Reuters ScienceWatch
Janvier 2010 : Prix Adrien-Pouliot, Association francophone pour le savoir (ACFAS)
Janvier 2008 : Prix Coeur Québec Argent, Fondation des maladies du coeur du Québec
Janvier 1999 : Eli Lilly Career Award, North American Association for the Study of Obesity (NAASO)
1999 : Harold-Segall Award, Société canadienne de cardiologie

Publications

502

Trier par année :

Bossé Y, Pascot A, Dumont M, Brochu M, Prud'homme D, Bergeron J, Després JP, Vohl MC. Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil.. Genet Med 2002; 4(4):311-5.
Bossé Y, Vohl MC, Dumont M, Brochu M, Bergeron J, Després JP, Prud'homme D. Influence of the angiotensin-converting enzyme gene insertion/deletion polymorphism on lipoprotein/lipid response to gemfibrozil.. Clin Genet 2002; 62(1):45-52.
Cantin B, Després JP, Lamarche B, Moorjani S, Lupien PJ, Bogaty P, Bergeron J, Dagenais GR. Association of fibrinogen and lipoprotein(a) as a coronary heart disease risk factor in men (The Quebec Cardiovascular Study). Am J Cardiol 2002; 89(6):662-6.
Cantin B, Lamarche B, Després JP, Dagenais GR. Does correction of the friedewald formula using lipoprotein(a) change our estimation of ischemic heart disease risk? The Quebec Cardiovascular Study.. Atherosclerosis 2002; 163(2):261-7.
Couillard C, Bergeron N, Pascot A, Alméras N, Bergeron J, Tremblay A, Prud'homme D, Després JP. Evidence for impaired lipolysis in abdominally obese men: postprandial study of apolipoprotein B-48- and B-100-containing lipoproteins.. Am J Clin Nutr 2002; 76(2):311-8.
Couillard C, Mauriège P, Prud'homme D, Nadeau A, Tremblay A, Bouchard C, Després JP. Plasma leptin response to an epinephrine infusion in lean and obese women. Obes Res 2002; 10(1):6-13.
Doucet E, St-Pierre S, Alméras N, Imbeault P, Mauriège P, Pascot A, Després JP, Tremblay A. Reduction of visceral adipose tissue during weight loss.. Eur J Clin Nutr 2002; 56(4):297-304.
Imbeault P, Chevrier J, Dewailly E, Ayotte P, Després JP, Mauriège P, Tremblay A. Increase in plasma pollutant levels in response to weight loss is associated with the reduction of fasting insulin levels in men but not in women. Metabolism 2002; 51(4):482-6.
Pelletier C, Després JP, Tremblay A. Plasma organochlorine concentrations in endurance athletes and obese individuals. Med Sci Sports Exerc 2002; 34(12):1971-5.
Lemieux I, Alméras N, Mauriège P, Blanchet C, Dewailly E, Bergeron J, Després JP. Prevalence of "hypertriglyceridemic waist" in men who participated in the Quebec Health Survey: association with atherogenic and diabetogenic metabolic risk factors.. Can J Cardiol 2002; 18(7):725-32.
Pirro M, Mauriège P, Tchernof A, Cantin B, Dagenais GR, Després JP, Lamarche B. Plasma free fatty acid levels and the risk of ischemic heart disease in men: prospective results from the Québec Cardiovascular Study.. Atherosclerosis 2002; 160(2):377-84.
Lemieux I, Pascot A, Lamarche B, Prud'homme D, Nadeau A, Bergeron J, Després JP. Is the gender difference in LDL size explained by the metabolic complications of visceral obesity?. Eur J Clin Invest 2002; 32(12):909-17.
Lemieux I, Houde I, Pascot A, Lachance JG, Noël R, Radeau T, Després JP, Bergeron J. Effects of prednisone withdrawal on the new metabolic triad in cyclosporine-treated kidney transplant patients.. Kidney Int 2002; 62(5):1839-47.
St-Pierre J, Lemieux I, Vohl MC, Perron P, Tremblay G, Després JP, Gaudet D. Contribution of abdominal obesity and hypertriglyceridemia to impaired fasting glucose and coronary artery disease. Am J Cardiol 2002; 90(1):15-8.
Després JP, Lemieux I, Salomon H, Delaval D. Effects of micronized fenofibrate versus atorvastatin in the treatment of dyslipidaemic patients with low plasma HDL-cholesterol levels: a 12-week randomized trial.. J Intern Med 2002; 251(6):490-9.
Rice T, Després JP, Pérusse L, Hong Y, Province MA, Bergeron J, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Familial aggregation of blood lipid response to exercise training in the health, risk factors, exercise training, and genetics (HERITAGE) Family Study.. Circulation 2002; 105(16):1904-8.
Lemieux I, Laperrière L, Dzavik V, Tremblay G, Bourgeois J, Després JP. A 16-week fenofibrate treatment increases LDL particle size in type IIA dyslipidemic patients. Atherosclerosis 2002; 162(2):363-71.
Ruel IL, Gaudet D, Perron P, Pascot A, Després JP, Bergeron J, Julien P, Lamarche B. Determinants of HDL particle size in patients with the null (P207L) or defective (D9N) mutation in the lipoprotein lipase gene: the Québec LipD Study.. Atherosclerosis 2002; 162(2):269-76.
Engert JC, Vohl MC, Williams SM, Lepage P, Loredo-Osti JC, Faith J, Doré C, Renaud Y, Burtt NP, Villeneuve A, Hirschhorn JN, Altshuler D, Groop LC, Després JP, Gaudet D, Hudson TJ. 5' flanking variants of resistin are associated with obesity.. Diabetes 2002; 51(5):1629-34.
Pascot A, Lemieux I, Bergeron J, Tremblay A, Nadeau A, Prud'homme D, Couillard C, Lamarche B, Després JP. HDL particle size: a marker of the gender difference in the metabolic risk profile. Atherosclerosis 2002; 160(2):399-406.
St-Pierre J, Lemieux I, Miller-Felix I, Prud'homme D, Bergeron J, Gaudet D, Nadeau A, Despres JP, Vohl MC. Visceral obesity and hyperinsulinemia modulate the impact of the microsomal triglyceride transfer protein -493G/T polymorphism on plasma lipoprotein levels in men.. Atherosclerosis 2002; 160(2):317-24.
Robins SJ, Despres JP,. MRC/BHF Heart Protection Study.. Lancet 2002; 360(9347):1780; auth.
Després JP, Lemieux I, Pascot A, Alméras N, Dumont M, Nadeau A, Bergeron J, Prud'homme D. Gemfibrozil reduces plasma C-reactive protein levels in abdominally obese men with the atherogenic dyslipidemia of the metabolic syndrome.. Arterioscler Thromb Vasc Biol 2003; 23(4):702-3.
Doucet E, Imbeault P, St-Pierre S, Alméras N, Mauriège P, Després JP, Bouchard C, Tremblay A. Greater than predicted decrease in energy expenditure during exercise after body weight loss in obese men.. Clin Sci (Lond) 2003; 105(1):89-95.
Couillard C, Vohl MC, Engert JC, Lemieux I, Houde A, Alméras N, Prud'homme D, Nadeau A, Després JP, Bergeron J. Effect of apoC-III gene polymorphisms on the lipoprotein-lipid profile of viscerally obese men.. J Lipid Res 2003; 44(5):986-93.
Scarsella C, Alméras N, Mauriège P, Blanchet C, Sauvé L, Dewailly E, Bergeron J, Després JP. Prevalence of metabolic alterations predictive of cardiovascular disease risk in the Québec population.. Can J Cardiol 2003; 19(1):51-7.
Sniderman AD, St-Pierre AC, Cantin B, Dagenais GR, Després JP, Lamarche B. Concordance/discordance between plasma apolipoprotein B levels and the cholesterol indexes of atherosclerotic risk.. Am J Cardiol 2003; 91(10):1173-7.
St-Pierre AC, Bergeron J, Pirro M, Cantin B, Dagenais GR, Després JP, Lamarche B,. Effect of plasma C-reactive protein levels in modulating the risk of coronary heart disease associated with small, dense, low-density lipoproteins in men (The Quebec Cardiovascular Study).. Am J Cardiol 2003; 91(5):555-8.
Mauriège P, Martel C, Langin D, Lacaille M, Després JP, Bélanger A, Labrie F, Deshaies Y. Chronic effects of dehydroepiandrosterone on rat adipose tissue metabolism.. Metabolism 2003; 52(3):264-72.
Després JP. Inflammation and cardiovascular disease: is abdominal obesity the missing link?. Int J Obes Relat Metab Disord 2003; 27(0):S22-4.
Couillard C, Bergeron J, Després JP, Gagnon J, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Apolipoprotein AI- and AI:AII-containing lipoproteins in white men and women of the HERITAGE Family study: Associations with metabolic risk profile variables.. Metabolism 2003; 52(12):1530-6.
Desmeules A, Couillard C, Tchernof A, Bergeron J, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Després JP, Bouchard C. Post-heparin lipolytic enzyme activities, sex hormones and sex hormone-binding globulin (SHBG) in men and women: The HERITAGE Family Study.. Atherosclerosis 2003; 171(2):343-50.
Blackburn P, Lamarche B, Couillard C, Pascot A, Bergeron N, Prud'homme D, Tremblay A, Bergeron J, Lemieux I, Després JP. Postprandial hyperlipidemia: another correlate of the "hypertriglyceridemic waist" phenotype in men. Atherosclerosis 2003; 171(2):327-36.
Bossé Y, Vohl MC, Després JP, Lamarche B, Rice T, Rao DC, Bouchard C, Pérusse L. Heritability of LDL peak particle diameter in the Quebec Family Study.. Genet Epidemiol 2003; 25(4):375-81.
Blackburn P, Lamarche B, Couillard C, Pascot A, Tremblay A, Bergeron J, Lemieux I, Després JP. Contribution of visceral adiposity to the exaggerated postprandial lipemia of men with impaired glucose tolerance. Diabetes Care 2003; 26(12):3303-9.
Blackburn P, Côté M, Lamarche B, Couillard C, Pascot A, Tremblay A, Bergeron J, Lemieux I, Després JP. Impact of postprandial variation in triglyceridemia on low-density lipoprotein particle size. Metabolism 2003; 52(11):1379-86.
Poirier P, Després JP. [Obesity and cardiovascular disease]. Med Sci (Paris) 2003; 19(10):943-9.
Lemieux I, Salomon H, Després JP. Contribution of apo CIII reduction to the greater effect of 12-week micronized fenofibrate than atorvastatin therapy on triglyceride levels and LDL size in dyslipidemic patients.. Ann Med 2003; 35(6):442-8.
Archer WR, Lamarche B, St-Pierre AC, Mauger JF, Dériaz O, Landry N, Corneau L, Després JP, Bergeron J, Couture P, Bergeron N. High carbohydrate and high monounsaturated fatty acid diets similarly affect LDL electrophoretic characteristics in men who are losing weight.. J Nutr 2003; 133(10):3124-9.
Després JP. Potential contribution of metformin to the management of cardiovascular disease risk in patients with abdominal obesity, the metabolic syndrome and type 2 diabetes.. Diabetes Metab 2003; 29(4):6S53-61.
Archer WR, Lamarche B, Dériaz O, Landry N, Corneau L, Després JP, Bergeron J, Couture P, Bergeron N. Variations in body composition and plasma lipids in response to a high-carbohydrate diet.. Obes Res 2003; 11(8):978-86.
Scarsella C, Després JP. [Treatment of obesity: the need to target attention on high-risk patients characterized by abdominal obesity]. Cad Saude Publica 2003; 19(0):S7-19.
Paradis ME, Couture P, Bosse Y, Després JP, Pérusse L, Bouchard C, Vohl MC, Lamarche B. The T111I mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women.. J Lipid Res 2003; 44(10):1902-8.
Bossé Y, Després JP, Bouchard C, Pérusse L, Vohl MC. The peroxisome proliferator-activated receptor alpha L162V mutation is associated with reduced adiposity.. Obes Res 2003; 11(7):809-16.
Berthier MT, Houde A, Bergeron J, Prud'homme D, Després JP, Vohl MC. Effect of the factor VII R353Q missense mutation on plasma apolipoprotein B levels: impact of visceral obesity.. J Hum Genet 2003; 48(7):367-73.
Tremblay A, Bouchard L, Bouchard C, Després JP, Drapeau V, Pérusse L. Long-term adiposity changes are related to a glucocorticoid receptor polymorphism in young females.. J Clin Endocrinol Metab 2003; 88(7):3141-5.
Drapeau V, Provencher V, Lemieux S, Després JP, Bouchard C, Tremblay A. Do 6-y changes in eating behaviors predict changes in body weight? Results from the Québec Family Study. Int J Obes Relat Metab Disord 2003; 27(7):808-14.
Katzmarzyk PT, Tremblay A, Pérusse L, Després JP, Bouchard C. The utility of the international child and adolescent overweight guidelines for predicting coronary heart disease risk factors.. J Clin Epidemiol 2003; 56(5):456-62.
Provencher V, Drapeau V, Tremblay A, Després JP, Lemieux S. Eating behaviors and indexes of body composition in men and women from the Québec family study. Obes Res 2003; 11(6):783-92.
Hajamor S, Després JP, Couillard C, Lemieux S, Tremblay A, Prud'homme D, Tchernof A. Relationship between sex hormone-binding globulin levels and features of the metabolic syndrome. Metabolism 2003; 52(6):724-30.
Jacqmain M, Doucet E, Després JP, Bouchard C, Tremblay A. Calcium intake, body composition, and lipoprotein-lipid concentrations in adults. Am J Clin Nutr 2003; 77(6):1448-52.
Poirier P, Després JP. Waist circumference, visceral obesity, and cardiovascular risk.. J Cardiopulm Rehabil 2003; 23(3):161-9.
Bossé Y, Pérusse L, Després JP, Lamarche B, Chagnon YC, Rice T, Rao DC, Bouchard C, Vohl MC. Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter.. Circulation 2003; 107(18):2361-8.
Robitaille J, Després JP, Pérusse L, Vohl MC. The PPAR-gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: results from the Québec Family Study.. Clin Genet 2003; 63(2):109-16.
Berthier MT, Paradis AM, Tchernof A, Bergeron J, Prud'homme D, Després JP, Vohl MC. The interleukin 6-174G/C polymorphism is associated with indices of obesity in men.. J Hum Genet 2003; 48(1):14-9.
St-Pierre J, Miller-Felix I, Paradis ME, Bergeron J, Lamarche B, Després JP, Gaudet D, Vohl MC. Visceral obesity attenuates the effect of the hepatic lipase -514C>T polymorphism on plasma HDL-cholesterol levels in French-Canadian men.. Mol Genet Metab 2003; 78(1):31-6.
Imbeault P, Prins JB, Stolic M, Russell AW, O'Moore-Sullivan T, Després JP, Bouchard C, Tremblay A. Aging per se does not influence glucose homeostasis: in vivo and in vitro evidence. Diabetes Care 2003; 26(2):480-4.
Weltman A, Després JP, Clasey JL, Weltman JY, Wideman L, Kanaley J, Patrie J, Bergeron J, Thorner MO, Bouchard C, Hartman ML. Impact of abdominal visceral fat, growth hormone, fitness, and insulin on lipids and lipoproteins in older adults.. Metabolism 2003; 52(1):73-80.
Tremblay A, Dumesnil JG, Després JP. Diet, satiety and obesity treatment.. Br J Nutr 2002; 88(2):213-214.
Després JP. Who's the right patient for fenofibrate therapy?. Am J Cardiovasc Drugs 2002; 2(2):133-134.
Sacks FM, Després JP, et al.. The role of high-density lipoprotein (HDL) cholesterol in the prevention and treatment of coronary heart disease: Expert group recommendations.. Am J Cardiol 2002; 90(2):139-143.
Bertiher MT, Paradis AM, Tchernof A, Bergeron J, Prud'homme D, Després JP, Vohl MC. Biophysical characteristics of a new mutation on the KCNQ1 potassium channel (L251P) causing long QT syndrome.. Can J Physiol Pharmacol 2003; 81(2):129-34.
Ardern CI, Katzmarzyk PT, Janssen I, Leon AS, Wilmore JH, Skinner JS, Rao DC, Després JP, Rankinen T, Bouchard C. Race and sex similarities in exercise-induced changes in blood lipids and fatness.. Med Sci Sports Exerc 2004; 36(9):1610-5.
Cianflone K, Zakarian R, Couillard C, Delplanque B, Després JP, Sniderman A. Fasting acylation-stimulating protein is predictive of postprandial triglyceride clearance.. J Lipid Res 2004; 45(1):124-31.
Berthier MT, Vohl MC, Couture P, Houde A, Paradis AM, Sammak A, Verner A, Després JP. The c.419-420insA in the MTP gene is associated with a betalipoprotienemia among French-Canadians.. Mol Genet Metab 2004; 81(0):140-3.
Hogue JC, Lamarche B, Gaudet D, Larivière M, Tremblay AJ, Bergeron J, Lemieux I, Després JP, Gagné C, Couture P. Relationship between cholesteryl ester transfer protein and LDL heterogeneity in familial hypercholesterolemia.. J Lipid Res 2004; 45(6):1077-83.
Lakka HM, Tremblay A, Després JP, Bouchard C. Effects of long-term negative energy balance with exercise on plasma lipid and lipoprotein levels in identical twins.. Atherosclerosis 2004; 172(1):127-33.
Leon AS, Togashi K, Rankinen T, Després JP, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Association of apolipoprotein E polymorphism with blood lipids and maximal oxygen uptake in the sedentary state and after exercise training in the HERITAGE family study.. Metabolism 2004; 53(1):108-16.
Stanforth PR, Jackson AS, Green JS, Gagnon J, Rankinen T, Després JP, Bouchard C, Leon AS, Rao DC, Skinner JS, Wilmore JH. Generalized abdominal visceral fat prediction models for black and white adults aged 17-65 y: the HERITAGE Family Study.. Int J Obes Relat Metab Disord 2004; 28(7):925-32.
Terán-García M, Després JP, Couillard C, Tremblay A, Bouchard C. Effects of long-term overfeeding on plasma lipoprotein levels in identical twins.. Atherosclerosis 2004; 173(2):277-83.
Tanaka S, Togashi K, Rankinen T, Pérusse L, Leon AS, Rao DC, Skinner JS, Wilmore JH, Després JP, Bouchard C. Sex differences in the relationships of abdominal fat to cardiovascular disease risk among normal-weight white subjects.. Int J Obes Relat Metab Disord 2004; 28(2):320-3.
González-Barranco J, Ríos-Torres JM, Castillo-Martínez L, López-Alvarenga JC, Aguilar-Salinas CA, Bouchard C, Després JP, Tremblay A. Effect of malnutrition during the first year of life on adult plasma insulin and glucose tolerance. Metabolism 2003; 52(8):1005-11.
Bossé Y, Weisnagel SJ, Bouchard C, Després JP, Pérusse L, Vohl MC. Combined effects of PPARgamma2 P12A and PPARalpha L162V polymorphisms on glucose and insulin homeostasis: the Québec Family Study.. J Hum Genet 2003; 48(12):614-21.
Alméras N, Després JP, Villeneuve J, Demers MF, Roy MA, Cadrin C, Mottard JP, Bouchard RH. Development of an atherogenic metabolic risk factor profile associated with the use of atypical antipsychotics.. J Clin Psychiatry 2004; 65(4):557-64.
Tremblay AJ, Després JP, Piché ME, Nadeau A, Bergeron J, Alméras N, Tremblay A, Lemieux S. Associations between the fatty acid content of triglyceride, visceral adipose tissue accumulation, and components of the insulin resistance syndrome.. Metabolism 2004; 53(3):310-7.
Drapeau V, Després JP, Bouchard C, Allard L, Fournier G, Leblanc C, Tremblay A. Modifications in food-group consumption are related to long-term body-weight changes.. Am J Clin Nutr 2004; 80(1):29-37.
Piché ME, Després JP, Pascot A, Nadeau A, Tremblay A, Weisnagel SJ, Bergeron J, Lemieux S. Impaired fasting glucose vs. glucose intolerance in pre-menopausal women: distinct metabolic entities and cardiovascular disease risk?. Diabet Med 2004; 21(7):730-7.
Provencher V, Drapeau V, Tremblay A, Després JP, Bouchard C, Lemieux S,. Eating behaviours, dietary profile and body composition according to dieting history in men and women of the Québec Family Study.. Br J Nutr 2004; 91(6):997-1004.
