- Accueil
- Chercheurs
- Dr Frédéric-Simon Hould
Clinicien(ne) chercheur(e)
Dr Frédéric-Simon Hould
Obésité-Métabolisme
Publications
79- Marceau P, Biron S, Lebel S, Marceau S, Hould FS, Simard S, Dumont M, Fitzpatrick LA. Does bone change after biliopancreatic diversion?. J Gastrointest Surg 2002; 6(5):690-8.
- Marceau P, Hould FS, Lebel S, Simon M, Biron S. Complications of combined gastric restrictive and malabsorptive procedures: part 2. Curr Surg 2003; 60(3):274-9.
- Marceau P, Kaufman D, Biron S, Hould FS, Lebel S, Marceau S, Kral JG. Outcome of pregnancies after biliopancreatic diversion.. Obes Surg 2004; 14(3):318-24.
- Biron S, Hould FS, Lebel S, Marceau S, Lescelleur O, Simard S, Marceau P. Twenty years of biliopancreatic diversion: what is the goal of the surgery?. Obes Surg 2004; 14(2):160-4.
- Kral JG, Thung SN, Biron S, Hould FS, Lebel S, Marceau S, Simard S, Marceau P. Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis.. Surgery 2004; 135(1):48-58.
- Poirier B, Baillot R, Bauset R, Dagenais F, Mathieu P, Simard S, Dionne B, Caouette M, Hould FS, Doyle D, Poirier P. [Abdominal complications associated with cardiac surgery. Review of a contemporary surgical experience and of a series done without extracorporeal circulation]. Can J Surg 2003; 46(3):176-82.
- Debigaré R, Côté CH, Hould FS, LeBlanc P, Maltais F. In vitro and in vivo contractile properties of the vastus lateralis muscle in males with COPD.. Eur Respir J 2003; 21(2):273-8.
- Simard B, Turcotte H, Marceau P, Biron S, Hould FS, Lebel S, Marceau S, Boulet LP. Asthma and sleep apnea in patients with morbid obesity: outcome after bariatric surgery.. Obes Surg 2004; 14(10):1381-8.
- Woods P, Paquette C, Martin J, Dumesnil JG, Marceau P, Marceau S, Biron S, Hould FS, Lescelleur O, Lebel S, Poirier P. Metabolic and cardiovascular improvements after biliopancreatic diversion in a severely obese patient.. Cardiovasc Diabetol 2004; 3(1):5.
- Nadreau E, Baraboi ED, Samson P, Blouin A, Hould FS, Marceau P, Biron S, Richard D. Effects of the biliopancreatic diversion on energy balance in the rat.. Int J Obes (Lond) 2006; 30(3):419-29.
- Vohl MC, Houde A, Lebel S, Hould FS, Marceau P. Effects of the peroxisome proliferator-activated receptor-gamma co-activator-1 Gly482Ser variant on features of the metabolic syndrome.. Mol Genet Metab 2005; 86(1):300-6.
- Duval K, Marceau P, Lescelleur O, Hould FS, Marceau S, Biron S, Lebel S, Pérusse L, Lacasse Y. Health-related quality of life in morbid obesity.. Obes Surg 2006; 16(0):574-9.
- Marceau P, Cabanac M, Frankham PC, Hould FS, Lebel S, Marceau S, Lescelleur O, Biron S. Accelerated satiation after duodenal switch.. Surgery for Obesity and Related Diseases 2005; 1(0):408-12.
- Boivin A, Brochu G, Marceau S, Marceau P, Hould FS, Tchernof A. Regional differences in adipose tissue metabolism in obese men.. Metabolism 2007; 56(4):533-40.
- Blouin K, Richard C, Brochu G, Hould FS, Lebel S, Marceau S, Biron S, Luu-The V, Tchernof A. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.. J Endocrinol 2006; 191(3):637-49.
- Bélanger C, Hould FS, Lebel S, Biron S, Brochu G, Tchernof A. Omental and subcutaneous adipose tissue steroid levels in obese men.. Steroids 2006; 71(8):674-82.
- Kral JG, Biron S, Simard S, Hould FS, Lebel S, Marceau S, Marceau P. Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years.. Pediatrics 2006; 118(6):1644-9.
- Marceau P, Biron S, Hould FS, Lebel S, Marceau S, Lescelleur O, Biertho L, Simard S. Duodenal Switch: Long-Term Results.. Obes Surg 2008; 0(0):Epub.