Piché ME, Després JP, Pascot A, Nadeau A, Tremblay A, Weisnagel SJ, Bergeron J, Lemieux S. Predictors of the development of impaired fasting glucose versus impaired glucose tolerance are partly different in men: a 6-year follow-up study.. Diabetologia 2004; 47(3):590-2.
Boulé NG, Tremblay A, Gonzalez-Barranco J, Aguilar-Salinas CA, Lopez-Alvarenga JC, Després JP, Bouchard C, Gomez-Perez FJ, Castillo-Martinez L, Rios-Torres JM. Insulin resistance and abdominal adiposity in young men with documented malnutrition during the first year of life. Int J Obes Relat Metab Disord 2003; 27(5):598-604.
Bossé Y, Chagnon YC, Després JP, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Genome-wide linkage scan reveals multiple susceptibility loci influencing lipid and lipoprotein levels in the Quebec Family Study.. J Lipid Res 2004; 45(3):419-26.
Berthier MT, Houde A, Paradis AM, Couture P, Gaudet D, Després JP, Vohl MC. Molecular screening of the microsomal triglyceride transfer protein: association between polymorphisms and both abdominal obesity and plasma apolipoprotein B concentration.. J Hum Genet 2004; 49(12):684-90.
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després JP. Effect of type 2 diabetes on various electrophoretic characteristics of low-density lipoprotein particles in women.. Diabetologia 2004; 47(12):2114-7.
Radeau T, Lebel M, Houde I, Larivière R, Mauriège P, Kingma I, Lachance JG, Noël R, Després JP, Bergeron J. Endothelin-1 levels and cardiovascular risk factors in renal transplant patients.. Clin Biochem 2004; 37(12):1072-8.
Robitaille J, Brouillette C, Houde A, Després JP, Tchernof A, Vohl MC. Molecular screening of the 11beta-HSD1 gene in men characterized by the metabolic syndrome.. Obes Res 2004; 12(10):1570-5.
Hanaire-Broutin H, Després JP, Dubois-Randé JL, Grimaldi A. Assessment of the management of type 2 diabetes.. Presse Med 2004; 33(16):1121-3.
Després JP. CRP and risk of coronary heart disease: can exercise training cool down the flames?. Arterioscler Thromb Vasc Biol 2004; 24(10):1743-5.
Després JP, Lemieux I, Robins SJ. Role of fibric acid derivatives in the management of risk factors for coronary heart disease.. Drugs 2004; 64(19):2177-98.
Piché ME, Arcand-Bossé JF, Després JP, Pérusse L, Lemieux S, Weisnagel SJ. What is a normal glucose value? Differences in indexes of plasma glucose homeostasis in subjects with normal fasting glucose.. Diabetes Care 2004; 27(10):2470-7.
Bossé Y, Chagnon YC, Després JP, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Compendium of genome-wide scans of lipid-related phenotypes: adding a new genome-wide search of apolipoprotein levels.. J Lipid Res 2004; 45(12):2174-84.
Côté M, Mauriège P, Bergeron J, Alméras N, Tremblay A, Lemieux I, Després JP. Adiponectinemia in visceral obesity: impact on glucose tolerance and plasma lipoprotein and lipid levels in men.. J Clin Endocrinol Metab 2005; 90(3):1434-9.
St-Pierre AC, Cantin B, Dagenais GR, Mauriège P, Bernard PM, Després JP, Lamarche B. Low-density lipoprotein subfractions and the long-term risk of ischemic heart disease in men: 13-year follow-up data from the Québec Cardiovascular Study.. Arterioscler Thromb Vasc Biol 2005; 25(3):553-9.
Feitosa MF, Borecki IB, Rankinen T, Rice T, Després JP, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Bouchard C, Province MA, Rao DC. Evidence of QTLs on chromosomes 1q42 and 8q24 for LDL-cholesterol and apoB levels in the HERITAGE family study.. J Lipid Res 2005; 46(2):281-6.
Berthier MT, Houde A, Côté M, Paradis AM, Mauriège P, Bergeron J, Gaudet D, Després JP, Vohl MC. Impact of adiponectin gene polymorphisms on plasma lipoprotein and adiponectin concentrations of viscerally obese men.. J Lipid Res 2005; 46(2):237-44.
Poirier P, Després JP. Obésité et maladies cardiovasculaires.. Médecine & Sciences 2004; 31(0):10-15.
Bossé Y, Weisnagel JS, Bouchard C, Després JP, Pérusse L, Vohl MC. Combined effects of PPARgamma2 P12A and PPARalpha L162V polymorphisms on glucose and insulin homeostasis: the Québec family study.. J Hum Genet 2004; 48(12):614-21.
Blackburn P, Lemieux I, St-Pierre J, Scarsella C, Bergeron J, Després JP. Une nouvelle définition: la "taille hypertriglycéridémiante".. Réseaux diabète 2004; 0(0):5-8.
Després JP. Managing CHD risk in type 2 diabetes: improving insulin resistance may be as important as glycemic control.. Endocrine news 2004; 29(5):13-14.
St-Pierre AC, Cantin B, Mauriège P, Bergeron J, Dagenais GR, Després JP, Lamarche B. Insulin resistance syndrome, body mass index and the risk of ischemic heart disease.. CMAJ 2005; 172(10):1301-5.
St-Pierre J, Vohl MC, Després JP, Gaudet D, Poirier P. Genetic aspects of diabetes and its cardiovascular complications: contribution of genetics to risk assessment and clinical management.. Can J Cardiol 2005; 21(2):199-209.
Poirier P, Lemieux I, Mauriège P, Dewailly E, Blanchet C, Bergeron J, Després JP. Impact of waist circumference on the relationship between blood pressure and insulin: the Quebec Health Survey.. Hypertension 2005; 45(3):363-7.
Feitosa MF, Rice T, Rankinen T, Province MA, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Després JP, Bouchard C, Rao DC, Borecki IB. Evidence of QTLs on chromosomes 13q and 14q for triglycerides before and after 20 weeks of exercise training: the HERITAGE Family Study.. Atherosclerosis 2005; 182(2):349-60.
Hogue JC, Lamarche B, Gaudet D, Tremblay AJ, Després JP, Gagné C, Couture P. Genotype of the mutant LDL receptor allele is associated with LDL particle size heterogeneity in familial hypercholesterolemia.. Atherosclerosis 2006; 184(1):163-70.
Després JP, Golay A, Sjöström L,. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia.. N Engl J Med 2005; 353(20):2121-34.
Provencher V, Pérusse L, Bouchard L, Drapeau V, Bouchard C, Rice T, Rao DC, Tremblay A, Després JP, Lemieux S. Familial resemblances in eating behaviors in men and women from the Quebec Family Study.. Obes Res 2005; 13(9):1624-9.
St-Pierre AC, Cantin B, Bergeron J, Pirro M, Dagenais GR, Després JP, Lamarche B. Inflammatory markers and long-term risk of ischemic heart disease in men A 13-year follow-up of the Quebec Cardiovascular Study.. Atherosclerosis 2005; 182(2):315-21.
Bossé Y, Feitosa MF, Després JP, Lamarche B, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Detection of a major gene effect for LDL peak particle diameter and association with apolipoprotein H gene haplotype.. Atherosclerosis 2005; 182(2):231-9.
Blouin K, Després JP, Couillard C, Tremblay A, Prud'homme D, Bouchard C, Tchernof A. Contribution of age and declining androgen levels to features of the metabolic syndrome in men.. Metabolism 2005; 54(8):1034-40.
Després JP. Our passive lifestyle, our toxic diet, and the atherogenic/diabetogenic metabolic syndrome: can we afford to be sedentary and unfit?. Circulation 2005; 112(4):453-5.
An P, Borecki IB, Rankinen T, Després JP, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Evidence of major genes for plasma HDL, LDL cholesterol and triglyceride levels at baseline and in response to 20 weeks of endurance training: the HERITAGE Family Study.. Int J Sports Med 2005; 26(6):414-9.
Teran-Garcia M, Santoro N, Rankinen T, Bergeron J, Rice T, Leon AS, Rao DC, Skinner JS, Bergman RN, Després JP, Bouchard C. Hepatic lipase gene variant -514C>T is associated with lipoprotein and insulin sensitivity response to regular exercise: the HERITAGE Family Study.. Diabetes 2005; 54(7):2251-5.
Sénéchal M, Lemieux I, Beucler I, Drobinski G, Cormont S, Dubois M, Gandjbakhch I, Després JP, Dorent R. Features of the metabolic syndrome of "hypertriglyceridemic waist" and transplant coronary artery disease.. J Heart Lung Transplant 2005; 24(7):819-26.
Bossé Y, Bouchard L, Després JP, Bouchard C, Pérusse L, Vohl MC. Haplotypes in the phospholipid transfer protein gene are associated with obesity-related phenotypes: the Québec Family Study.. Int J Obes (Lond) 2005; 29(11):1338-45.
Eisenmann JC, Katzmarzyk PT, Perusse L, Tremblay A, Després JP, Bouchard C. Aerobic fitness, body mass index, and CVD risk factors among adolescents: the Québec family study.. Int J Obes (Lond) 2005; 29(9):1077-83.
Danesh J, Lewington S, Thompson SG, Lowe GD, Collins R, Kostis JB, Wilson AC, Folsom AR, Wu K, Benderly M, Goldbourt U, Willeit J, Kiechl S, Yarnell JW, Sweetnam PM, Elwood PC, Cushman M, Psaty BM, Tracy RP, Tybjaerg-Hansen A, Haverkate F, de Maat MP, Fow. Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality. An individual participant meta-analysis. JAMA 2005; 294(22):1799-1809.
St-Pierre AC, Cantin B, Dagenais GR, Després JP, Lamarche B. Apolipoprotein-B, low-density lipoprotein cholesterol, and the long-term risk of coronary heart disease in men.. Am J Cardiol 2006; 97(7):997-1001.
Teran-Garcia M, Després JP, Tremblay A, Bouchard C. Effects of cholesterol ester transfer protein (CETP) gene on adiposity in response to long-term overfeeding.. Atherosclerosis 2006; 0(0):Epub.
Poirier P, Després JP. [Impact of obesity in contemporary cardiology]. Med Sci (Paris) 2005; 21(0):3-9.
St-Pierre AC, Cantin B, Dagenais GR, Després JP, Lamarche B. The relationship between dysglycemia, cardiovascular and renal risk in diabetic and nondiabetic participants in the HOPE study: A prospective epidemiologic analysis.. Diabetologia 2005; 48(0):1749-55.
Després JP. Is visceral obesity the cause of the metabolic syndrome?. Ann Med 2006; 38(1):52-63.
Després JP, Lamarche B, Mauriège P, Cantin B, Dagenais GR, Moorjani S, Lupien PJ. Hyperinsulinemia as an independent risk factor for ischemic heart disease.. N Engl J Med 1996; 334(15):952-7.
Després JP, Lemieux I, Prud'homme D. Treatment of obesity: need to focus on high risk abdominally obese patients.. BMJ 2001; 322(7288):716-20.
Despres JP, Moorjani S, Lupien PJ, Tremblay A, Nadeau A, Bouchard C. Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease.. Arteriosclerosis 1990; 10(4):497-511.
Bossé Y, Després JP, Chagnon YC, Rice T, Rao DC, Bouchard C, Pérusse L, Vohl MC. Quantitative trait locus on 15q for a metabolic syndrome variable derived from factor analysis.. Obesity (Silver Spring) 2007; 15(3):544-50.
Chaput JP, Després JP, Bouchard C, Tremblay A. Short sleep duration is associated with reduced leptin levels and increased adiposity: Results from the Quebec Family Study.. Obesity (Silver Spring) 2007; 15(1):253-61.
Briand M, Pibarot P, Després JP, Voisine P, Dumesnil JG, Dagenais F, Mathieu P. Metabolic syndrome is associated with faster degeneration of bioprosthetic valves.. Circulation 2006; 141(1):I512-7.
Després JP, Lemieux I, Alméras N. Contribution of CB1 blockade to the management of high-risk abdominal obesity.. Int J Obes (Lond) 2006; 30(0):S44-52.
Poirier P, Després JP, Bertrand OF. Identifying which patients with diabetes should be tested for the presence of coronary artery disease - The importance of baseline electrocardiogram and exercise testing.. Can J Cardiol 2006; 22(0):9-15.
Briand M, Lemieux I, Dumesnil JG, Mathieu P, Cartier A, Després JP, Arsenault M, Couet J, Pibarot P. Metabolic syndrome negatively influences disease progression and prognosis in aortic stenosis.. J Am Coll Cardiol 2006; 47(11):2229-36.
Mathieu P, Pibarot P, Després JP. Metabolic syndrome: The danger signal in atherosclerosis.. Vasc Health Risk Manag 2006; 2(3):285-302.
Després JP, Lemieux I. Abdominal obesity and metabolic syndrome.. Nature 2006; 444(7121):881-7.
Blackburn P, Després JP, Lamarche B, Tremblay A, Bergeron J, Lemieux I, Couillard C. Postprandial variations of plasma inflammatory markers in abdominally obese men.. Obesity (Silver Spring) 2006; 14(10):1747-54.
Scheen AJ, Van Gaal LG, Després JP, Pi-Sunyer X, Golay A, Hanotin C. Rimonabant improves cardiometabolic risk profile in obese or overweight subjects: overview of RIO studies. Rev Med Suisse 2006; 2(76):1916-23.
Désilets MC, Garrel D, Couillard C, Tremblay A, Després JP, Bouchard C, Delisle H. Ethnic differences in body composition and other markers of cardiovascular disease risk: study in matched Haitian and White subjects from Quebec.. Obesity (Silver Spring) 2006; 14(6):1019-27.
Després JP. Intra-abdominal obesity: an untreated risk factor for Type 2 diabetes and cardiovascular disease.. J Endocrinol Invest 2006; 29(3):77-82.
Echahidi N, Pibarot P, Després JP, Daigle JM, Mohty D, Voisine P, Baillot R, Mathieu P. Metabolic syndrome increases operative mortality in patients undergoing coronary artery bypass grafting surgery.. J Am Coll Cardiol 2007; 50(9):843-51.
Tremblay A, Chaput JP, Bérubé-Parent S, Prud'homme D, Leblanc C, Alméras N, Després JP. The effect of topiramate on energy balance in obese men: a 6-month double-blind randomized placebo-controlled study with a 6-month open-label extension.. Eur J Clin Pharmacol 2007; 63(2):123-34.
Hogue JC, Lamarche B, Gaudet D, Tremblay AJ, Després JP, Bergeron J, Gagné C, Couture P. Association of heterozygous familial hypercholesterolemia with smaller HDL particle size.. Atherosclerosis 2007; 190(2):429-35.
St-Pierre J, Lemieux I, Perron P, Brisson D, Santuré M, Vohl MC, Després JP, Gaudet D. Relation of the "hypertriglyceridemic waist" phenotype to earlier manifestations of coronary artery disease in patients with glucose intolerance and type 2 diabetes mellitus.. Am J Cardiol 2007; 99(3):369-73.
Després JP. Abdominal obesity: the most prevalent cause of the metabolic syndrome and related cardiometabolic risk.. Eur Heart J 2006; 0(0):B4-12.
Després JP. How effective is rimonabant at promoting and maintaining weight loss in patients with obesity? (Commentary). Nat Clin Pract Endocrinol Metab 2006; 2(8):428-9.
Arsenault BJ, Lachance D, Lemieux I, Alméras N, Tremblay A, Bouchard C, Pérusse L, Després JP. Visceral adipose tissue accumulation, cardiorespiratory fitness, and features of the metabolic syndrome.. Arch Intern Med 2007; 167(14):1518-25.
Côté M, Matias I, Lemieux I, Petrosino S, Alméras N, Després JP, DiMarzo V. Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men.. Int J Obes 2007; 31(4):692-9.
Echahidi N, Mohty D, Pibarot P, Després JP, O'Hara G, Champagne J, Philippon F, Daleau P, Voisine P, Mathieu P. Obesity and metabolic syndrome are independent risk factors for atrial fibrillation after coronary artery bypass graft surgery.. Circulation 2007; 116(11):I213-9.
Dagenais GR, Philippon F, Després JP, Dumesnil JG, Cartier P, Bogaty P, Lemieux M, Moisan A. The Quebec Heart Institute : 50 years of excellence in cardiology.. Can J Cardiol 2007; 23(0):5-8B.
Després JP, Smith JE, Chilvers LD. How many of our patients are military? A study of Emergency Department attendance at Derriford Hospital, March to August 2006.. J R Nav Med Serv 2007; 93(3):129-31.
Loos RJ, Rankinen T, Pérusse L, Tremblay A, Després JP, Bouchard C. Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism.. Obesity (Silver Spring) 2007; 15(11):2723-32.
Balkau B, Deanfield JE, Després JP, Bassand JP, Fox KA, Smith SC, Barter P, Tan CE, Van Gaal L, Wittchen HU, Massien C, Haffner SM. International Day for the Evaluation of Abdominal Obesity (IDEA): a study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countries.. Circulation 2007; 116(17):1942-51.
Ross R, Berentzen T, Bradshaw AJ, Janssen I, Kahn HS, Katzmarzyk PT, Kuk JL, Seidell JC, Snijder MB, Sørensen TI, Després JP. Does the relationship between waist circumference, morbidity and mortality depend on measurement protocol for waist circumference?. Obes Rev 2008; 9(4):312-25.
Arsenault BJ, Lemieux I, Després JP, Wareham NJ, Luben R, Kastelein JJ, Khaw KT, Boekholdt SM. Cholesterol levels in small LDL particles predict the risk of coronary heart disease in the EPIC-Norfolk prospective population study.. Eur Heart J 2007; 28(22):2770-7.
Côté C, Pibarot P, Despres JP, Mohty D, Cartier A, Arsenault B, Couture C, Mathieu P. Association between circulating oxidized low-density lipoprotein and fibro-calcific remodeling of the aortic valve in aortic stenosis.. Heart 2007; 0(0):Epub.
Perron P, Brisson D, Santuré M, Blackburn P, Bergeron J, Vohl MC, Després JP, Gaudet D. Apolipoprotein E and lipoprotein lipase gene polymorphisms interaction on the atherogenic combined expression of hypertriglyceridemia and hyperapobetalipoproteinemia phenotypes.. J Endocrinol Invest 2007; 30(7):551-7.
Chaput JP, Després JP, Bouchard C, Tremblay A. Association of sleep duration with type 2 diabetes and impaired glucose tolerance.. Diabetologia 2007; 50(11):2298-304.
Després JP. Cardiovascular disease under the influence of excess visceral fat.. Crit Pathw Cardiol 2007; 6(2):51-9.
Després JP. The endocannabinoid system: a new target for the regulation of energy balance and metabolism.. Crit Pathw Cardiol 2007; 6(2):46-50.
Brisson D, St-Pierre J, Santuré M, Hudson TJ, Després JP, Vohl MC, Gaudet D. Genetic epistasis in the VLDL catabolic pathway is associated with deleterious variations on triglyceridemia in obese subjects.. Int J Obes 2007; 31(8):1325-33.
Dolley G, Berthier MT, Lamarche B, Després JP, Bouchard C, Pérusse L, Vohl MC. Influences of the phosphatidylcholine transfer protein gene variants on the LDL peak particle size.. Atherosclerosis 2007; 195(2):297-302.
Lemieux I, Poirier P, Bergeron J, Almeras N, Lamarche B, Cantin B, Dagenais GR, Després JP. Hypertriglyceridemic waist: A useful screeing phenotype in preventive cardiology?. Can J Cardiol 2007; 23(0):23-31B.
Mathieu P, Després JP, Pibarot P. The "valvulo-metabolic" risk in calcific aortic valve disease.. Can J Cardiol 2007; 23(0):32-9B.
Terán-García M, Després JP, Tremblay A, Bouchard C. Effects of cholesterol ester transfer protein (CETP) gene on adiposity in response to long-term overfeeding.. Atherosclerosis 2008; 196(1):455-60.
Bouhali T, Brisson D, St-Pierre J, Tremblay G, Perron P, Laprise C, Vohl MC, Vissers MN, Hutten BA, Després JP, Kastelein JJ, Gaudet D. Low plasma adiponectin exacerbates the risk of premature coronary artery disease in familial hypercholesterolemia.. Atherosclerosis 2008; 196(1):262-9.
Dolley G, Lamarche B, Després JP, Bouchard C, Pérusse L, Vohl MC. Myeloperoxidase gene sequence variations are associated with low-density-lipoprotein characteristics.. J Hum Genet 2008; 0(0):Epub.
Ruchat SM, Loos RJ, Rankinen T, Vohl MC, Weisnagel SJ, Després JP, Bouchard C, Pérusse L. Associations between glucose tolerance, insulin sensitivity and insulin secretion phenotypes and polymorphisms in adiponectin and adiponectin receptor genes in the Quebec Family Study.. Diabet Med 2008; 25(4):400-6.
Després JP, Van Gaal L, Pi-Sunyer X, Scheen A. Efficacy and safety of the weight-loss drug rimonabant.. Lancet 2008; 371(9612):555.
Van Gaal L, Pi-Sunyer X, Després JP, McCarthy C, Scheen A. Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program.. Diabetes Care 2008; 31(0):S229-40.
Mathieu P, Pibarot P, Larose E, Poirier P, Marette A, Després JP. Visceral obesity and the heart.. Int J Biochem Cell Biol 2008; 40(5):821-36.
Ruilope LM, Després JP, Scheen A, Pi-Sunyer X, Mancia G, Zanchetti A, Van Gaal L. Effect of rimonabant on blood pressure in overweight/obese patients with/without co-morbidities: analysis of pooled RIO study results.. J Hypertens 2008; 26(2):357-67.
Mohty D, Pibarot P, Després JP, Côté C, Arsenault B, Cartier A, Cosnay P, Couture C, Mathieu P. Association between plasma LDL particle size, valvular accumulation of oxidized LDL, and inflammation in patients with aortic stenosis.. Arterioscler Thromb Vasc Biol 2008; 28(1):187-93.
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després JP. Type 2 diabetes without the atherogenic metabolic triad does not predict angiographically assessed coronary artery disease in women.. Diabetes Care 2008; 31(1):170-2.
Mertens I, Lemieux I, Verrijken A, Després JP, Van Gaal LF. PAI-1 activity, but not fibrinogen or von Willebrand factor, is inversely related to LDL particle size in type 2 diabetes.. Diabetes Metab Res Rev 2008; 24(2):141-7.
Boulé NG, Chaput JP, Doucet E, Richard D, Després JP, Bouchard C, Tremblay A. Glucose homeostasis predicts weight gain: prospective and clinical evidence.. Diabetes Metab Res Rev 2008; 24(2):123-9.
Loos RJF, Rankinen T, Pérusse L, Tremblay A, Després JP, Bouchard C. Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism.. Obesity Silver Spring 2007; 15(11):2723-32.
Després JP, Lemieux I, Bergeron J, Pibarot P, Mathieu P, Larose E, Rodés-Cabau J, Bertrand OF, Poirier P. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk.. Arterioscler Thromb Vasc Biol 2008; 28(6):1039-49.
Després JP, Pérusse L. Genetic and nutritional determinants of the metabolic syndrome: introduction.. J Nutrigenet Nutrigenomics 2008; 1(0):97-9.
Després JP, Poirier P, Bergeron J, Tremblay A, Lemieux I, Alméras N. From individual risk factors and the metabolic syndrome to global cardiometabolic risk.. Eur Heart J Suppl 2008; 10(0):B24-33.
Després JP, Brewer HB. Metabolic syndrome: the dysmetabolic state of dysfunctional adipose tissue and insulin resistance.. Eur Heart J Suppl 2008; 10(0):B1-3.
Lau DCW, Douketis JD, Morrison KM, Hramiak IM, Sharma AM, Ur E, for membres of the Obesity Canada Clinical Practice Guidelines Expert Panel (Després JP, expert panel member). 2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children (summary).. CMAJ 2007; 176(8):S1-13.
Després JP, Prud'homme D, Lemieux I. Treatment of obesity: need to focus on high risk abdominally obese patients.. BMJ 2001; 322(0):716-20.
Després JP. Visceral adipose tissue and its contribution to global cardiometabolic risk.. BCM Baylor College of Medicine Reports on Cardiometabolic Disorders 2007; 1(3):1-11.
Fibrinogen Studies Collaboration (see end of article: Després JP).. Associations of plasma fibrinogen levels with established cardiovascular risk factors, inflammatory markers and other characteristics: individual participant meta-analysis of 154,211 adults in 31 pros. Am J Epidemiol 2007; 166(8):867-79.
Cartier A, Côté M, Lemieux I, Després JP. Inflammation, résistance à linsuline et obésité. Les actualités du cur 2007; 10(3):8-9.
Chaput JP, Pelletier C, Després JP, Lemieux S, Tremblay A. Metabolic and behavioral vulnerability related to weight regain in reduced-obese men might be prevented by an adequate diet-exercise intervention.. Appetite 2007; 49(3):691-5.
Després JP, Ross R, Boka G, Alméras N, Lemieux I, . Effect of rimonabant on the high-triglyceride/ low-HDL-cholesterol dyslipidemia, intraabdominal adiposity, and liver fat: the ADAGIO-Lipids trial.. Arterioscler Thromb Vasc Biol 2009; 29(3):416-23.
Arsenault BJ, Lemieux I, Després JP, Wareham NJ, Stroes ES, Kastelein JJ, Khaw KT, Boekholdt SM. Comparison between Gradient Gel Electrophoresis and Nuclear Magnetic Resonance Spectroscopy in Estimating Coronary Heart Disease Risk Associated with LDL and HDL Particle Size.. Clin Chem 2010; 56(5):789-98.
The Emerging Risk Factors Collaboration; Investigators/Contributors; Québec Cardiovascular Study: Cantin B, Lamarche B, Després JP, Dagenais GR. Major lipids, apolipoproteins, and risk of vascular disease.. JAMA 2009; 302(18):1993-2000.
Nissen SE, Nicholls SJ, Wolski K, Rodés-Cabau J, Cannon CP, Deanfield JE, Després JP, Kastelein JJ, Steinhubl SR, Kapadia S, Yasin M, Ruzyllo W, Gaudin C, Job B, Hu B, Bhatt DL, Lincoff AM, Tuzcu EM. Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial.. JAMA 2008; 299(13):1547-60.
Ukkola O, Terán-García M, Tremblay A, Després JP, Bouchard C. Adiponectin concentration and insulin indicators following overfeeding in identical twins.. J Endocrinol Invest 2008; 31(2):132-7.
Després JP. CVD risk assessment: do we need the metabolic syndrome or better global cardiometabolic risk calculators?. Int J Obes 2008; 32(0):S1-4.
Cartier A, Lemieux I, Alméras N, Tremblay A, Bergeron J, Després JP. Visceral obesity and plasma glucose-insulin homeostasis: contributions of interleukin-6 and tumor necrosis factor-alpha in men.. J Clin Endocrinol Metab 2008; 93(5):1931-8.
Chaput JP, Després JP, Bouchard C, Tremblay A. The association between sleep duration and weight gain in adults: a 6-year prospective study from the Quebec Family Study.. Sleep 2008; 31(4):517-23.
Ruchat SM, Després JP, Weisnagel SJ, Chagnon YC, Bouchard C, Pérusse L. Genome-wide linkage analysis for circulating levels of adipokines and C-reactive protein in the Quebec family study (QFS).. J Hum Genet 2008; 53(7):629-36.
Côté C, Pibarot P, Després JP, Mohty D, Cartier A, Arsenault BJ, Couture C, Mathieu P. Association between circulating oxidised low-density lipoprotein and fibrocalcific remodelling of the aortic valve in aortic stenosis.. Heart 2008; 94(9):1175-80.
Després JP, Arsenault BJ, Côté M, Cartier A, Lemieux I. Abdominal obesity: the cholesterol of the 21st century?. Can J Cardiol 2008; 24(0):7D-12D.
Després JP, Cartier A, Côté M, Arsenault BJ. The concept of cardiometabolic risk: bridging the fields of diabetology and cardiology.. Ann Med 2008; 40(7):514-23.
Wolf AM, Finer N, Allshouse AA, Pendergast KB, Sherrill BH, Caterson I, Hill JO, Aronne LJ, Hauner H, Radigue C, Amand C, Despres JP. PROCEED: Prospective Obesity Cohort of Economic Evaluation and Determinants: baseline health and healthcare utilization of the US sample.. Diabetes Obes Metab 2008; 10(12):1248-60.
Desprès JP, Arsenault BJ, Poirier P. Management of the atherogenic dyslipidemia of insulin resistance/metabolic syndrome: making visceral obesity/ectopic fat a new therapeutic target.. Med Clin North Am 2008; 92(1):11-26.
Dagenais GR, St-Pierre A, Gilbert P, Lamarche B, Després JP, Bernard PM, Bogaty P. Comparison of prognosis for men with type 2 diabetes mellitus and men with cardiovascular disease.. CMAJ 2009; 180(1):40-7.
Arsenault BJ, Pibarot P, Després JP. The quest for optimal assessment of global cardiovascular risk: are tradional risk factors and metabolic syndrome partners in crime?. Cardiol 2009; 113(0):35-49.
Harchaoui KE, Arsenault BJ, Franssen R, Després JP, Hovingh K, Stroes ESG, Otvos JD, Wareham NJ, Kastelein JJP, Khaw KT, Boekholdt SM. HDL size and HDL particle concentration independently predict coronary artery disease risk in apparently healthy individuals. The EPIC-Norfolk prospective population study.. Ann Intern Med 2009; 150(0):84-93.
Després JP. Pleiotropic effects of rimonabant: clinical implications.. Curr Pharm Des 2009; 15(5):553-570.
Côté N, Pibarot P, Pépin A, Fournier D, Audet A, Arsenault B, Couture C, Poirier P, Després JP, Mathieu P. Oxidized low-density lipoprotein, angiotensin II and increased waist circumference are associated with valve inflammation in prehypertensive patients with aortic stenosis.. J Cardiol 2009; 0(0):Epub (12 juin).
Arsenault BJ, Lemieux I, Després JP, Gagnon P, Wareham NJ, Stroes ESG, Kastelein JJP, Khaw KT, Boekholdt SM. HDL particle size and the risk of coronary heart disease in apparently healthy men and women: The EPIC-Norfolk Prospective Population Study.. Atherosclerosis 2009; 206(1):276-81.
Chaput JP, Després JP, Bouchard C, Astrup A, Tremblay A. Sleep duration as a risk factor for the development of type 2 diabetes or impaired glucose tolerance: analyses of the Quebec Family Study.. Sleep Med 2009; 10(8):919-24.
Girerd N, Pibarot P, Fournier D, Daleau P, Voisine P, O'Hara G, Després JP, Mathieu P. Middle-aged men with increased waist circumference and elevated C-reactive protein level are at higher risk for postoperative atrial fibrillation following coronary artery bypass grafting surgery.. Eur Heart J 2009; 30(10):1270-8.
Cartier A, Côté M, Lemieux I, Pérusse L, Tremblay A, Bouchard C, Després JP. Sex differences in inflammatory markers: what is the contribution of visceral adiposity?. Am J Clin Nutr 2009; 89(0):1307-14.
Malik VS, Popkin BM, Bray GA, Després JP, Hu FB. Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk.. Circulation 2010; 121(11):1356-64.
Chaput JP, Leblanc C, Pérusse L, Després JP, Bouchard C, Tremblay A. Risk Factors for Adult Overweight and Obesity in the Quebec Family Study: Have We Been Barking Up the Wrong Tree?. Obesity (Silver Spring) 2009; 17(10):1964-70.
Mohty D, Pibarot P, Després JP, Cartier A, Arsenault B, Picard F, Mathieu P. Age-related differences in the pathogenesis of calcific aortic stenosis: the potential role of resistin.. Int J Cardiol 2009; 0(0):Epub (20 janv.).
Cartier A, Bergeron J, Poirier P, Alméras N, Tremblay A, Lemieux I, Després JP. Increased plasma interleukin-1 receptor antagonist levels in men with visceral obesity.. Ann Med 2009; 41(6):471-8.
Després JP. Bringing JUPITER down to earth.. Lancet 2009; 373(9670):1147-8.
Mathieu P, Lemieux I, Després JP. Obesity, inflammation, and cardiovascular risk.. Clin Pharmacol Ther 2010; 87(4):407-16.
Cartier A, Côté M, Bergeron J, Alméras N, Tremblay A, Lemieux I, Després JP. Plasma soluble tumour necrosis factor-alpha receptor 2 is elevated in obesity: specific contribution of visceral adiposity.. Clin Endocrinol (Oxf) 2010; 72(3):349-57.
Rana JS, Visser ME, Arsenault BJ, Després JP, Stroes ESG, Kastelein JJP, Wareham NJ, Khaw KT, Boekholdt SM. Metabolic dyslipidemia and risk of future coronary heart disease in healthy men and women: the EPIC-Norfolk Prospective Population Study.. Int J Cardiol 2009; 0(0):Epub.
Després JP. The expert weighs in. Pharmacology for the treatment of obesity: is there a place for rimonabant?. Obes Manag 2008; 4(2):51-55.
Després JP, Arsenault BJ. L'obésité abdominale: un facteur de risque sous-évalué en prévention du dibète de type 2 et des maladies cardiovasculaires.. Plein Soleil, Revue de diabète Québec 2008; 0(0):22-25.
Després JP, Poirier P. Obesity at risk vs. adiposity at risk: is there a difference?. BMJ 2008; 0(0):epub.
Mathieu P, Poirier P, Pibarot P, Lemieux I, Després JP. Visceral obesity: the link among inflammation, hypertension, and cardiovascular disease.. Hypertension 2009; 53(4):577-84.
Derbali H, Bossé Y, Pibarot P, Audet A, Pépin A, Arsenault B, Couture C, Després JP, Mathieu P. Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via Toll-like receptor 2.. Am J Pathol 2010; 176(6):2638-45.
The Emerging Risk Factors Collaboration; Investigators/Contributors; Québec Cardiovascular Study: Cantin B, Lamarche B, Després JP, Dagenais GR.. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke and nonvascular mortality.. JAMA 2009; 302(4):412-23.
Dolley G, Lamarche B, Després JP, Bouchard C, Pérusse L, Vohl MC. Phosphoinositide cycle gene polymorphisms affect the plasma lipid profile in the Quebec Family Study.. Mol Genet Metab 2009; 97(2):149-54.
Pendergast K, Wolf A, Sherrill B, Zhou X, Aronne LJ, Caterson I, Finer N, Hauner H, Hill J, Van Gaal L, Coste F, Despres JP. Impact of Waist Circumference Difference on Health-Care Cost among Overweight and Obese Subjects: The PROCEED Cohort.. Value Health 2010; 13(4):402-10.
Arsenault BJ, Rana JS, Lemieux I, Després JP, Kastelein JJ, Boekholdt SM, Wareham NJ, Khaw KT. Physical inactivity, abdominal obesity and risk of coronary heart disease in apparently healthy men and women.. Int J Obes (Lond) 2010; 34(2):340-7.
Arsenault BJ, Rana JS, Lemieux I, Després JP, Wareham NJ, Kastelein JJ, Boekholdt SM, Khaw KT. Physical activity, the Framingham risk score and risk of coronary heart disease in men and women of the EPIC-Norfolk study.. Atherosclerosis 2010; 209(1):261-5.
Rhéaume C, Arsenault BJ, Bélanger S, Pérusse L, Tremblay A, Bouchard C, Poirier P, Després JP. Low Cardiorespiratory Fitness Levels and Elevated Blood Pressure: What Is the Contribution of Visceral Adiposity?. Hypertension 2009; 54(1):91-7.
Blackburn P, Lemieux I, Alméras N, Bergeron J, Côté M, Tremblay A, Lamarche B, Després JP. The hypertriglyceridemic waist phenotype versus the National Cholesterol Education Program-Adult Treatment Panel III and International Diabetes Federation clinical criteria to identify high-risk men with an altered cardiometabolic risk profile.. Metabolism 2009; 58(8):1123-30.
Blouin M, Binet M, Bouchard RH, Roy MA, Després JP, Alméras N. Improvement of metabolic risk profile under second-generation antipsychotics: a pilot intervention study.. Can J Psychiatry 2009; 54(4):275-9.
Di Marzo V, Côté M, Matias I, Lemieux I, Arsenault BJ, Cartier A, Piscitelli F, Petrosino S, Alméras N, Després JP. Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors.. Diabetologia 2009; 52(2):213-7.
Arsenault BJ, Côté M, Cartier A, Lemieux I, Després JP, Ross R, Earnest CP, Blair SN, Church TS. Effect of exercise training on cardiometabolic risk markers among sedentary, but metabolically healthy overweight or obese post-menopausal women with elevated blood pressure.. Atherosclerosis 2009; 207(2):530-3.
Després JP. Targeting abdominal obesity and the metabolic syndrome to manage cardiovascular disease risk.. Heart 2009; 95(13):1118-24.
Saunders TJ, Davidson LE, Janiszewski PM, Després JP, Hudson R, Ross R. Associations of the limb fat to trunk fat ratio with markers of cardiometabolic risk in elderly men and women.. J Gerontol A Biol Sci Med Sci 2009; 64(10):1066-70.
Arsenault BJ, Cartier A, Côté M, Lemieux I, Tremblay A, Bouchard C, Pérusse L, Després JP. Body composition, cardiorespiratory fitness, and low-grade inflammation in middle-aged men and women.. Am J Cardiol 2009; 104(2):240-6.
Rana JS, Cote M, Després JP, Sandhu MS, Talmud PJ, Ninio E, Wareham NJ, Kastelein JJ, Zwinderman AH, Khaw KT, Boekholdt SM. Inflammatory biomarkers and the prediction of coronary events among people at intermediate risk: the EPIC-Norfolk prospective population study.. Heart 2009; 95(20):1682-7.
Cartier A, Côté M, Lemieux I, Pérusse L, Tremblay A, Bouchard C, Després JP. Age-related differences in inflammatory markers in men: contribution of visceral adiposity.. Metabolism 2009; 58(10):1452-8.
Payette C, Blackburn P, Lamarche B, Tremblay A, Bergeron J, Lemieux I, Després JP, Couillard C. Sex differences in postprandial plasma tumor necrosis factor-alpha, interleukin-6, and C-reactive protein concentrations.. Metabolism 2009; 58(11):1593-601.
Arsenault BJ, Earnest CP, Després JP, Blair SN, Church TS. Obesity, coffee consumption and CRP levels in postmenopausal overweight/obese women: importance of hormone replacement therapy use.. Eur J Clin Nutr 2009; 63(12):1419-24.
Fox KA, Després JP, Richard AJ, Brette S, Deanfield JE, . Does abdominal obesity have a similar impact on cardiovascular disease and diabetes? A study of 91,246 ambulant patients in 27 European countries.. Eur Heart J 2009; 30(24):3055-63.
Di Marzo V, Després JP. CB1 antagonists for obesity--what lessons have we learned from rimonabant?. Nat Rev Endocrinol 2009; 5(11):633-8.
Ross R, Després JP. Abdominal obesity, insulin resistance, and the metabolic syndrome: contribution of physical activity/exercise.. Obesity (Silver Spring) 2009; 17(0):S1-2.
Arsenault BJ, Rana JS, Stroes ES, Després JP, Shah PK, Kastelein JJ, Wareham NJ, Boekholdt SM, Khaw KT. Beyond low-density lipoprotein cholesterol: respective contributions of non-high-density lipoprotein cholesterol levels, triglycerides, and the total cholesterol/high-density lipoprotein cholesterol ratio to coronary heart disease risk in apparently healthy men and women.. J Am Coll Cardiol 2009; 55(1):35-41.
Shetty R, Pibarot P, Audet A, Janvier R, Dagenais F, Perron J, Couture C, Voisine P, Després JP, Mathieu P. Lipid-mediated inflammation and degeneration of bioprosthetic heart valves.. Eur J Clin Invest 2009; 39(6):471-80.