- Bouchard L, Tchernof A, Deshaies Y, Lebel S, Hould FS, Marceau P, Vohl MC. CYR61 polymorphisms are associated with plasma HDL-cholesterol levels in obese individuals.. Clin Genet 2007; 72(3):224-9.
- Nault I, Nadreau E, Paquet C, Brassard P, Marceau P, Marceau S, Biron S, Hould FS, Lebel S, Richard D, Poirier P. Impact of bariatric surgery-induced weight loss on heart rate variability.. Metabolism 2007; 56(10):1425-30.
- Marceau P, Biron S, Hould FS, Lebel S, Marceau S, Lescelleur O, Biertho L, Simard S. Duodenal switch improved the standard biliopancreatic diversion. A retrospective study.. Surg Obes Relat Dis 2008; 5(0):43-47.
- Marceau P, Biron S, Hould FS, Lebel S, Marceau S, Lescelleur O, Biertho L, Simard S. Duodenal switch improved standard biliopancreatic diversion: a retrospective study.. Surg Obes Relat Dis 2009; 5(1):43-7.
- Bouchard L, Faucher G, Tchernof A, Deshaies Y, Lebel S, Hould FS, Marceau P, Vohl MC. Comprehensive genetic analysis of the dipeptidyl peptidase-4 gene and cardiovascular disease risk factors in obese individuals.. Acta Diabetol 2009; 46(1):13-21.
- Smith J, Cianflone K, Biron S, Hould FS, Lebel S, Marceau S, Lescelleur O, Biertho L, Simard S, Kral JG, Marceau P. Effects of maternal surgical weight loss in mothers on intergenerational transmission of obesity.. J Clin Endocrinol Metab 2009; 94(11):4275-83.
- Biertho L, Hould FS, Lebel S, Biron S. Transoral endoscopic restrictive implant system: a new endoscopic technique for the treatment of obesity.. Surg Obes Relat Dis 2010; 6(2):203-5.
- Bouchard L, Vohl MC, Lebel S, Hould FS, Marceau P, Bergeron J, Pérusse L, Mauriège P. Contribution of genetic and metabolic syndrome to omental adipose tissue PAI-1 gene mRNA and plasma levels in obesity.. Obes Surg 2010; 20(4):492-9.
- Marceau P, Marceau S, Biron S, Hould FS, Lebel S, Lescelleur O, Biertho L, Kral JG. Long-term experience with duodenal switch in adolescents.. Obes Surg 2010; 20(12):1609-16.
- Biertho L, Biron S, Hould FS, Lebel S, Marceau S, Marceau P. Is biliopancreatic diversion with duodenal switch indicated for patients with body mass index <50 kg/m2?. Surg Obes Relat Dis 2010; 6(5):508-14.
- Martin J, Smith J, Bastien M, Cianflone K, Bussières J, Marceau S, Hould FS, Lebel S, Biertho L, Lescelleur O, Biron S, Bertrand F, Poirier P. Comparison between arterial and venous sampling of circulating hormones, substrates and peptides in severe obesity.. Clin Invest Med 2011; 34(2):E82.
- Martin J, Paquette C, Marceau S, Hould FS, Lebel S, Simard S, Dumesnil JG, Poirier P. Impact of orlistat-induced weight loss on diastolic function and heart rate variability in severely obese subjects with diabetes.. J Obes 2011; 2011(0):394658.
- Biertho L, Lebel S, Marceau S, Hould FS, Lescelleur O, Moustarah F, Simard S, Biron S, Marceau P. Perioperative complications in a consecutive series of 1000 duodenal switches.. Surg Obes Relat Dis 2013; 9(1):63-8.
- Hould FS. Collaboration between basic science researchers and bariatric surgeons is a win/win proposition: view from the chair.. Int J Obes (Lond) 2011; 35(0):S3-6.
- Faucher G, Guénard F, Bouchard L, Garneau V, Turcot V, Houde A, Tchernof A, Bergeron J, Deshaies Y, Hould FS, Lebel S, Marceau P, Vohl MC. Genetic contribution to C-reactive protein levels in severe obesity.. Mol Genet Metab 2012; 105(3):494-501.