, Jackson D, White I, Kostis JB, Wilson AC, Folsom AR, Wu K, Chambless L, Benderly M, Goldbourt U, Willeit J, Kiechl S, Yarnell JW, Sweetnam PM, Elwood PC, Cushman M, Psaty BM, Tracy RP, Tybjaerg-Hansen A, Haverkate F, de Maat MP, Thompson SG, Fowkes FG, Lee AJ, Smith FB, Salomaa V, Harald K, Rasi V, Vahtera E, Jousilahti P, D'Agostino R, Kannel WB, Wilson PW, Tofler G, Levy D, Marchioli R, Valagussa F, Rosengren A, Wilhelmsen L, Lappas G, Eriksson H, Cremer P, Nagel D, Curb JD, Rodriguez B, Yano K, Salonen JT, Nyyssönen K, Tuomainen TP, Hedblad B, Engström G, Berglund G, Loewel H, Koenig W, Hense HW, Meade TW, Cooper JA, De Stavola B, Knottenbelt C, Miller GJ, Cooper JA, Bauer KA, Rosenberg RD, Sato S, Kitamura A, Naito Y, Iso H, Salomaa V, Harald K, Rasi V, Vahtera E, Jousilahti P, Palosuo T, Ducimetiere P, Amouyel P, Arveiler D, Evans AE, Ferrieres J, Juhan-Vague I, Bingham A, Schulte H, Assmann G, Cantin B, Lamarche B, Despres JP, Dagenais GR, Tunstall-Pedoe H, Lowe GD, Woodward M, Ben-Shlomo Y, Davey Smith G, Palmieri V, Yeh JL, Meade TW, Rudnicka A, Brennan P, Knottenbelt C, Cooper JA, Ridker P, Rodeghiero F, Tosetto A, Shepherd J, Lowe GD, Ford I, Robertson M, Brunner E, Shipley M, Feskens EJ, Di Angelantonio E, Kaptoge S, Lewington S, Lowe GD, Sarwar N, Thompson SG, Walker M, Watson S, White IR, Wood AM, Danesh J. Systematically missing confounders in individual participant data meta-analysis of observational cohort studies.. Stat Med 2009; 28(8):1218-37.
Rodés-Cabau J, Bertrand OF, Larose E, Déry JP, Rinfret S, Bagur R, Proulx G, Nguyen CM, Côté M, Landcop MC, Boudreault JR, Rouleau J, Roy L, Gleeton O, Barbeau G, Noël B, Courtis J, Dagenais GR, Després JP, DeLarochellière R. Comparison of plaque sealing with paclitaxel-eluting stents versus medical therapy for the treatment of moderate nonsignificant saphenous vein graft lesions: the moderate vein graft lesion stenting with the taxus stent and intravascular ultrasound (VELETI) pilot trial.. Circulation 2009; 120(20):1978-86.
Bertrand OF, Poirier P, Rodés-Cabau J, Rinfret S, Title L, Dzavik V, Natarajan M, Angel J, Batalla N, Alméras N, Costerousse O, De Larochellière R, Roy L, Després JP, . A multicentre, randomized, double-blind placebo-controlled trial evaluating rosiglitazone for the prevention of atherosclerosis progression after coronary artery bypass graft surgery in patients with type 2 diabetes. Design and rationale of the VeIn-Coronary aTherOsclerosis and Rosiglitazone after bypass surgerY (VICTORY) trial.. Can J Cardiol 2009; 25(9):509-15.
The Fibrinogen Studies Collaboration; Authors/Collaborators and Study Members; Québec Cardiovascular Study: Cantin B, Lamarche B, Després JP, Dagenais GR.. Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies.. Stat Med 2009; 28(7):1067-92.
Rana JS, Arsenault BJ, Després JP, Côté M, Talmud PJ, Ninio E, Jukema W, Wareham NJ, Kastelein JJP, Khaw KT, Boekholdt SM. Inflammatory biomarkers, physical activity, waist circumference and risk of future heart disease in healthy men and women.. Eur Heart J 2009; 0(0):Epub.
The Fibrinogen Studies Collaboration; Authors/Collaborators and Study Members; Québec Cardiovascular Study: Cantin B, Lamarche B, Després JP, Dagenais GR. Measures to assess the prognostic ability of the stratified Cox proportional hazards model.. Stat Med 2009; 28(3):389-411.
Després JP. Measuring waist circumference: Do not throw the baby out with the bath water! (Editorial). Heart 2010; 96(4):310.
The Emerging Risk Factors Collaboration; Investigators/Contributors; Québec Cardiovascular Study: Cantin B, Lamarche B, Després JP, Dagenais GR. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis.. Lancet 2010; 375(9709):132-40.
Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration; Québec Cardiovascular Study: Cantin B, Lamarche B, Després JP, Dagenais GR. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet 2010; 375(9726):1634-9.
Bertrand OF, Poirier P, Rodés-Cabau J, Rinfret S, Title LM, Dzavik V, Natarajan M, Angel J, Batalla N, Alméras N, Costerousse O, De Larochellière R, Roy L, Després JP; VICTORY Trial Investigators.. Cardiometabolic effects of rosiglitazone in patients with type 2 diabetes and coronary artery bypass grafts: A randomized placebo-controlled clinical trial.. Atherosclerosis 2010; 211(2):565-73.
Côté N, Pibarot P, Pépin A, Fournier D, Audet A, Arsenault B, Couture C, Poirier P, Després JP, Mathieu P. Oxidized low-density lipoprotein, angiotensin II and increased waist cirumference are associated with valve inflammation in prehypertensive patients with aortic stenosis.. Int J Cardiol 2010; 145(3):444-9.
Rana JS, Visser ME, Arsenault BJ, Després JP, Stroes ES, Kastelein JJ, Wareham NJ, Boekholdt SM, Khaw KT. Metabolic dyslipidemia and risk of future coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.. Int J Cardiol 2010; 143(3):399-404.
Mohty D, Pibarot P, Després JP, Cartier A, Arsenault B, Picard F, Mathieu P. Age-related differences in the pathogenesis of calcific aortic stenosis: the potential role of resistin.. Int J Cardiol 2010; 142(2):126-32.
de Graaf FR, Schuijf JD, Scholte AJ, Djaberi R, van Velzen JE, Roos CJ, Kroft LJ, de Roos A, van der Wall EE, Wouter Jukema J, Després JP, Bax JJ. Usefulness of hypertriglyceridemic waist phenotype in type 2 diabetes mellitus to predict the presence of coronary artery disease as assessed by computed tomographic coronary angiography.. Am J Cardiol 2010; 106(12):1747-53.
Chaput JP, Sjödin AM, Astrup A, Després JP, Bouchard C, Tremblay A. Risk factors for adult overweight and obesity: the importance of looking beyond the 'big two'.. Obes Facts 2010; 3(5):320-7.
Arsenault BJ, Després JP, Stroes ES, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM. Lipid assessment, metabolic syndrome and coronary heart disease risk.. Eur J Clin Invest 2010; 40(12):1081-93.
Malik VS, Popkin BM, Bray GA, Després JP, Willett WC, Hu FB. Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis.. Diabetes Care 2010; 33(11):2477-83.
Arsenault BJ, Lemieux I, Després JP, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM. The hypertriglyceridemic-waist phenotype and the risk of coronary artery disease: results from the EPIC-Norfolk prospective population study.. CMAJ 2010; 182(13):1427-32.
Charansonney OL, Després JP. Disease prevention--should we target obesity or sedentary lifestyle?. Nat Rev Cardiol 2010; 7(8):468-72.
Gallant AR, Tremblay A, Pérusse L, Bouchard C, Després JP, Drapeau V. The Three-Factor Eating Questionnaire and BMI in adolescents: results from the Québec family study.. Br J Nutr 2010; 104(7):1074-9.
Pagé A, Dumesnil JG, Clavel MA, Chan KL, Teo KK, Tam JW, Mathieu P, Després JP, Pibarot P, . Metabolic syndrome is associated with more pronounced impairment of left ventricle geometry and function in patients with calcific aortic stenosis: a substudy of the ASTRONOMER (Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin).. J Am Coll Cardiol 2010; 55(17):1867-74.
Topol EJ, Bousser MG, Fox KA, Creager MA, Despres JP, Easton JD, Hamm CW, Montalescot G, Steg PG, Pearson TA, Cohen E, Gaudin C, Job B, Murphy JH, Bhatt DL, Poirier P; CRESCENDO Investigators.. Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial.. Lancet 2010; 376(9740):517-23.
Lessard A, Alméras N, Turcotte H, Tremblay A, Després JP, Boulet LP. Adiposity and pulmonary function: Relationship with body fat distribution and systemic inflammation.. Clin Invest Med 2011; 34(2):E64.
Rana JS, Arsenault BJ, Després JP, Côté M, Talmud PJ, Ninio E, Wouter Jukema J, Wareham NJ, Kastelein JJ, Khaw KT, Matthijs Boekholdt S. Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women.. Eur Heart J 2011; 32(3):336-44.
Dolley G, Lamarche B, Després JP, Bouchard C, Pérusse L, Vohl MC. Investigation of LRP8 gene in 1p31 QTL linked to LDL peak particle diameter in the Quebec family study.. Mol Genet Metab 2011; 102(4):448-52.
Leiter LA, Fitchett DH, Gilbert RE, Gupta M, Mancini GB, McFarlane PA, Ross R, Teoh H, Verma S, Anand S, Camelon K, Chow CM, Cox JL, Després JP, Genest J, Harris SB, Lau DC, Lewanczuk R, Liu PP, Lonn EM, McPherson R, Poirier P, Qaadri S, Rabasa-Lhoret R, Rabkin SW, Sharma AM, Steele AW, Stone JA, Tardif JC, Tobe S, Ur E (Cardiometabolic Risk Working Group: Executive Committee). Identification and management of cardiometabolic risk in Canada: a position paper by the cardiometabolic risk working group (executive summary).. Can J Cardiol 2011; 27(2):124-31.
Leiter LA, Fitchett DH, Gilbert RE, Gupta M, Mancini GB, McFarlane PA, Ross R, Teoh H, Verma S, Anand S, Camelon K, Chow CM, Cox JL, Després JP, Genest J, Harris SB, Lau DC, Lewanczuk R, Liu PP, Lonn EM, McPherson R, Poirier P, Qaadri S, Rabasa-Lhoret R, Rabkin SW, Sharma AM, Steele AW, Stone JA, Tardif JC, Tobe S, Ur E (Cardiometabolic Risk Working Group: Executive Committee). Cardiometabolic risk in Canada: a detailed analysis and position paper by the cardiometabolic risk working group.. Can J Cardiol 2011; 27(2):e1-e33.
Broekhuizen LN, Boekholdt SM, Arsenault BJ, Despres JP, Stroes ES, Kastelein JJ, Khaw KT, Wareham NJ. Physical activity, metabolic syndrome, and coronary risk: the EPIC-Norfolk prospective population study.. Eur J Cardiovasc Prev Rehabil 2011; 18(2):209-17.
Lim S, Despres JP, Koh KK. Prevention of atherosclerosis in overweight/obese patients.. Circ J 2011; 75(5):1019-27.
Rhéaume C, Arsenault BJ, Dumas MP, Pérusse L, Tremblay A, Bouchard C, Poirier P, Després JP. Contributions of Cardiorespiratory Fitness and Visceral Adiposity to Six-Year Changes in Cardiometabolic Risk Markers in Apparently Healthy Men and Women.. J Clin Endocrinol Metab 2011; 96(5):1462-8.
Després JP. CRP: star trekking the galaxy of risk markers.. Lancet 2011; 377(9764):441-2.
Mothy D, Pibarot P, Cartier A, Côté M, Côté C, Després JP, Cosnay P, Mathieu P. Hypoadiponectinemia is associated with valvular inflammation and faster disease progression in patients with aortic stenosis.. Cardiology 2011; 118(2):140-6.
St-Pierre A, Cantin B, Lamarche B, Auger D, Després JP, Dagenais GR. Intermittent claudication: From its risk factors to its long-term prognosis in men. The Quebec Cardiovascular Study.. Can J Cardiol 2010; 26(1):17-21.
Emerging Risk Factors Collaboration, Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor DA, Selvin E, Stampfer M, Stehouwer CD, Lewington S, Pennells L, Thompson A, Sattar N, White IR, Ray KK, Danesh J (Cantin B, Després JP, Dagenais GR). Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.. Lancet 2010; 375(9733):2215-22.
Emerging Risk Factors Collaboration, Seshasai SR, Kaptoge S, Thompson A, Di Angelantonio E, Gao P, Sarwar N, Whincup PH, Mukamal KJ, Gillum RF, Holme I, Njølstad I, Fletcher A, Nilsson P, Lewington S, Collins R, Gudnason V, Thompson SG, Sattar N, Selvin E, Hu FB, Danesh J (Cantin B, Després JP, Dagenais GR). Diabetes mellitus, fasting glucose, and risk of cause-specific death.. N Engl J Med 2011; 364(9):829-41.
Després JP. Excess visceral adipose tissue/ectopic fat the missing link in the obesity paradox?. J Am Coll Cardiol 2011; 57(19):1887-9.
Chaput JP, Després JP, Bouchard C, Tremblay A. Longer sleep duration associates with lower adiposity gain in adult short sleepers.. Int J Obes 2012; 36(5):752-6.
Côté M, Cartier A, Reuwer AQ, Arsenault BJ, Lemieux I, Després JP, Wareham NJ, Kastelein JJ, Boekholdt SM, Khaw KT. Adiponectin and Risk of Coronary Heart Disease in Apparently Healthy Men and Women (from the EPIC-Norfolk Prospective Population Study).. Am J Cardiol 2011; 108(3):367-73.
Borel AL, Alméras N, Bergeron J, Tremblay A, Poirier P, Després JP. Lactivité physique réduit ladiposité viscérale indépendamment de la perte de poids/Physical activity reduces visceral adipose tissue independently of weight loss.. Méd mal métab 2010; 4(0):143-5.
Chaput JP, Després JP, Bouchard C, Tremblay A.. Short sleep duration preferentially increases abdominal adiposity in adults: preliminary evidence.. Clin Obesity 2011; 1(0):141-6.
Arsenault BJ, Beaumont EP, Després JP, Larose E. Mapping body fat distribution: A key step towards the identification of the vulnerable patient?. Ann Med 2012; 44(8):758-72.
Huot M, Arsenault BJ, Gaudreault V, Poirier P, Pérusse L, Tremblay A, Bouchard C, Després JP, Rhéaume C. Insulin resistance, low cardiorespiratory fitness, and increased exercise blood pressure: contribution of abdominal obesity.. Hypertension 2011; 58(6):1036-42.
Côté N, Couture C, Pibarot P, Després JP, Mathieu P. Angiotensin receptor blockers are associated with a lower remodelling score of stenotic aortic valves.. Eur J Clin Invest 2011; 41(11):1172-9.
Janiszewski PM, Ross R, Despres JP, Lemieux I, Orlando G, Carli F, Bagni P, Menozzi M, Zona S, Guaraldi G. Hypertriglyceridemia and waist circumference predict cardiovascular risk among HIV patients: a cross-sectional study.. PLoS One 2011; 6(9):e25032.
Chaput JP, Després JP, Bouchard C, Tremblay A. The association between short sleep duration and weight gain is dependent on disinhibited eating behavior in adults.. Sleep 2011; 34(10):1291-7.
Cornier MA, Després JP, Davis N, Grossniklaus DA, Klein S, Lamarche B, Lopez-Jimenez F, Rao G, St-Onge MP, Towfighi A, Poirier P; American Heart Association Obesity Committee of the Council on Nutrition; Physical Activity and Metabolism; Council on Arteriosclerosis; Thrombosis and Vascular Biology; Council on Cardiovascular Disease in the Young; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing, Council on Epidemiology and Prevention; Council on the Kidney in Cardiovascular Disease, and Stroke Council.. Assessing adiposity: a scientific statement from the american heart association.. Circulation 2011; 124(18):1996-2019.
Tonstad S, Després JP. Treatment of lipid disorders in obesity.. Expert Rev Cardiovasc Ther 2011; 9(8):1069-80.
Dallongeville J, Charbonnel B, Desprès JP. [Sugar-sweetened beverages and cardiometabolic risk].. Presse Med 2011; 40(10):910-5.
Dolley G, Boisclair ME, Lamarche B, Després JP, Bouchard C, Pérusse L, Vohl MC. Interactions between dietary fat intake and FASN genetic variation influence LDL peak particle diameter.. J Nutrigenet Nutrigenomics 2011; 4(3):137-45.
O'Leary DH, Reuwer AQ, Nissen SE, Després JP, Deanfield JE, Brown MW, Zhou R, Zabbatino SM, Job B, Kastelein JJ, Visseren FL, . Effect of rimonabant on carotid intima-media thickness (CIMT) progression in patients with abdominal obesity and metabolic syndrome: the AUDITOR Trial.. Heart 2011; 97(14):1143-50.
Gupta M, Martineau P, Tran T, Després JP, Gaw A, de Teresa E, Farsang C, Gensini GF, Leiter LA, Blanco-Colio LM, Egido J, Langer A. Low-Density Lipoprotein Cholesterol and High-Sensitivity C-Reactive Protein Lowering With Atorvastatin in Patients of South Asian Compared With European Origin: Insights From the Achieve Cholesterol Targets Fast With Atorvastatin Stratified Titration (ACTFAST) Study.. J Clin Pharmacol 2012; 52(6):850-8.
Mohty D, Coté N, Pibarot p, Fournier D, Pépin A, Audet A, Després JP, Mathieu P.. Reduced fetuin A plasma level is associated with faster stenosis progression increased valvular calcification in elderly patients with aortic stenosis.. J Clin Exp Cardiolog 2011; 2(0):147.
Côté N, El Husseini D, Pépin A, Guauque-Olarte S, Ducharme V, Bouchard-Cannon P, Audet A, Fournier D, Gaudreault N, Derbali H, McKee MD, Simard C, Després JP, Pibarot P, Bossé Y, Mathieu P. ATP acts as a survival signal and prevents the mineralization of aortic valve.. J Mol Cell Cardiol 2012; 52(5):1191-202.
Poliakova N, Després JP, Bergeron J, Alméras N, Tremblay A, Poirier P. Influence of obesity indices, metabolic parameters and age on cardiac autonomic function in abdominally obese men.. Metabolism 2012; 61(9):1270-9.
Borel AL, Leblanc X, Alméras N, Tremblay A, Bergeron J, Poirier P, Després JP, Series F. Sleep apnoea attenuates the effects of a lifestyle intervention programme in men with visceral obesity.. Thorax 2012; 67(8):735-41.
Smith JD, Borel AL, Nazare JA, Haffner SM, Balkau B, Ross R, Massien C, Alméras N, Després JP. Visceral Adipose Tissue Indicates the Severity of Cardiometabolic Risk in Patients with and without Type 2 Diabetes: Results from the INSPIRE ME IAA Study.. J Clin Endocrinol Metab 2012; 97(5):1517-25.
Pelletier-Beaumont E, Arsenault BJ, Alméras N, Bergeron J, Tremblay A, Poirier P, Després JP. Normalization of visceral adiposity is required to normalize plasma apolipoprotein B levels in response to a healthy eating/physical activity lifestyle modification program in viscerally obese men.. Atherosclerosis 2012; 221(2):577-82.
Borel AL, Nazare JA, Smith J, Alméras N, Tremblay A, Bergeron J, Poirier P, Després JP. Visceral and Not Subcutaneous Abdominal Adiposity Reduction Drives the Benefits of a 1-Year Lifestyle Modification Program.. Obesity (Silver Spring) 2012; 20(6):1223-33.
Borel AL, Nazare JA, Smith J, Alméras N, Tremblay A, Bergeron J, Poirier P, Després JP. Improvement in insulin sensitivity following a 1-year lifestyle intervention program in viscerally obese men: contribution of abdominal adiposity.. Metabolism 2012; 61(2):262-72.
Girerd N, Pibarot P, Daleau P, Voisine P, O'Hara G, Després JP, Mathieu P. Statins Reduce Short- and Long-Term Mortality Associated With Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting: Impact of Postoperative Atrial Fibrillation and Statin Therapy on Survival.. Clin Cardiol 2012; 35(7):430-6.
Shetty R, Girerd N, Côté N, Arsenault B, Després JP, Pibarot P, Mathieu P. Elevated proportion of small, dense low-density lipoprotein particles and lower adiponectin blood levels predict early structural valve degeneration of bioprostheses.. Cardiology 2012; 121(1):20-6.
Gallant AR, Tremblay A, Pérusse L, Després JP, Bouchard C, Drapeau V. Past dieting is related to rigid control and disinhibition in adolescents from the Québec Family Study.. Br J Nutr 2012; 108(11):1976-9.
Shea J, Diamandis EP, Sharma AM, Després JP, Ezzat S, Greenway F. The Obesity Epidemic.. Clin Chem 2012; 58(6):968-73.
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després JP. Hypertriglyceridemic waist: a simple clinical phenotype associated with coronary artery disease in women.. Metabolism 2012; 61(1):56-64.
Audet A, Côté N, Couture C, Bossé Y, Després JP, Pibarot P, Mathieu P. Amyloid substance within stenotic aortic valves promotes mineralization.. Histopathology 2012; 61(4):610-619.
Moustarah F, Gilbert A, Després JP, Tchernof A. Impact of gastrointestinal surgery on cardiometabolic risk.. Curr Atheroscler Rep 2012; 14(6):588-96.
Després JP. Body fat distribution and risk of cardiovascular disease: an update.. Circulation 2012; 126(10):1301-13.
Arsenault BJ, Després JP. HDL cholesterol is not HDL--don't judge the book by its cover.. Nat Rev Cardiol 2012; 9(10):557-8.
Després JP. Abdominal obesity and cardiovascular disease: is inflammation the missing link?. Can J Cardiol 2012; 28(6):642-52.
Chaput JP, McNeil J, Després JP, Bouchard C, Tremblay A. Short sleep duration is associated with greater alcohol consumption in adults.. Appetite 2012; 59(3):650-5.
Capoulade R, Clavel MA, Dumesnil JG, Chan KL, Teo KK, Tam JW, Côté N, Mathieu P, Després JP, Pibarot P. Impact of metabolic syndrome on progression of aortic stenosis: influence of age and statin therapy.. J Am Coll Cardiol 2012; 60(3):216-23.
Després JP. What is "metabolically healthy obesity"?: from epidemiology to pathophysiological insights.. J Clin Endocrinol Metab 2012; 97(7):2283-5.
Saunders TJ, Palombella A, McGuire KA, Janiszewski PM, Després JP, Ross R. Acute exercise increases adiponectin levels in abdominally obese men.. J Nutr Metab 2012; 2012(0):148729.
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després JP. Angiographically-assessed coronary artery disease associates with HDL particle size in women.. Atherosclerosis 2012; 223(2):359-64.
Nazare JA, Smith JD, Borel AL, Haffner SM, Balkau B, Ross R, Massien C, Alméras N, Després JP. Ethnic influences on the relations between abdominal subcutaneous and visceral adiposity, liver fat, and cardiometabolic risk profile: the International Study of Prediction of Intra-Abdominal Adiposity and Its Relationship With Cardiometabolic Risk/Intra-Abdominal Adiposity.. Am J Clin Nutr 2012; 96(4):714-26.
Emerging Risk Factors Collaboration, Di Angelantonio E, Gao P, Pennells L, Kaptoge S, Caslake M, Thompson A, Butterworth AS, Sarwar N, Wormser D, Saleheen D, Ballantyne CM, Psaty BM, Sundström J, Ridker PM, Nagel D, Gillum RF, Ford I, Ducimetiere P, Kiechl S, Koenig W, Dullaart RP, Assmann G, D'Agostino RB Sr, Dagenais GR, Cooper JA, Kromhout D, Onat A, Tipping RW, Gómez-de-la-Cámara A, Rosengren A, Sutherland SE, Gallacher J, Fowkes FG, Casiglia E, Hofman A, Salomaa V, Barrett-Connor E, Clarke R, Brunner E, Jukema JW, Simons LA, Sandhu M, Wareham NJ, Khaw KT, Kauhanen J, Salonen JT, Howard WJ, Nordestgaard BG, Wood AM, Thompson SG, Boekholdt SM, Sattar N, Packard C, Gudnason V, Danesh J, Tipping R, Ballantyne C, Hoogeveen R, Virani S, Ndumele C, Nambi V, Willeit J, Willeit P, Mayr A, Santer P, Kiechl S, Gallacher J, Yarnell J, Ben-Shlomo Y, Casiglia E, Tikhonoff V, Sutherland S, Nietert P, Keil J, Bachman D, Psaty B, Cushman M, Tracy R, Jenny N, Nordestgaard B, Tybjærg-Hansen A, Frikke-Schmidt R, Benn M, Kamstrup P, Gómez de la Cámara A, Gutiérrez-Fuentes J, Gómez Gerique J, Rubio Herrera M, Simons L, Friedlander Y, McCallum J, Fowkes FG, Price J, Lee A, Bolton J, Sandhu M, Wareham N, Khaw KT, Harald K, Jousilahti P, Vartiainen E, Salomaa V, D'Agostino R Sr, Wolf P, Vasan R, Benjamin E, Cremer P, Nagel D, Kauhanen J, Salonen J, Nyyssönen K, Tuomainen TP, Koenig W, Meisinger C, Döring A, Mraz W, Rosengren A, Wilhelmsen L, Lappas G, Gillum R, Kwagyan J, Cooper J, Bauer K, Dullaart R, Bakker S, Gansevoort R, van der Harst P, Hillege H, Ducimetiere P, Amouyel P, Arveiler D, Evans A, Ferrières J, Schulte H, Assmann G, Jukema J, Stott D, Westendorp R, Buckley B, Cantin B, Lamarche B, Després JP, Dagenais G, Barrett-Connor E, Wingard D, Daniels L, Gudnason V, Aspelund T, Sigurdsson G, Thorsson B, Eiriksdottir G, Witteman J, Kardys I, Dehghan A, Ikram M, Hofman A, Howard W, Howard B, Zhang Y, Best L, Umans J, Onat A, Can G, Sundström J, Lind L, Giedraitis V, Ingelsson E, Marmot M, Clarke R, Collins R, Fletcher A, Brunner E, Shipley M, Kivimaki M, Ridker P, Buring J, Rifai N, Cook N, Ford I, Robertson M, Feskens E, Geleijnse J, Kromhout D, Walker M, Watson S, Alexander M, Butterworth A, Di Angelantonio E, Franco O, Gao P, Gobin R, Gregson J, Haycock P, Kaptoge S, Pennells L, Saleheen D, Sanderson J, Sarwar N, Thompson A, Thompson S, Walker M, Watson S, Wood A, Wormser D, Zhao X, Danesh J.. Lipid-related markers and cardiovascular disease prediction.. JAMA 2012; 307(23):2499-2506.
Wormser D, Angelantonio ED, Kaptoge S, Wood AM, Gao P, Sun Q, Walldius G, Selmer R, Verschuren WM, Bueno-de-Mesquita HB, Engström G, Ridker PM, Njølstad I, Iso H, Holme I, Giampaoli S, Tunstall-Pedoe H, Gaziano JM, Brunner E, Kee F, Tosetto A, Meisinger C, Brenner H, Ducimetiere P, Whincup PH, Tipping RW, Ford I, Cremer P, Hofman A, Wilhelmsen L, Clarke R, Boer IH, Jukema JW, Ibañez AM, Lawlor DA, D'Agostino RB, Rodriguez B, Casiglia E, Stehouwer CD, Simons LA, Nietert PJ, Barrett-Connor E, Panagiotakos DB, Björkelund C, Strandberg TE, Wassertheil-Smoller S, Blazer DG, Meade TW, Welin L, Svärdsudd K, Woodward M, Nissinen A, Kromhout D, Jørgensen T, Tilvis RS, Guralnik JM, Rosengren A, Taylor JO, Kiechl S, Dagenais GR, Gerry F, Fowkes R, Wallace RB, Khaw KT, Shaffer JA, Visser M, Kauhanen J, Salonen JT, Gallacher J, Ben-Shlomo Y, Kitamura A, Sundström J, Wennberg P, Kiyohara Y, Daimon M, de la Cámara AG, Cooper JA, Onat A, Devereux R, Mukamal KJ, Dankner R, Knuiman MW, Crespo CJ, Gansevoort RT, Goldbourt U, Nordestgaard BG, Shaw JE, Mussolino M, Nakagawa H, Fletcher A, Kuller LH, Gillum RF, Gudnason V, Assmann G, Wald N, Jousilahti PR, Greenland P, Trevisan M, Ulmer H, Butterworth AS, Folsom AR, Davey-Smith G, Hu FB, Danesh J, Tipping RW, Ford CE, Simpson LM, Walldius G, Jungner I, Folsom AR, Demerath EW, Franceschini N, Lutsey PL, Panagiotakos DB, Pitsavos C, Chrysohoou C, Stefanadis C, Shaw JE, Atkins R, Zimmet PZ, Barr EL, Knuiman MW, Whincup PH, Wannamethee SG, Morris RW, Willeit J, Kiechl S, Weger S, Oberhollenzer F, Wald N, Ebrahim S, Lawlor DA, Gallacher J, Ben-Shlomo Y, Yarnell JW, Casiglia E, Tikhonoff V, Greenland P, Shay CM, Garside DB, Nietert PJ, Sutherland SE, Bachman DL, Keil JE, de Boer IH, Kizer JR, Psaty BM, Mukamal KJ, Nordestgaard BG, Tybjærg-Hansen A, Jensen GB, Schnohr P, Giampaoli S, Palmieri L, Panico S, Pilotto L, Vanuzzo D, de la Cámara AG, Simons LA, Simons J, McCallum J, Friedlander Y, Gerry F, Fowkes R, Price JF, Lee AJ, Taylor JO, Guralnik JM, Phillips CL, Wallace RB, Kohout FJ, Cornoni-Huntley JC, Guralnik JM, Blazer DG, Guralnik JM, Phillips CL, Phillips CL, Guralnik JM, Khaw KT, Wareham NJ, Brenner H, Schöttker B, Müller H, Rothenbacher D, Wennberg P, Jansson JH, Nissinen A, Donfrancesco C, Giampaoli S, Woodward M, Vartiainen E, Jousilahti PR, Harald K, Salomaa V, D'Agostino RB, Vasan RS, Fox CS, Pencina MJ, Daimon M, Oizumi T, Kayama T, Kato T, Bladbjerg EM, Jørgensen T, Møller L, Jespersen J, Dankner R, Chetrit A, Lubin F, Svärdsudd K, Eriksson H, Welin L, Lappas G, Rosengren A, Lappas G, Welin L, Svärdsudd K, Eriksson H, Lappas G, Bengtsson C, Lissner L, Björkelund C, Cremer P, Nagel D, Strandberg TE, Salomaa V, Tilvis RS, Miettinen TA, Tilvis RS, Strandberg TE, Kiyohara Y, Arima H, Doi Y, Ninomiya T, Rodriguez B, Dekker JM, Nijpels G, Stehouwer CD, Hu FB, Sun Q, Rimm EB, Willett WC, Iso H, Kitamura A, Yamagishi K, Noda H, Goldbourt U, Vartiainen E, Jousilahti PR, Harald K, Salomaa V, Kauhanen J, Salonen JT, Kurl S, Tuomainen TP, Poppelaars JL, Deeg DJ, Visser M, Meade TW, De Stavola BL, Hedblad B, Nilsson P, Engström G, Verschuren WM, Blokstra A, de Boer IH, Shea SJ, Meisinger C, Thorand B, Koenig W, Döring A, Verschuren WM, Blokstra A, Bueno-de-Mesquita HB, Wilhelmsen L, Rosengren A, Lappas G, Fletcher A, Nitsch D, Kuller LH, Grandits G, Tverdal A, Selmer R, Nystad W, Mussolino M, Gillum RF, Hu FB, Sun Q, Manson JE, Rimm EB, Hankinson SE, Meade TW, De Stavola BL, Cooper JA, Bauer KA, Davidson KW, Kirkland S, Shaffer JA, Shimbo D, Kitamura A, Iso H, Sato S, Holme I, Selmer R, Tverdal A, Nystad W, Nakagawa H, Miura K, Sakurai M, Ducimetiere P, Jouven X, Bakker SJ, Gansevoort RT, van der Harst P, Hillege HL, Crespo CJ, Garcia-Palmieri MR, Kee F, Amouyel P, Arveiler D, Ferrières J, Schulte H, Assmann G, Jukema JW, de Craen AJ, Sattar N, Stott DJ, Cantin B, Lamarche B, Després JP, Dagenais GR, Barrett-Connor E, Bergstrom J, Bettencourt RR, Buisson C, Gudnason V, Aspelund T, Sigurdsson G, Thorsson B, Trevisan M, Hofman A, Ikram MA, Tiemeier H, Witteman JC, Tunstall-Pedoe H, Tavendale R, Lowe GD, Woodward M, Devereux R, Yeh JL, Ali T, Calhoun D, Ben-Shlomo Y, Davey-Smith G, Onat A, Can G, Nakagawa H, Sakurai M, Nakamura K, Morikawa Y, Njølstad I, Mathiesen EB, Løchen ML, Wilsgaard T, Sundström J, Ingelsson E, Michaëlsson K, Cederholm T, Gaziano JM, Buring J, Ridker PM, Gaziano JM, Ridker PM, Ulmer H, Diem G, Concin H, Rodeghiero F, Tosetto A, Wassertheil-Smoller S, Manson JE, Marmot M, Clarke R, Fletcher A, Brunner E, Shipley M, Kivimaki M, Ridker PM, Buring J, Ford I, Robertson M, Ibañez AM, Feskens E, Geleijnse JM, Kromhout D, Walker M, Watson S, Alexander M, Butterworth AS, Angelantonio ED, Franco OH, Gao P, Gobin R, Haycock P, Kaptoge S, Seshasai SR, Lewington S, Pennells L, Rapsomaniki E, Sarwar N, Thompson A, Thompson SG, Walker M, Watson S, White IR, Wood AM, Wormser D, Zhao X, Danesh J.. Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. Int J Epidemiol 2012; 41(5):1419-1433.
Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, Pennells L, Wood AM, White IR, Gao P, Walker M, Thompson A, Sarwar N, Caslake M, Butterworth AS, Amouyel P, Assmann G, Bakker SJ, Barr EL, Barrett-Connor E, Benjamin EJ, Björkelund C, Brenner H, Brunner E, Clarke R, Cooper JA, Cremer P, Cushman M, Dagenais GR, D'Agostino RB Sr, Dankner R, Davey-Smith G, Deeg D, Dekker JM, Engström G, Folsom AR, Fowkes FG, Gallacher J, Gaziano JM, Giampaoli S, Gillum RF, Hofman A, Howard BV, Ingelsson E, Iso H, Jørgensen T, Kiechl S, Kitamura A, Kiyohara Y, Koenig W, Kromhout D, Kuller LH, Lawlor DA, Meade TW, Nissinen A, Nordestgaard BG, Onat A, Panagiotakos DB, Psaty BM, Rodriguez B, Rosengren A, Salomaa V, Kauhanen J, Salonen JT, Shaffer JA, Shea S, Ford I, Stehouwer CD, Strandberg TE, Tipping RW, Tosetto A, Wassertheil-Smoller S, Wennberg P, Westendorp RG, Whincup PH, Wilhelmsen L, Woodward M, Lowe GD, Wareham NJ, Khaw KT, Sattar N, Packard CJ, Gudnason V, Ridker PM, Pepys MB, Thompson SG, Danesh J, Kaptoge S, Di Angelantonio E, Pennells L, Wood AM, White IR, Gao P, Walker M, Thompson A, Sarwar N, Caslake M, Butterworth AS, Amouyel P, Assmann G, Bakker SJ, Barr EL, Barrett-Connor E, Benjamin EJ, Björkelund C, Brenner H, Brunner E, Clarke R, Cooper JA, Cremer P, Cushman M, Dagenais GR, D'Agostino RB Sr, Dankner R, Davey-Smith G, Deeg D, Dekker JM, Engström G, Folsom AR, Fowkes FG, Gallacher J, Gaziano JM, Giampaoli S, Gillum RF, Hofman A, Howard BV, Ingelsson E, Iso H, Jørgensen T, Kiechl S, Kitamura A, Kiyohara Y, Koenig W, Kromhout D, Kuller LH, Lawlor DA, Meade TW, Nissinen A, Nordestgaard BG, Onat A, Panagiotakos DB, Psaty BM, Rodriguez B, Rosengren A, Salomaa V, Kauhanen J, Salonen JT, Shaffer JA, Shea S, Ford I, Stehouwer CD, Strandberg TE, Tipping RW, Tosetto A, Wassertheil-Smoller S, Wennberg P, Westendorp RG, Whincup PH, Wilhelmsen L, Woodward M, Lowe GD, Wareham NJ, Khaw KT, Sattar N, Packard CJ, Gudnason V, Ridker PM, Pepys MB, Thompson SG, Danesh J, Tipping RW, Folsom AR, Chambless LE, Ballantyne CM, Astor BC, Panagiotakos DB, Pitsavos C, Chrysohoou C, Stefanadis C, Atkins R, Barr EL, Shaw JE, Zimmet PZ, Whincup PH, Wannamethee SG, Morris RW, Kiechl S, Willeit J, Mayr A, Schett G, Ebrahim S, Lawlor DA, Yarnell JW, Gallacher J, Cushman M, Psaty BM, Tracy R, Tybjærg-Hansen A, Frikke-Schmidt R, Benn M, Nordestgaard BG, Giampaoli S, Palmieri L, Panico S, Vanuzzo D, Pilotto L, Fowkes FG, Lee AJ, Khaw KT, Wareham NJ, Brenner H, Schöttker B, Müller H, Rothenbacher D, Jansson JH, Wennberg P, Nissinen A, Donfrancesco C, Giampaoli S, Salomaa V, Harald K, Jousilahti P, Vartiainen E, Woodward M, D'Agostino RB Sr, Wolf PA, Benjamin EJ, Pencina MJ, D'Agostino RB Sr, Wolf PA, Vasan RS, Benjamin EJ, Bladbjerg EM, Jørgensen T, Møller L, Jespersen J, Dankner R, Chetrit A, Lubin F, Wilhelmsen L, Eriksson H, Svärdsudd K, Welin L, Rosengren A, Wilhelmsen L, Lappas G, Eriksson H, Björkelund C, Lissner L, Bengtsson C, Cremer P, Nagel D, Tilvis RS, Strandberg TE, Kiyohara Y, Arima H, Doi Y, Ninomiya T, Rodriguez B, Dekker JM, Nijpels G, Stehouwer CD, Iso H, Kitamura A, Yamagishi K, Noda H, Kauhanen J, Salonen JT, Deeg D, Bremmer MA, Meade TW, Cooper JA, Hedblad B, Nilsson P, Engström G, Cushman M, Folsom AR, Psaty BM, Shea S, Döring A, Koenig W, Meisinger C, Wilhelmsen L, Rosengren A, Lappas G, Kuller LH, Grandits G, Gillum RF, Mussolino M, Meade TW, Cooper JA, Knottenbelt C, Cooper JA, Bauer KA, Davidson KW, Kirkland S, Shaffer JA, Shimbo D, Kitamura A, Iso H, Sato S, Bakker SJ, Gansevoort RT, Hillege HL, Amouyel P, Arveiler D, Evans A, Ferrières J, Schulte H, Assmann G, Packard CJ, Sattar N, Westendorp RG, Buckley BM, Cantin B, Lamarche B, Després JP, Dagenais GR, Barrett-Connor E, Wingard DL, Bettencourt R, Gudnason V, Aspelund T, Sigurdsson G, Thorsson B, Eiriksdottir G, Witteman J, Kardys I, Dehghan A, Hofman A, Tunstall-Pedoe H, Tavendale R, Lowe GD, Woodward M, Howard BV, Zhang Y, Best L, Umans J, Ben-Shlomo Y, Davey-Smith G, Onat A, Can G, Meade TW, Ingelsson E, Basu S, Cederholm T, Byberg L, Gaziano JM, Stampfer M, Ridker PM, Gaziano JM, Ridker PM, Tosetto A, Rodeghiero F, Wassertheil-Smoller S, Kaplan R, Kooperberg C, Marmot M, Clarke R, Collins R, Fletcher A, Brunner E, Shipley M, Kivimäki M, Ridker PM, Buring J, Cook N, Ford I, Shepherd J, Cobbe SM, Robertson M, Feskens EJ, Kromhout D, Walker M, Watson S, Alexander M, Butterworth AS, Di Angelantonio E, Franco OH, Gao P, Gobin R, Haycock P, Kaptoge S, Kondapally Seshasai SR, Lewington S, Pennells L, Rapsomaniki E, Sarwar N, Thompson A, Thompson SG, Walker M, Watson S, White IR, Wood AM, Wormser D, Zhao X, Danesh J.. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med 2012; 367(14):1310-1320.
Mahmut A, Boulanger MC, Fournier D, Couture C, Trahan S, Pagé S, Arsenault B, Després JP, Pibarot P, Mathieu P. Lipoprotein lipase in aortic valve stenosis is associated with lipid retention and remodelling.. Eur J Clin Invest 2013; 43(6):570-8.
Plourde M, Vohl MC, Bellis C, Carless M, Dyer T, Dolley G, Marette A, Després JP, Bouchard C, Blangero J, Pérusse L. A variant in the LRRFIP1 gene is associated with adiposity and inflammation.. Obesity (Silver Spring) 2013; 21(1):185-92.
Capoulade R, Clavel MA, Dumesnil JG, Chan KL, Teo KK, Tam JW, Côté N, Mathieu P, Després JP, Pibarot P. Insulin Resistance and LVH Progression in Patients With Calcific Aortic Stenosis: A Substudy of the ASTRONOMER Trial.. JACC Cardiovasc Imaging 2013; 6(2):165-74.
Teoh H, Després JP, Dufour R, Fitchett DH, Goldin L, Goodman SG, Harris SB, Langer A, Lau DC, Lonn EM, John Mancini GB, McFarlane PA, Poirier P, Rabasa-Lhoret R, Tan MK, Leiter LA. Identification and Management of Patients at Elevated Cardiometabolic Risk in Canadian Primary Care: How Well Are We Doing?. Can J Cardiol 2013; 29(8):960-8.
Després JP, Poirier P. Diabetes: Looking back at Look AHEAD-giving lifestyle a chance.. Nat Rev Cardiol 2013; 10(4):184-6.
Mahjoub H, Mathieu P, Sénéchal M, Larose E, Dumesnil J, Després JP, Pibarot P. ApoB/ApoA-I ratio is associated with increased risk of bioprosthetic valve degeneration.. J Am Coll Cardiol 2013; 61(7):752-61.
Gallant AR, Tremblay A, Pérusse L, Després JP, Bouchard C, Drapeau V. Parental eating behavior traits are related to offspring BMI in the Québec Family Study.. Int J Obes (Lond) 2013; 37(11):1422-6.
Saunders TJ, Tremblay MS, Després JP, Bouchard C, Tremblay A, Chaput JP. Sedentary behaviour, visceral fat accumulation and cardiometabolic risk in adults: a 6-year longitudinal study from the Quebec Family Study.. PLoS One 2013; 8(1):e54225.
Després JP. HDL cholesterol studies--more of the same?. Nat Rev Cardiol 2013; 10(2):70-2.
Tchernof A, Després JP. Pathophysiology of human visceral obesity: an update.. Physiol Rev 2013; 93(1):359-404.
Gaudreault V, Després JP, Rhéaume C, Alméras N, Bergeron J, Tremblay A, Poirier P. Exercise-induced hypertension in men with metabolic syndrome: anthropometric, metabolic, and hemodynamic features.. Metab Syndr Relat Disord 2013; 11(1):7-14.
Mauriège P, Imbeault P, Doucet E, Lacaille M, Langin D, Alméras N, Després JP, Tremblay A. Weight loss and regain in obese individuals: a link with adipose tissue metabolism indices?. J Physiol Biochem 2013; 69(3):497-505.
Smith J, Nazare JA, Borel AL, Aschner P, Barter PJ, Van Gaal L, Matsuzawa Y, Kadowaki T, Ross R, Brulle-Wohlhueter C, Alméras N, Haffner SM, Balkau B, Després JP. Assessment of cardiometabolic risk and prevalence of meeting treatment guidelines among patients with type 2 diabetes stratified according to their use of insulin and/or other diabetic medications: results from INSPIRE ME IAA.. Diabetes Obes Metab 2013; 15(7):629-41.
Riesco E, Tessier S, Lacaille M, Pérusse F, Côté M, Després JP, Bergeron J, Weisnagel JS, Doré J, Mauriège P.. Impact of a moderate-intensity walking program on cardiometabolic risk markers in overweight to obese women: is there any influence of menopause?. Menopause 2013; 20(2):185-193.
Huot M, Arsenault BJ, Gaudreault V, Poirier P, Pérusse L, Tremblay A, Bouchard C, Després JP, Rhéaume C.. Insulin resistance, low cardiorespiratory fitness, and increased exercise blood pressure: contribution of abdominal obesity. Hypertension 2011; 58(6):1036-1042.
Teoh H, Després JP, Dufour R, Fitchett DH, Goldin L, Goodman SG, Harris SB, Langer A, Lau DC, Lonn EM, Mancini GB, McFarlane PA, Poirier P, Rabasa-Lhoret R, Tan MK, Leiter LA.. A comparison of the assessment and management of cardiometabolic risk in patients with and without type 2 diabetes mellitus in Canadian primary care.. Diabetes Obes Metab 2013; 15(12):1093-100.
Delisle H, Ntandou G, Sodjinou R, Couillard C, Després JP.. At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study.. Nutrients 2013; 5(4):1366-83.
Laplante MA, Charbonneau A, Avramoglu RK, Pelletier P, Fang X, Bachelard H, Yla-Herttuala S, Laakso M, Despres JP, Deshaies Y, Sweeney G, Mathieu P, Marette A.. Distinct metabolic and vascular effects of dietary triglycerides and cholesterol in atherosclerotic and diabetic mouse models.. Am J Physiol Endocrinol Metab 2013; 305(5):E573-84.
Drapeau V, Blundell J, Gallant AR, Arguin H, Després JP, Lamarche B, Tremblay A.. Behavioural and metabolic characterisation of the low satiety phenotype.. Appetite 2013; 70(0):67-72.
O'Neill T, Guaraldi G, Orlando G, Carli F, Garlassi E, Zona S, Després JP, Ross R.. Combined use of waist and hip circumference to identify abdominally obese HIV-infected patients at increased health risk.. PLoS One 2013; 8(5):e62538.
Salamin G, Pelletier C, Poirier P, Bertrand OF, Després JP, Alméras N, Costerousse O, Brassard P. Impact of visceral obesity on cardiac parasympathetic activity in type 2 diabetics after coronary artery bypass graft surgery.. Obesity (Silver Spring) 2013; 21(8):1578-85.
Nazare JA, Smith J, Borel AL, Alméras N, Tremblay A, Bergeron J, Poirier P, Després JP.. Changes in both global diet quality and physical activity level synergistically reduce visceral adiposity in men with features of metabolic syndrome.. J Nutr 2013; 143(7):1074-83.
Borel AL, Boulet G, Nazare JA, Smith J, Alméras N, Tremblay A, Bergeron J, Poirier P, Carpentier AC, Després JP.. Improved Plasma FFA/Insulin Homeostasis Is Independently Associated With Improved Glucose Tolerance After a One-Year Lifestyle Intervention in Viscerally Obese Men.. Diabetes Care 2013; 36(10):3254-61.
Gaudreault V, Després JP, Rhéaume C, Bergeron J, Alméras N, Tremblay A, Poirier P.. Exercise-induced exaggerated blood pressure response in men with the metabolic syndrome: the role of the autonomous nervous system.. Blood Press Monit 2013; 18(5):252-8.
Arsenault BJ, Després JP, Boekholdt SM.. Hypertriglyceridemic waist: missing piece of the global cardiovascular risk assessment puzzle?. Clin Lipidol 2011; 6(6):639-51.
Chaput JP, McNeil J, Després JP, Bouchard C, Tremblay A.. Seven to eight hours of sleep a night is associated with a lower prevalence of the metabolic syndrome and reduced overall cardiometabolic risk in adults.. PLoS One 2013; 8(9):e72832.
Kraus WE, Bittner V, Appel L, Blair SN, Church T, Després JP, Franklin BA, Miller TD, Pate RR, Taylor-Piliae RE, Vafiadis DK, Whitsel L. The National Physical Activity Plan: A Call to Action From the American Heart Association: A Science Advisory From the American Heart Association.. Circulation 2015; 131(21):1932-40.
Chaput JP, McNeil J, Després JP, Bouchard C, Tremblay A.. Short sleep duration as a risk factor for the development of the metabolic syndrome in adults.. Prev Med 2013; 57(6):872-7.
Gaudreault V, Tizon-Marcos H, Poirier P, Pibarot P, Gilbert P, Amyot M, Rodés-Cabau J, Després JP, Bertrand OF, Larose É.. Transient Myocardial Tissue and Function Changes During a Marathon in Less Fit Marathon Runners.. Can J Cardiol 2013; 29(10):1269-76.
Lee HY, Després JP, Koh KK.. Perivascular adipose tissue in the pathogenesis of cardiovascular disease.. Atherosclerosis 2013; 230(2):177-84.
Capoulade R, Larose E, Mathieu P, Clavel MA, Dahou A, Arsenault M, Bédard E, Larue-Grondin S, Le Ven F, Dumesnil JG, Després JP, Pibarot P.. Visceral adiposity and left ventricular mass and function in patients with aortic stenosis: The PROGRESSA Study.. Can J Cardiol 2014; 30(9):1080-7.
Kohen Avramoglu R, Laplante MA, Le Quang K, Deshaies Y, Després JP, Larose E, Mathieu P, Poirier P, Pérusse L, Vohl MC, Sweeney G, Ylä-Herttuala S, Laakso M, Uusitupa M, Marette A. The genetic and metabolic determinants of cardiovascular complications in type 2 diabetes: recent insights from animal models and clinical investigations.. Can J Diabetes 2013; 37(5):351-8.
Mahmut A, Mahjoub H, Boulanger MC, Fournier D, Després JP, Pibarot P, Mathieu P. Lp-PLA2 is associated with structural valve degeneration of bioprostheses.. Eur J Clin Invest 2014; 44(2):136-45.
Chaput JP, McNeil J, Després JP, Bouchard C, Tremblay A. Correction: Seven to Eight Hours of Sleep a Night Is Associated with a Lower Prevalence of the Metabolic Syndrome and Reduced Overall Cardiometabolic Risk in Adults.. PLoS One 2013; 8(10):10.1371.
Rodés-Cabau J, Bertrand OF, Larose E, Déry JP, Rinfret S, Urena M, Jerez M, Nombela-Franco L, Ribeiro HB, Allende R, Proulx G, Nguyen CM, Boudreault JR, Rouleau J, Roy L, Gleeton O, Barbeau G, Noël B, Côté M, Després JP, Dagenais GR, DeLarochellière R. Five-year follow-up of the plaque sealing with paclitaxel-eluting stents vs medical therapy for the treatment of intermediate nonobstructive saphenous vein graft lesions (VELETI) trial.. Can J Cardiol 2014; 30(1):138-45.
Després JP, Alméras N, Gauvin L. Worksite health and wellness programs: Canadian achievements & prospects.. Prog Cardiovasc Dis 2014; 56(5):484-92.
Côté N, Mahmut A, Fournier D, Boulanger MC, Couture C, Després JP, Trahan S, Bossé Y, Pagé S, Pibarot P, Mathieu P. Angiotensin receptor blockers are associated with reduced fibrosis and interleukin-6 expression in calcific aortic valve disease.. Pathobiology 2014; 81(1):15-24.
Bastien M, Poirier P, Lemieux I, Després JP. Overview of epidemiology and contribution of obesity to cardiovascular disease.. Prog Cardiovasc Dis 2014; 56(4):369-81.
Villeneuve N, Pelletier-Beaumont E, Nazare JA, Lemieux I, Alméras N, Bergeron J, Tremblay A, Poirier P, Després JP. Interrelationships between changes in anthropometric variables and computed tomography indices of abdominal fat distribution in response to a 1-year physical activity-healthy eating lifestyle modification program in abdominally obese men.. Appl Physiol Nutr Metab 2014; 39(4):503-11.
De Larochellière E, Côté J, Gilbert G, Bibeau K, Ross MK, Dion-Roy V, Pibarot P, Després JP, Larose E. Visceral/epicardial adiposity in nonobese and apparently healthy young adults: Association with the cardiometabolic profile.. Atherosclerosis 2014; 234(1):23-9.
Gougeon R, Sievenpiper JL, Jenkins D, Yale JF, Bell R, Després JP, Ransom TP, Camelon K, Dupre J, Kendall C, Hegazi RA, Marchetti A, Hamdy O, Mechanick JI. The transcultural diabetes nutrition algorithm: a canadian perspective.. Int J Endocrinol 2014; 2014(0):151068.
Chaput JP, Pérusse L, Després JP, Tremblay A, Bouchard C. Findings from the Quebec Family Study on the Etiology of Obesity: Genetics and Environmental Highlights.. Curr Obes Rep 2014; 3(0):54-66.
Capoulade R, Chan KL, Yeang C, Mathieu P, Bossé Y, Dumesnil JG, Tam JW, Teo KK, Mahmut A, Yang X, Witztum JL, Arsenault BJ, Després JP, Pibarot P, Tsimikas S. Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis.. J Am Coll Cardiol 2015; 66(11):1236-46.
Harrington RA, Arena R, Després JP, Ciarochi A, Croll E, Bloch KD. More than 10 million steps in the right direction: results from the first american heart association scientific sessions walking challenge.. Prog Cardiovasc Dis 2015; 57(4):296-8.
Arena R, Harrington RA, Després JP. A message from modern-day healthcare to physical activity and fitness: welcome home!. Prog Cardiovasc Dis 2015; 57(4):293-5.
Myers J, McAuley P, Lavie CJ, Despres JP, Arena R, Kokkinos P. Physical activity and cardiorespiratory fitness as major markers of cardiovascular risk: their independent and interwoven importance to health status.. Prog Cardiovasc Dis 2015; 57(4):306-14.
Ross R, Blair S, de Lannoy L, Després JP, Lavie CJ. Changing the endpoints for determining effective obesity management.. Prog Cardiovasc Dis 2015; 57(4):330-6.
Mahjoub H, Mathieu P, Larose É, Dahou A, Sénéchal M, Dumesnil JG, Després JP, Pibarot P. Determinants of aortic bioprosthetic valve calcification assessed by multidetector CT.. Heart 2015; 101(6):472-7.
Mekary RA, Grøntved A, Despres JP, De Moura LP, Asgarzadeh M, Willett WC, Rimm EB, Giovannucci E, Hu FB. Weight training, aerobic physical activities, and long-term waist circumference change in men.. Obesity (Silver Spring) 2015; 23(2):461-7.
Després JP. Obesity and cardiovascular disease: weight loss is not the only target.. Can J Cardiol 2015; 31(2):216-22.
Nazare JA, Smith J, Borel AL, Aschner P, Barter P, Van Gaal L, Tan CE, Wittchen HU, Matsuzawa Y, Kadowaki T, Ross R, Brulle-Wohlhueter C, Alméras N, Haffner SM, Balkau B, Després JP. Usefulness of Measuring Both Body Mass Index and Waist Circumference for the Estimation of Visceral Adiposity and Related Cardiometabolic Risk Profile (from the INSPIRE ME IAA Study).. Am J Cardiol 2015; 115(3):307-15.
Capoulade R, Mahmut A, Tastet L, Arsenault M, Bédard É, Dumesnil JG, Després JP, Larose É, Arsenault BJ, Bossé Y, Mathieu P, Pibarot P. Impact of Plasma Lp-PLA2 Activity on the Progression of Aortic Stenosis: The PROGRESSA Study.. JACC Cardiovasc Imaging 2015; 8(1):26-33.
Gangloff A, Bergeron J, Pelletier-Beaumont E, Nazare JA, Smith J, Borel AL, Lemieux I, Tremblay A, Poirier P, Alméras N, Després JP. Effect of adipose tissue volume loss on circulating 25-hydroxyvitamin D levels: results from a 1-year lifestyle intervention in viscerally obese men.. Int J Obes (Lond) 2015; 39(11):1638-43.
Carter S, Li Z, Lemieux I, Alméras N, Tremblay A, Bergeron J, Poirier P, Deshaies Y, Després JP, Picard F.. Circulating IGFBP-2 levels are incrementally linked to correlates of the metabolic syndrome and independently associated with VLDL triglycerides.. Atherosclerosis 2014; 237(2):645-51.
Arsenault BJ, Pelletier-Beaumont E, Alméras N, Tremblay A, Poirier P, Bergeron J, Després JP.. PCSK9 levels in abdominally obese men: association with cardiometabolic risk profile and effects of a one-year lifestyle modification program.. Atherosclerosis 2014; 236(2):321-6.
Lévesque V, Vallières M, Poirier P, Després JP, Alméras N.. Targeting Abdominal Adiposity and Cardiorespiratory Fitness in the Workplace.. Med Sci Sports Exerc 2015; 47(7):1342-50.
Punthakee Z, Alméras N, Després JP, Dagenais GR, Anand SS, Hunt DL, Sharma AM, Jung H, Yusuf S, Gerstein HC. Impact of rosiglitazone on body composition, hepatic fat, fatty acids, adipokines and glucose in persons with impaired fasting glucose or impaired glucose tolerance: a sub-study of the DREAM trial.. Diabet Med 2014; 31(9):1086-92.
Mahmut A, Boulanger MC, El Husseini D, Fournier D, Bouchareb R, Després JP, Pibarot P, Bossé Y, Mathieu P. Elevated expression of lipoprotein-associated phospholipase A2 in calcific aortic valve disease: implications for valve mineralization.. J Am Coll Cardiol 2014; 63(5):460-9.
Capoulade R, Côté N, Mathieu P, Chan KL, Clavel MA, Dumesnil JG, Teo KK, Tam JW, Fournier D, Després JP, Pibarot P. Circulating levels of matrix gla protein and progression of aortic stenosis: a substudy of the Aortic Stenosis Progression Observation: Measuring Effects of rosuvastatin (ASTRONOMER) trial.. Can J Cardiol 2014; 30(9):1088-95.
Mathieu P, Boulanger MC, Després JP. Ectopic visceral fat: a clinical and molecular perspective on the cardiometabolic risk.. Rev Endocr Metab Disord 2014; 15(4):289-98.
Rhéaume C, Arsenault BJ, Després JP, Faha, Boekholdt SM, Wareham NJ, Khaw KT, Chir M. Impact of abdominal obesity and systemic hypertension on risk of coronary heart disease in men and women: the EPIC-Norfolk Population Study.. J Hypertens 2014; 32(11):2224-30; discussio.
Després JP. Waist circumference as a vital sign in cardiology 20 years after its initial publication in the American Journal of Cardiology.. Am J Cardiol 2014; 114(2):320-3.
Borel AL, Nazare JA, Smith J, Aschner P, Barter P, Van Gaal L, Eng Tan C, Wittchen HU, Matsuzawa Y, Kadowaki T, Ross R, Brulle-Wohlhueter C, Alméras N, Haffner SM, Balkau B, Després JP. Visceral, subcutaneous abdominal adiposity and liver fat content distribution in normal glucose tolerance, impaired fasting glucose and/or impaired glucose tolerance.. Int J Obes (Lond) 2015; 39(3):495-501.
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, de Ferranti S, Després JP, Fullerton HJ, Howard VJ, Huffman MD, Judd SE, Kissela BM, Lackland DT, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Matchar DB, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Willey JZ, Woo D, Yeh RW, Turner MB. Heart disease and stroke statistics--2015 update: a report from the American Heart Association.. Circulation 2015; 131(4):e29-322.
Sung YJ, Pérusse L, Sarzynski MA, Fornage M, Sidney S, Sternfeld B, Rice T, Terry JG, Jacobs DR, Katzmarzyk P, Curran JE, Carr JJ, Blangero J, Ghosh S, Després JP, Rankinen T, Rao DC, Bouchard C. Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.. Int J Obes (Lond) 2016; 40(4):662-74.
Sperling LS, Mechanick JI, Neeland IJ, Herrick CJ, Després JP, Ndumele CE, Vijayaraghavan K, Handelsman Y, Puckrein GA, Araneta MR, Blum QK, Collins KK, Cook S, Dhurandhar NV, Dixon DL, Egan BM, Ferdinand DP, Herman LM, Hessen SE, Jacobson TA, Pate RR, Ratner RE, Brinton EA, Forker AD, Ritzenthaler LL, Grundy SM. The CardioMetabolic Health Alliance: Working Toward a New Care Model for the Metabolic Syndrome.. J Am Coll Cardiol 2015; 66(9):1050-67.
Buchan DS, Boddy LM, Despres JP, Grace FM, Sculthorpe N, Mahoney C, Baker JS. Utility of the hypertriglyceridemic waist phenotype in the cardiometabolic risk assessment of youth stratified by body mass index.. Pediatr Obes 2015; 0(0):Epub.
Rudkowska I, Pérusse L, Bellis C, Blangero J, Després JP, Bouchard C, Vohl MC. Interaction between Common Genetic Variants and Total Fat Intake on Low-Density Lipoprotein Peak Particle Diameter: A Genome-Wide Association Study.. J Nutrigenet Nutrigenomics 2015; 8(1):44-53.
Després JP, Nazare JA, Balkau B, Haffner SM, Brulle-Wohlhueter C. Reply: To PMID 25499404.. Am J Cardiol 2015; 116(2):336-7.
Lévesque V, Poirier P, Després JP, Alméras N. Assessing and targeting key lifestyle cardiovascular risk factors at the workplace: Effect on hemoglobin A1c levels.. Ann Med 2015; 47(7):605-14.
Auclair A, Martin J, Bastien M, Bonneville N, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Després JP, Poirier P. Is There a Role for Visceral Adiposity in Inducing Type 2 Diabetes Remission in Severely Obese Patients Following Biliopancreatic Diversion with Duodenal Switch Surgery?. Obes Surg 2015; 0(0):Epub.
Després JP. Physical Activity, Sedentary Behaviours, and Cardiovascular Health: When Will Cardiorespiratory Fitness Become a Vital Sign?. Can J Cardiol 2016; 32(4):505-13.
Kim SH, Després JP, Koh KK. Obesity and cardiovascular disease: friend or foe?. Eur Heart J 2015; 0(0):Epub.
Després JP. Exercise and energy balance: going to extremes to show that body weight is not the best outcome.. Am J Clin Nutr 2015; 102(6):1303-4.
Sarzynski MA, Burton J, Rankinen T, Blair SN, Church TS, Després JP, Hagberg JM, Landers-Ramos R, Leon AS, Mikus CR, Rao DC, Seip RL, Skinner JS, Slentz CA, Thompson PD, Wilund KR, Kraus WE, Bouchard C. The effects of exercise on the lipoprotein subclass profile: A meta-analysis of 10 interventions.. Atherosclerosis 2015; 243(2):364-72.
Chassé M, Mathieu P, Voisine P, Després JP, Pibarot P, Baillot R, Lellouche F, Poirier P. The Underestimated Belly Factor: Waist Circumference Is Linked to Significant Morbidity Following Isolated Coronary Artery Bypass Grafting.. Can J Cardiol 2016; 32(3):327-35.
Matikainen N, Björnson E, Söderlund S, Borén C, Eliasson B, Pietiläinen KH, Bogl LH, Hakkarainen A, Lundbom N, Rivellese A, Riccardi G, Després JP, Alméras N, Holst JJ, Deacon CF, Borén J, Taskinen MR. Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men.. PLoS One 2016; 11(1):e0145890.
Tastet L, Capoulade R, Clavel MA, Larose É, Shen M, Dahou A, Arsenault M, Mathieu P, Bédard É, Dumesnil JG, Tremblay A, Bossé Y, Després JP, Pibarot P. Systolic hypertension and progression of aortic valve calcification in patients with aortic stenosis: results from the PROGRESSA study.. Eur Heart J Cardiovasc Imaging 2017; 18(1):70-78.
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Després JP, Fullerton HJ, Howard VJ, Huffman MD, Isasi CR, Jiménez MC, Judd SE, Kissela BM, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Magid DJ, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Rosamond W, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Woo D, Yeh RW, Turner MB. Executive Summary: Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association.. Circulation 2016; 133(4):447-54.
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Després JP, Fullerton HJ, Howard VJ, Huffman MD, Isasi CR, Jiménez MC, Judd SE, Kissela BM, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Magid DJ, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Rosamond W, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Woo D, Yeh RW, Turner MB. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association.. Circulation 2016; 133(4):e38-e360.
Poirier P, Marette A, Després JP, Larose E, Arsenault BJ.. Mortality in the Familial Atherosclerosis Treatment Study-Observational Study.. J Clin Lipidol 2017; 11(1):309-10.
Leclerc J, Arsenault M, Després JP, Brassard P, Gaudreault V, Bergeron J, Alméras N, Tremblay A, Auclair A, Ross MK, Denault-Bissonnette S, Poirier P. Determinants of Improvement In Left Ventricular Diastolic Function Following a 1-Year Lifestyle Modification Program in Abdominally Obese Men with Features of the Metabolic Syndrome.. Metab Syndr Relat Disord 2016; 14(10):483-491.
Grenier A, Brassard P, Bertrand OF, Després JP, Costerousse O, Alméras N, Poirier P. Rosiglitazone influences adipose tissue distribution without deleterious impact on heart rate variability in coronary heart disease patients with type 2 diabetes.. Clin Auton Res 2016; 26(6):407-14.
Auclair A, Martin J, Bastien M, Bonneville N, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Després JP, Poirier P. Is There a Role for Visceral Adiposity in Inducing Type 2 Diabetes Remission in Severely Obese Patients Following Biliopancreatic Diversion with Duodenal Switch Surgery?. Obes Surg 2016; 26(8):1717-27.
Nsaibia MJ, Mahmut A, Mahjoub H, Dahou A, Bouchareb R, Boulanger MC, Després JP, Bossé Y, Arsenault BJ, Larose E, Pibarot P, Mathieu P. Association between plasma lipoprotein levels and bioprosthetic valve structural degeneration.. Heart 2016; 102(23):1915-1921.
Després JP, De Larochellière R. Cardiovascular medicine at the Québec Heart and Lung Institute.. Eur Heart J 2016; 37(44):3307-3309.
Ross R, Blair SN, Arena R, Church TS, Després JP, Franklin BA, Haskell WL, Kaminsky LA, Levine BD, Lavie CJ, Myers J, Niebauer J, Sallis R, Sawada SS, Sui X, Wisløff U. Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association.. Circulation 2016; 134(24):e653-e699.
Gangloff A, Bergeron J, Lemieux I, Després JP. Changes in circulating vitamin D levels with loss of adipose tissue.. Curr Opin Clin Nutr Metab Care 2016; 19(6):464-470.
Anand SS, Tu JV, Awadalla P, Black S, Boileau C, Busseuil D, Desai D, Després JP, de Souza RJ, Dummer T, Jacquemont S, Knoppers B, Larose E, Lear SA, Marcotte F, Moody AR, Parker L, Poirier P, Robson PJ, Smith EE, Spinelli JJ, Tardif JC, Teo KK, Tusevljak N, Friedrich MG. Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) - a Pan Canadian cohort study.. BMC Public Health 2016; 16(0):650.
Côté JA, Nazare JA, Nadeau M, Leboeuf M, Blackburn L, Després JP, Tchernof A. Computed tomography-measured adipose tissue attenuation and area both predict adipocyte size and cardiometabolic risk in women.. Adipocyte 2016; 5(1):35-42.
Lamarche B, Givens DI, Soedamah-Muthu S, Krauss RM, Jakobsen MU, Bischoff-Ferrari HA, Pan A, Després JP. Does Milk Consumption Contribute to Cardiometabolic Health and Overall Diet Quality?. Can J Cardiol 2016; 32(8):1026-32.
Martin M, Almeras N, Després JP, Coxson HO, Washko GR, Vivodtzev I, Wouters EF, Rutten E, Williams MC, Murchison JT, MacNee W, Sin DD, Maltais F. Ectopic fat accumulation in patients with COPD: an ECLIPSE substudy.. Int J Chron Obstruct Pulmon Dis 2017; 12(0):451-460.
Kim SH, Després JP, Koh KK. Obesity and cardiovascular disease: friend or foe?. Eur Heart J 2016; 37(48):3560-3568.
Buchan DS, Boddy LM, Despres JP, Grace FM, Sculthorpe N, Mahoney C, Baker JS. Utility of the hypertriglyceridemic waist phenotype in the cardiometabolic risk assessment of youth stratified by body mass index.. Pediatr Obes 2016; 11(4):292-8.
Borel AL, Nazare JA, Baillot A, Alméras N, Tremblay A, Bergeron J, Poirier P, Després JP. Cardiometabolic risk improvement in response to a 3-yr lifestyle modification program in men: contribution of improved cardiorespiratory fitness vs. weight loss.. Am J Physiol Endocrinol Metab 2017; 312(4):E273-E281.
González-Muniesa P, Mártinez-González MA, Hu FB, Després JP, Matsuzawa Y, Loos RJF, Moreno LA, Bray GA, Martinez JA. Obesity.. Nat Rev Dis Primers 2017; 3(0):17034.
Capoulade R, Chan KL, Mathieu P, Bossé Y, Dumesnil JG, Tam JW, Teo KK, Yang X, Witztum JL, Arsenault BJ, Després JP, Pibarot P, Tsimikas S. Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial.. Atherosclerosis 2017; 260(0):1-7.
Després JP. Overweight: The Body Mass Index Category With an Identity Crisis.. Ann Intern Med 2017; 166(9):671-2.
Arsenault BJ, Lamarche B, Després JP. Targeting Overconsumption of Sugar-Sweetened Beverages vs. Overall Poor Diet Quality for Cardiometabolic Diseases Risk Prevention: Place Your Bets!. Nutrients 2017; 9(6):E600.
de Toro-Martín J, Arsenault BJ, Després JP, Vohl MC. Precision Nutrition: A Review of Personalized Nutritional Approaches for the Prevention and Management of Metabolic Syndrome.. Nutrients 2017; 9(8):E913.
Matikainen N, Söderlund S, Björnson E, Bogl LH, Pietiläinen KH, Hakkarainen A, Lundbom N, Eliasson B, Räsänen SM, Rivellese A, Patti L, Prinster A, Riccardi G, Després JP, Alméras N, Holst JJ, Deacon CF, Borén J, Taskinen MR. Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men.. Nutr Metab Cardiovasc Dis 2017; 27(6):534-542.
Arsenault BJ, Després JP.. Cardiovascular disease prevention: lifestyle attenuation of genetic risk.. Nat Rev Cardiol 2017; 14(4):187-8.
Panahi S, Doyon CY, Després JP, Pérusse L, Vohl MC, Drapeau V, Tremblay A. Yogurt consumption, body composition, and metabolic health in the Québec Family Study.. Eur J Nutr 2018; 57(4):1591-1603.
LeBlanc S, Bibeau K, Bertrand OF, Lévesque V, Deschênes St-Pierre B, Pibarot P, Després JP, Larose E.. Carotid versus coronary atherosclerosis burdens in acute compared with chronic symptomatic coronary artery disease.. Can J Physiol Pharmacol 2017; 95(8):878-87.
Arguin H, Tremblay A, Blundell JE, Després JP, Richard D, Lamarche B, Drapeau V. Impact of a non-restrictive satiating diet on anthropometrics, satiety responsiveness and eating behaviour traits in obese men displaying a high or a low satiety phenotype.. Br J Nutr 2017; 118(9):750-760.
Lévesque V, Poirier P, Després JP, Alméras N. Relation Between a Simple Lifestyle Risk Score and Established Biological Risk Factors for Cardiovascular Disease.. Am J Cardiol 2017; 120(11):1939-1946.
Tastet L, Capoulade R, Shen M, Clavel MA, Côté N, Mathieu P, Arsenault M, Bédard É, Tremblay A, Samson M, Bossé Y, Dumesnil JG, Arsenault BJ, Beaudoin J, Bernier M, Després JP, Pibarot P. ApoB/ApoA-I Ratio is Associated With Faster Hemodynamic Progression of Aortic Stenosis: Results From the PROGRESSA (Metabolic Determinants of the Progression of Aortic Stenosis) Study.. J Am Heart Assoc 2018; 7(4):e007980.
Taskinen MR, Söderlund S, Bogl LH, Hakkarainen A, Matikainen N, Pietiläinen KH, Räsänen S, Lundbom N, Björnson E, Eliasson B, Mancina RM, Romeo S, Alméras N, Pepa GD, Vetrani C, Prinster A, Annuzzi G, Rivellese A, Després JP, Borén J.. Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity.. J Intern Med 2017; 282(2):187-201.
LeBlanc S, Coulombe F, Bertrand OF, Bibeau K, Pibarot P, Marette A, Alméras N, Lemieux I, Després JP, Larose E.. Hypertriglyceridemic Waist: A Simple Marker of High-Risk Atherosclerosis Features Associated With Excess Visceral Adiposity/Ectopic Fat.. J Am Heart Assoc 2018; 7(8):e008139.
Maltais A, Alméras N, Lemieux I, Tremblay A, Bergeron J, Poirier P, Després JP.. Trunk muscle quality assessed by computed tomography: Association with adiposity indices and glucose tolerance in men. Metabolism 2018; 85(0):205-212.
Piché ME, Laberge AS, Brassard P, Arsenault BJ, Costerousse O, Bertrand OF, Després JP, Poirier P. Rosiglitazone lowers resting and blood pressure response to exercise in men with type 2 diabetes: A 1-year randomized study.. Diabetes Obes Metab 2018; 20(7):1740-1750.
Chau K, Girerd N, Magnusson M, Lamiral Z, Bozec E, Merckle L, Leosdottir M, Bachus E, Frikha Z, Ferreira J, Després JP, Rossignol P, Boivin JM, Zannad F.. Obesity and metabolic features associated with long-term developing diastolic dysfunction in an initially healthy population-based cohort.. Clin Res Cardiol 2018; 107(10):887-896.
Neeland IJ, Poirier P, Després JP.. Cardiovascular and Metabolic Heterogeneity of Obesity: Clinical Challenges and Implications for Management.. Circulation 2018; 137(13):1391-1406.
Wood AM, Kaptoge S, Butterworth AS, Willeit P, Warnakula S, Bolton T, Paige E, Paul DS, Sweeting M, Burgess S, Bell S, Astle W, Stevens D, Koulman A, Selmer RM, Verschuren WMM, Sato S, Njølstad I, Woodward M, Salomaa V, Nordestgaard BG, Yeap BB, Fletcher A, Melander O, Kuller LH, Balkau B, Marmot M, Koenig W, Casiglia E, Cooper C, Arndt V, Franco OH, Wennberg P, Gallacher J, de la Cámara AG, Völzke H, Dahm CC, Dale CE, Bergmann MM, Crespo CJ, van der Schouw YT, Kaaks R, Simons LA, Lagiou P, Schoufour JD, Boer JMA, Key TJ, Rodriguez B, Moreno-Iribas C, Davidson KW, Taylor JO, Sacerdote C, Wallace RB, Quiros JR, Tumino R, Blazer DG 2nd, Linneberg A, Daimon M, Panico S, Howard B, Skeie G, Strandberg T, Weiderpass E, Nietert PJ, Psaty BM, Kromhout D, Salamanca-Fernandez E, Kiechl S, Krumholz HM, Grioni S, Palli D, Huerta JM, Price J, Sundström J, Arriola L, Arima H, Travis RC, Panagiotakos DB, Karakatsani A, Trichopoulou A, Kühn T, Grobbee DE, Barrett-Connor E, van Schoor N, Boeing H, Overvad K, Kauhanen J, Wareham N, Langenberg C, Forouhi N, Wennberg M, Després JP, Cushman M, Cooper JA, Rodriguez CJ, Sakurai M, Shaw JE, Knuiman M, Voortman T, Meisinger C, Tjønneland A, Brenner H, Palmieri L, Dallongeville J, Brunner EJ, Assmann G, Trevisan M, Gillum RF, Ford I, Sattar N, Lazo M, Thompson SG, Ferrari P, Leon DA, Smith GD, Peto R, Jackson R, Banks E, Di Angelantonio E, Danesh J; Emerging Risk Factors Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group.. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.. Lancet 2018; 391(10129):1513-23.
Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X, White I, Burgess S, Willeit P, Bolton T, Moons KGM, van der Schouw YT, Selmer R, Khaw KT, Gudnason V, Assmann G, Amouyel P, Salomaa V, Kivimaki M, Nordestgaard BG, Blaha MJ, Kuller LH, Brenner H, Gillum RF, Meisinger C, Ford I, Knuiman MW, Rosengren A, Lawlor DA, Völzke H, Cooper C, Marín Ibañez A, Casiglia E, Kauhanen J, Cooper JA, Rodriguez B, Sundström J, Barrett-Connor E, Dankner R, Nietert PJ, Davidson KW, Wallace RB, Blazer DG, Björkelund C, Donfrancesco C, Krumholz HM, Nissinen A, Davis BR, Coady S, Whincup PH, Jørgensen T, Ducimetiere P, Trevisan M, Engström G, Crespo CJ, Meade TW, Visser M, Kromhout D, Kiechl S, Daimon M, Price JF, Gómez de la Cámara A, Wouter Jukema J, Lamarche B, Onat A, Simons LA, Kavousi M, Ben-Shlomo Y, Gallacher J, Dekker JM, Arima H, Shara N, Tipping RW, Roussel R, Brunner EJ, Koenig W, Sakurai M, Pavlovic J, Gansevoort RT, Nagel D, Goldbourt U, Barr ELM, Palmieri L, Njølstad I, Sato S, Monique Verschuren WM, Varghese CV, Graham I, Onuma O, Greenland P, Woodward M, Ezzati M, Psaty BM, Sattar N, Jackson R, Ridker PM, Cook NR, D'Agostino RB, Thompson SG, Danesh J, Di Angelantonio E; Emerging Risk Factors Collaboration (Després JP et Dagenais GR parmi les 170 collaborateurs). Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.. Eur Heart J 2019; 40(7):621-631.
Gregson J, Kaptoge S, Bolton T, Pennells L, Willeit P, Burgess S, Bell S, Sweeting M, Rimm EB, Kabrhel C, Zöller B, Assmann G, Gudnason V, Folsom AR, Arndt V, Fletcher A, Norman PE, Nordestgaard BG, Kitamura A, Mahmoodi BK, Whincup PH, Knuiman M, Salomaa V, Meisinger C, Koenig W, Kavousi M, Völzke H, Cooper JA, Ninomiya T, Casiglia E, Rodriguez B, Ben-Shlomo Y, Després JP, Simons L, Barrett-Connor E, Björkelund C, Notdurfter M, Kromhout D, Price J, Sutherland SE, Sundström J, Kauhanen J, Gallacher J, Beulens JWJ, Dankner R, Cooper C, Giampaoli S, Deen JF, Gómez de la Cámara A, Kuller LH, Rosengren A, Svensson PJ, Nagel D, Crespo CJ, Brenner H, Albertorio-Diaz JR, Atkins R, Brunner EJ, Shipley M, Njølstad I, Lawlor DA, van der Schouw YT, Selmer RM, Trevisan M, Verschuren WMM, Greenland P, Wassertheil-Smoller S, Lowe GDO, Wood AM, Butterworth AS, Thompson SG, Danesh J, Di Angelantonio E, Meade T. Cardiovascular Risk Factors Associated With Venous Thromboembolism.. JAMA Cardiol 2019; 4(2):163-173.
Rao S, Pandey A, Garg S, Park B, Mayo H, Després JP, Kumbhani D, de Lemos JA, Neeland IJ. Effect of Exercise and Pharmacological Interventions on Visceral Adiposity: A Systematic Review and Meta-analysis of Long-term Randomized Controlled Trials.. Mayo Clin Proc 2019; 94(2):211-224.
Boyer M, Mitchell PL, Poirier P, Alméras N, Tremblay A, Bergeron J, Després JP, Arsenault BJ. Impact of a one-year lifestyle modification program on cholesterol efflux capacities in men with abdominal obesity and dyslipidemia.. Am J Physiol Endocrinol Metab 2018; 315(4):E460-E468.
Salaun E, Mahjoub H, Dahou A, Mathieu P, Larose E, Després JP, Rodés-Cabau J, Arsenault BJ, Puri R, Clavel MA, Pibarot P. Hemodynamic Deterioration of Surgically Implanted Bioprosthetic Aortic Valves.. J Am Coll Cardiol 2018; 72(3):241-251.
Panahi S, Gallant A, Tremblay A, Pérusse L, Després JP, Drapeau V.. The relationship between yogurt consumption, body weight, and metabolic profiles in youth with a familial predisposition to obesity.. Eur J Clin Nutr 2019; 73(4):541-548.
Després JP.. The Reaven syndrome: a tribute to a giant.. Nat Rev Endocrinol 2018; 14(6):319-20.
Boyer M, Lévesque V, Poirier P, Marette A, Mitchell PL, Mora S, Mathieu P, Després JP, Larose E, Arsenault BJ. Longitudinal Changes in Cholesterol Efflux Capacities in Patients With Coronary Artery Disease Undergoing Lifestyle Modification Therapy.. J Am Heart Assoc 2018; 7(11):e008681.
Piché ME, Poirier P, Lemieux I, Després JP. Overview of Epidemiology and Contribution of Obesity and Body Fat Distribution to Cardiovascular Disease: An Update.. Prog Cardiovasc Dis 2018; 61(2):103-113.
Clément AA, Riesco E, Tessier S, Lacaille M, Pérusse F, Coté M, Després JP, Weisnagel J, Doré J, Joanisse DR, Mauriège P.. The relationship between adiposopathy and glucose-insulin homeostasis is not affected by moderate-intensity aerobic training in healthy women with obesity.. J Physiol Biochem 2018; 74(4):591-601.
Coats V, Després JP, Alméras N, Martin M, Sin DD, Rabasa-Lhoret R, Larose E, Tan WC, Bourbeau J, Maltais F. Ectopic adiposity and cardiometabolic health in COPD.. Int J Chron Obstruct Pulmon Dis 2018; 13(0):3331-3340.
Carter S, Lemieux I, Li Z, Alméras N, Tremblay A, Bergeron J, Poirier P, Després JP, Picard F. Changes in IGFBP-2 levels following a one-year lifestyle modification program are independently related to improvements in plasma apo B and LDL apo B levels.. Atherosclerosis 2019; 281(0):89-97.
Tejani S, McCoy C, Ayers CR, Powell-Wiley TM, Després JP, Linge J, Dahlqvist Leinhard O, Petersson M, Borga M, Neeland IJ.. Cardiometabolic Health Outcomes Associated With Discordant Visceral and Liver Fat Phenotypes: Insights From the Dallas Heart Study and UK Biobank.. Mayo Clin Proc 2022; 97(2):225-237.
Johnson RK, Lichtenstein AH, Anderson CAM, Carson JA, Després JP, Hu FB, Kris-Etherton PM, Otten JJ, Towfighi A, Wylie-Rosett J. Low-Calorie Sweetened Beverages and Cardiometabolic Health: A Science Advisory From the American Heart Association.. Circulation 2018; 138(9):e126-e140.
Neeland IJ, Poirier P, Després JP. Response by Neeland et al to Letter Regarding Article, "Cardiovascular and Metabolic Heterogeneity of Obesity: Clinical Challenges and Implications for Management".. Circulation 2018; 138(14):1496-1497.
Piché ME, Poirier P, Marette A, Mathieu P, Lévesque V, Bibeau K, Larose E, Després JP. Benefits of 1-Year Lifestyle Modification Program on Exercise Capacity and Diastolic Function Among Coronary Artery Disease Men With and Without Type 2 Diabetes.. Metab Syndr Relat Disord 2019; 17(3):149-159.
Neeland IJ, Ross R, Després JP, Matsuzawa Y, Yamashita S, Shai I, Seidell J, Magni P, Santos RD, Arsenault B, Cuevas A, Hu FB, Griffin B, Zambon A, Barter P, Fruchart JC, Eckel RH.. Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a joint position of the International Atherosclerosis Society and International Chair on Cardiometabolic Risk Working Group on Visceral Obesity.. Lancet Diabetes Endocrinol 2019; 7(9):715-725.
Fruchart JC1, Santos RD2, Yamashita S3, Libby P4; International Atherosclerosis Society/R3i Foundation Consensus Panel (Després JP parmi les 54 collaborateurs). Residual vascular risk in diabetes - Will the SPPARM alpha concept hold the key?. Diabetes Metab Syndr 2019; 13(4):2723-2725.
Buteau-Poulin D, Poirier P, Després JP, Alméras N. Assessing nutritional quality as a 'vital sign' of cardiometabolic health.. Br J Nutr 2019; 122(2):195-205.
Maltais A, Lemieux I, Alméras N, Tremblay A, Bergeron J, Poirier P, Després JP. One-Year Lifestyle Intervention, Muscle Lipids, and Cardiometabolic Risk.. Med Sci Sports Exerc 2019; 51(10):2156-2165.
Côté CE, Rhéaume C, Poirier P, Després JP, Alméras N. Deteriorated Cardiometabolic Risk Profile in Individuals With Excessive Blood Pressure Response to Submaximal Exercise.. Am J Hypertens 2019; 32(10):945-952.
Gangloff A, Bergeron J, Lemieux I, Tremblay A, Poirier P, Alméras N, Després JP. Relationships between circulating 25(OH) vitamin D, leptin levels and visceral adipose tissue volume: results from a 1-year lifestyle intervention program in men with visceral obesity.. Int J Obes (Lond) 2020; 44(2):280-288.
Viglino D, Martin M, Almeras N, Després JP, Coxson HO, Pépin JL, Vivodtzev I, Maltais F; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators.. Low Liver Density Is Linked to Cardiovascular Comorbidity in COPD: An ECLIPSE Cohort Analysis.. Int J Chron Obstruct Pulmon Dis 2019; 14(0):3053-3061.
Viglino D, Martin M, Piché ME, Brouillard C, Després JP, Alméras N, Tan WC, Coats V, Bourbeau J, Pépin JL, Maltais F. Metabolic profiles among COPD and controls in the CanCOLD population-based cohort.. PLoS One 2020; 15(4):e0231072.
Anand SS, Tu JV, Desai D, Awadalla P, Robson P, Jacquemont S, Dummer T, Le N, Parker L, Poirier P, Teo K, Lear SA, Yusuf S, Tardif JC, Marcotte F, Busseuil D, Després JP, Black SE, Kirpalani A, Parraga G, Noseworthy MD, Dick A, Leipsic J, Kelton D, Vena J, Thomas M, Schulze KM, Larose E, Moody AR, Smith EE, Friedrich MG; Canadian Alliance for Healthy Hearts and Minds Cohort. Cardiovascular risk scoring and magnetic resonance imaging detected subclinical cerebrovascular disease.. Eur Heart J Cardiovasc Imaging 2020; 21(6):692-700.
Fruchart JC, Santos RD, Aguilar-Salinas C, Aikawa M, Al Rasadi K, Amarenco P, Barter PJ, Ceska R, Corsini A, Després JP, Duriez P, Eckel RH, Ezhov MV, Farnier M, Ginsberg HN, Hermans MP, Ishibashi S, Karpe F, Kodama T, Koenig W, Krempf M, Lim S, Lorenzatti AJ, McPherson R, Nuñez-Cortes JM, Nordestgaard BG, Ogawa H, Packard CJ, Plutzky J, Ponte-Negretti CI, Pradhan A, Ray KK, Reiner , Ridker PM, Ruscica M, Sadikot S, Shimano H, Sritara P, Stock JK, Su TC, Susekov AV, Tartar A, Taskinen MR, Tenenbaum A, Tokgözoğlu LS, Tomlinson B, Tybjærg-Hansen A, Valensi P, Vrablík M, Wahli W, Watts GF, Yamashita S, Yokote K, Zambon A, Libby P.. The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.. Cardiovasc Diabetol 2019; 18(1):71.
Bastien M, Poirier P, Brassard P, Arsenault BJ, Bertrand OF, Després JP, Costerousse O, Piché ME. Effect of PPAR? agonist on aerobic exercise capacity in relation to body fat distribution in men with type 2 diabetes mellitus and coronary artery disease: a 1-yr randomized study.. Am J Physiol Endocrinol Metab 2019; 317(1):E65-E73.
Kris-Etherton PM, Petersen KS, Després JP, Anderson CAM, Deedwania P, Furie KL, Lear S, Lichtenstein AH, Lobelo F, Morris PB, Sacks FM, Ma J; American Heart Association Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular and Stroke Nursing; Stroke Council; Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; and Council on Hypertension.. Strategies for Promotion of a Healthy Lifestyle in Clinical Settings: Pillars of Ideal Cardiovascular Health: A Science Advisory From the American Heart Association.. Circulation 2021; 144(24):e495-e514.
Kris-Etherton PM, Petersen KS, Després JP, Braun L, de Ferranti SD, Furie KL, Lear SA, Lobelo F, Morris PB, Sacks FM; American Heart Association Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular and Stroke Nursing; Stroke Council; Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; and Council on Hypertension.. Special Considerations for Healthy Lifestyle Promotion Across the Life Span in Clinical Settings: A Science Advisory From the American Heart Association.. Circulation 2021; 144(24):e515-e532.
Capoulade R, Torzewski M, Mayr M, Chan KL, Mathieu P, Bossé Y, Dumesnil JG, Tam J, Teo KK, Burnap SA, Schmid J, Gobel N, Franke UFW, Sanchez A, Witztum JL, Yang X, Yeang C, Arsenault B, Després JP, Pibarot P, Tsimikas S. ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis.. Heart 2020; 106(10):738-745.
Chartrand DJ, Larose E, Poirier P, Mathieu P, Alméras N, Pibarot P, Lamarche B, Rhéaume C, Després JP. Visceral adiposity and liver fat as mediators of the association between cardiorespiratory fitness and plasma glucose-insulin homeostasis.. Am J Physiol Endocrinol Metab 2020; 319(3):E548-E556.
Nolin MA, Demers MF, Rauzier C, Bouchard RH, Cadrin C, Després JP, Roy MA, Alméras N, Picard F. Circulating IGFBP-2 levels reveal atherogenic metabolic risk in schizophrenic patients using atypical antipsychotics.. World J Biol Psychiatry 2021; 22(3):175-182.
Ross R, Neeland IJ, Yamashita S, Shai I, Seidell J, Magni P, Santos RD, Arsenault B, Cuevas A, Hu FB, Griffin BA, Zambon A, Barter P, Fruchart JC, Eckel RH, Matsuzawa Y, Després JP. Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity.. Nat Rev Endocrinol 2020; 16(3):177-189.
Després JP. From syndrome X to cardiometabolic risk: clinical and public health implications.. Proc Nutr Soc 2020; 79(1):4-10.
Lemieux I, Després JP. Metabolic Syndrome: Past, Present and Future.. Nutrients 2020; 12(11):3501.
Katzmarzyk PT, Ross R, Blair SN, Després JP. Should we target increased physical activity or less sedentary behavior in the battle against cardiovascular disease risk development?. Atherosclerosis 2020; 311(0):107-115.
Lim S, Lim H, Després JP. Collateral Damage of the COVID-19 Pandemic on Nutritional Quality and Physical Activity: Perspective from South Korea.. Obesity (Silver Spring) 2020; 28(10):1788-1790.
Gangloff A, Bergeron J, Lemieux I, Després JP. Adiposity, lifestyle and vitamin D levels: the quest for answers.. Int J Obes (Lond) 2020; 44(7):1628-1629.
Piché ME, Tchernof A, Després JP. Obesity Phenotypes, Diabetes, and Cardiovascular Diseases.. Circ Res 2020; 126(11):1477-1500.
Després JP. Predicting longevity using metabolomics: a novel tool for precision lifestyle medicine?. Nat Rev Cardiol 2020; 17(2):67-68.
Gallani MC, Proulx-Belhumeur A, Alméras N, Després JP, Doré M, Giguère JF.. Development and Validation of a Salt Food Frequency Questionnaire (FFQ-Na) and a Discretionary Salt Questionnaire (DSQ) for the Evaluation of Salt Intake among French-Canadian Population.. Nutrients 2020; 13(1):105.
Zeng Q, Wang L, Dong S, Zha X, Ran L, Li Y, Chen S, Gao J, Li S, Lu Y, Zhang Y, Xiao X, Li Y, Ma X, Gong X, Chen W, Yang Y, Du X, Chen B, Lv Y, Wu Y, Hong G, Pan Y, Jiao J, Yan Y, Qi H, Zhai J, Li K, Zhao K, Wu J, Liu S, Blake GM, Fu H, Fu X, Guo Z, Lemieux I, Després JP, Cheng X. CT-derived abdominal adiposity: Distributions and better predictive ability than BMI in a nationwide study of 59,429 adults in China.. Metabolism 2021; 115(0):154456.
Amil S, Lemieux I, Poirier P, Lamarche B, Després JP, Alméras N. Targeting Diet Quality at the Workplace: Influence on Cardiometabolic Risk.. Nutrients 2021; 13(7):2283.
Després JP, Carpentier AC, Tchernof A, Neeland IJ, Poirier P. Management of Obesity in Cardiovascular Practice: JACC Focus Seminar.. J Am Coll Cardiol 2021; 78(5):513-531.
Eslam M, Ahmed A, Després JP, Jha V, Halford JCG, Wei Chieh JT, Harris DCH, Nangaku M, Colagiuri S, Targher G, Joshi S, Byrne CD, Khunti K, Nguyen MH, Gish RG, George J. Incorporating fatty liver disease in multidisciplinary care and novel clinical trial designs for patients with metabolic diseases.. Lancet Gastroenterol Hepatol 2021; 6(9):743-753.
Després JP. Severe COVID-19 outcomes - the role of physical activity.. Nat Rev Endocrinol 2021; 17(8):451-452.
Powell-Wiley TM, Poirier P, Burke LE, Després JP, Gordon-Larsen P, Lavie CJ, Lear SA, Ndumele CE, Neeland IJ, Sanders P, St-Onge MP. Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association.. Circulation 2021; 143(21):e984-e1010.
Pelletier C, Gagnon MP, Alméras N, Després JP, Poirier P, Tremblay A, Chabot C, Rhéaume C. Using an activity tracker to increase motivation for physical activity in patients with type 2 diabetes in primary care: a randomized pilot trial.. Mhealth 2021; 7(0):59.
LeBlanc A, Baron M, Blouin P, Tarabulsy G, Routhier F, Mercier C, Despres JP, Hébert M, De Koninck Y, Cellard C, Collin-Vézina D, Côté N, Dionne É, Fleet R, Gagné MH, Isabelle M, Lessard L, Menear M, Merette C, Ouellet MC, Roy MA, Saint-Jacques MC, Savard C. For a structured response to the psychosocial consequences of the restrictive measures imposed by the global COVID-19 health pandemic: the MAVIPAN longitudinal prospective cohort study protocol.. BMJ Open 2022; 12(4):e048749.
Anand SS, Friedrich MG, Lee DS, Awadalla P, Després JP, Desai D, de Souza RJ, Dummer T, Parraga G, Larose E, Lear SA, Teo KK, Poirier P, Schulze KM, Szczesniak D, Tardif JC, Vena J, Zatonska K, Yusuf S, Smith EE. Evaluation of Adiposity and Cognitive Function in Adults.. JAMA Netw Open 2022; 5(2):e2146324.
Després JP. Taking a closer look at metabolically healthy obesity.. Nat Rev Endocrinol 2022; 18(3):131-132.
Chartrand DJ, Murphy-Després A, Alméras N, Lemieux I, Larose E, Després JP. Overweight, Obesity, and CVD Risk: a Focus on Visceral/Ectopic Fat.. Curr Atheroscler Rep 2022; 24(4):185-195.
Gagnon E, Pelletier W, Gobeil É, Bourgault J, Manikpurage HD, Maltais-Payette I, Abner E, Taba N, Esko T, Mitchell PL, Ghodsian N, Després JP, Vohl MC, Tchernof A, Thériault S, Arsenault BJ. Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases.. Commun Med (Lond) 2022; 2(0):130.
Sarzynski MA, Rice TK, Després JP, Pérusse L, Tremblay A, Stanforth PR, Tchernof A, Barber JL, Falciani F, Clish C, Robbins JM, Ghosh S, Gerszten RE, Leon AS, Skinner JS, Rao DC, Bouchard C. The HERITAGE Family Study: A Review of the Effects of Exercise Training on Cardiometabolic Health, with Insights into Molecular Transducers.. Med Sci Sports Exerc 2022; 54(5):S1-S43.
Waddell T, Bagur A, Cunha D, Thomaides-Brears H, Banerjee R, Cuthbertson DJ, Brown E, Cusi K, Després JP, Brady M. Greater ectopic fat deposition and liver fibroinflammation and lower skeletal muscle mass in people with type 2 diabetes.. Obesity (Silver Spring) 2022; 30(6):1231-1238.
Poulin G, Arbour N, Laprise C, Després JP.. La Chaire de recherche en santé durable du Fonds de recherche du Québec - Santé et la revue Science of Nursing and Health Practices / Science infirmière et pratiques en santé : des outils complémentaires de démocratisation de la santé / The Sustainable Health Research Chair of the Quebec Research Fund Health and the journal Science of Nursing and Health Practices / Science infirmière et pratiques en santé: Complementary Tools for the Democratization of Health.. Sci Nurs Health Pract 2023; 6(1):9-15.
Lavertu G, Diendere E, Légaré F, Vignon Zomahoun HT, Kodjo Toi A, Leblond M, Rheault N, Audet-Walsh E, Beaulieu MC, Ben Charif A, Blanchette V, Després JP, Gaudreau A, Rhéaume C, Tremblay MC, Paquette JS.. Fostering translational research in chronic disease management: a logic model proposal.. Translat Med Comm 2022; 7(0):13.
Paquette JS, Vignon Zomahoun HT, Diendere E, Lavertu G, Rheault N, Kodjo Toi A, Leblond M, Audet-Walsh E, Beaulieu MC, Ben Charif A, Blanchette V, Després JP, Gaudreau A, Rhéaume C, Tremblay MC, Légaré F.. Collaboration between biomedical research and community-based primary health care actors in chronic disease management: a scoping review.. Translat Med Comm 2022; 7(0):11.
Després JP. BMI versus obesity subtypes in the era of precision medicine.. Lancet Diabetes Endocrinol 2023; 11(6):382-384.
Edimo Dikobo SJ, Lemieux I, Poirier P, Després JP, Alméras N. Leisure-time physical activity is more strongly associated with cardiometabolic risk than occupational physical activity: Results from a workplace lifestyle modification program.. Prog Cardiovasc Dis 2023; 78(0):74-82.
Rauzier C, Chartrand DJ, Alméras N, Lemieux I, Larose E, Mathieu P, Pibarot P, Lamarche B, Rhéaume C, Poirier P, Després JP, Picard F. Associations of insulin-like growth factor binding protein-2 (IGFBP-2) with metabolic profile and hepatic fat deposition in asymptomatic men and women.. Am J Physiol Endocrinol Metab 2023; 325(1):E99-E105.
Waddell T, Namburete AIL, Duckworth P, Eichert N, Thomaides-Brears H, Cuthbertson DJ, Despres JP, Brady M. Bayesian networks and imaging-derived phenotypes highlight the role of fat deposition in COVID-19 hospitalisation risk.. Front Bioinform 2023; 3(0):1163430.
Arsenault BJ, Després JP. Physical Activity for Type 2 Diabetes Prevention: Some Is Better Than None, More Is Better, and Earliest Is Best.. Diabetes Care 2023; 46(6):1132-1134.
Lemieux I, Després JP. Weight gain with age and coronary atherosclerosis: Only the tip of a deadly iceberg.. Atherosclerosis 2023; 373(0):55-57.
Park D, Shin MJ, Després JP, Eckel RH, Tuomilehto J, Lim S. 20-Year Trends in Metabolic Syndrome Among Korean Adults From 2001 to 2020.. JACC Asia 2023; 3(3):491-502.
Paulin A, Manikpurage HD, Després JP, Thériault S, Arsenault BJ. Sex-Specific Impact of Body Weight on Atherosclerotic Cardiovascular Disease Incidence in Individuals With and Without Ideal Cardiovascular Health.. J Am Heart Assoc 2023; 12(13):e028502.
Rauzier C, Chartrand DJ, Alméras N, Lemieux I, Larose E, Mathieu P, Pibarot P, Lamarche B, Rhéaume C, Poirier P, Després JP, Picard F. Plasma IGFBP-2 levels reveal heterogeneity in hepatic fat content in adults with excess visceral adiposity.. Front Endocrinol (Lausanne) 2023; 14(0):1222101.
Crater GD, Lalonde K, Ravenelle F, Harvey M, Després JP. Effects of CB1R inverse agonist, INV-202, in patients with features of metabolic syndrome. A randomized, placebo-controlled, double-blind phase 1b study.. Diabetes Obes Metab 2023; 0(0):Epub.
Ndumele CE, Rangaswami J, Chow SL, Neeland IJ, Tuttle KR, Khan SS, Coresh J, Mathew RO, Baker-Smith CM, Carnethon MR, Despres JP, Ho JE, Joseph JJ, Kernan WN, Khera A, Kosiborod MN, Lekavich CL, Lewis EF, Lo KB, Ozkan B, Palaniappan LP, Patel SS, Pencina MJ, Powell-Wiley TM, Sperling LS, Virani SS, Wright JT, Rajgopal Singh R, Elkind MSV. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association.. Circulation 2023; 148(20):1606-1635.
Ndumele CE, Neeland IJ, Tuttle KR, Chow SL, Mathew RO, Khan SS, Coresh J, Baker-Smith CM, Carnethon MR, Després JP, Ho JE, Joseph JJ, Kernan WN, Khera A, Kosiborod MN, Lekavich CL, Lewis EF, Lo KB, Ozkan B, Palaniappan LP, Patel SS, Pencina MJ, Powell-Wiley TM, Sperling LS, Virani SS, Wright JT, Rajgopal Singh R, Elkind MSV, Rangaswami J. A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association.. Circulation 2023; 148(20):1636-1664.

Dr Jean-Pierre Després

Domaine de recherche

Description des travaux

Prix et distinctions

Publications

Soutenir la médecine de demain, maintenant.

Soutenir la médecine
de demain, maintenant.