- Turcot V, Bouchard L, Faucher G, Tchernof A, Deshaies Y, Pérusse L, Marceau P, Hould FS, Lebel S, Vohl MC. A polymorphism of the interferon-gamma-inducible protein 30 gene is associated with hyperglycemia in severely obese individuals.. Hum Genet 2012; 131(1):57-66.
- Li Z, Martin J, Poirier P, Caron-Cantin SM, Hould FS, Marceau S, Marceau P, Picard F. Upregulation of plasma insulin-like growth factor binding protein 2 levels after biliopancreatic diversion in humans.. Obesity (Silver Spring) 2012; 20(7):1469-73.
- Turcot V, Tchernof A, Deshaies Y, Pérusse L, Bélisle A, Marceau P, Hould FS, Lebel S, Vohl MC. Comparison of the dipeptidyl peptidase-4 gene methylation levels between severely obese subjects with and without the metabolic syndrome.. Diabetol Metab Syndr 2013; 5(1):4.
- Leblanc ME, Chouinard N, Turbide G, Hould FS, Poirier P. [Bariatric surgery: an effective intervention for morbid obesity].. Perspect Infirm 2013; 10(1):32-5.
- Leblanc ME, Croteau S, Ferland A, Bussières J, Cloutier L, Hould FS, Biertho L, Moustarah F, Marceau S, Poirier P. Blood pressure assessment in severe obesity; validation of a forearm approach.. Obesity (Silver Spring) 2013; 21(12):E533-41.
- Caron-Cantin SM, Martin J, Bastien M, Munkonda MN, Lu H, Cianflone K, Moustarah F, Biertho L, Marceau S, Hould FS, Bussières J, Poirier P.. Acute and Chronic Effects of Biliopancreatic Diversion with Duodenal Switch Surgery on Plasma Visfatin and Apelin Levels in Patients with Severe Obesity.. Obes Surg 2013; 23(11):1806-14.
- Piché ME, Martin J, Cianflone K, Bastien M, Marceau S, Biron S, Hould FS, Poirier P.. Changes in predicted cardiovascular disease risk after biliopancreatic diversion surgery in severely obese patients.. Metabolism 2014; 63(1):79-86.
- Biertho L, Lebel S, Marceau S, Hould FS, Lescelleur O, Marceau P, Biron S. Laparoscopic Sleeve Gastrectomy: With or without Duodenal Switch? A Consecutive Series of 800 Cases.. Dig Surg 2014; 31(1):48-54.
- Houde AA, Légaré C, Hould FS, Lebel S, Marceau P, Tchernof A, Vohl MC, Hivert MF, Bouchard L. Cross-tissue comparisons of leptin and adiponectin: DNA methylation profiles.. Adipocyte 2014; 3(2):132-40.
- Robert M, Bélanger P, Hould FS, Marceau S, Tchernof A, Biertho L.. Should metabolic surgery be offered in morbidly obese patients with type I diabetes?. Surg Obes Relat Dis 2014; 1550(14):00498-5.
- Baraboi ED, Li W, Labbé SM, Roy MC, Samson P, Hould FS, Lebel S, Marceau S, Biertho L, Richard D. Metabolic Changes Induced by the Biliopancreatic Diversion in Diet-Induced Obesity in Male Rats: The Contributions of Sleeve Gastrectomy and Duodenal Switch.. Endocrinology 2015; 156(4):1316-29.
- Marceau P, Biron S, Marceau S, Hould FS, Lebel S, Lescelleur O, Biertho L, Kral JG. Biliopancreatic diversion-duodenal switch: independent contributions of sleeve resection and duodenal exclusion.. Obes Surg 2014; 24(11):1843-9.
- Lessard J, Pelletier M, Biertho L, Biron S, Marceau S, Hould FS, Lebel S, Moustarah F, Lescelleur O, Marceau P, Tchernof A. Characterization of dedifferentiating human mature adipocytes from the visceral and subcutaneous fat compartments: fibroblast-activation protein alpha and dipeptidyl peptidase 4 as major components of matrix remodeling.. PLoS One 2015; 10(3):e0122065.
- Robert M, Belanger P, Hould FS, Marceau S, Tchernof A, Biertho L. Should metabolic surgery be offered in morbidly obese patients with type I diabetes?. Surg Obes Relat Dis 2015; 11(4):798-805.
- Marceau P, Biron S, Marceau S, Hould FS, Lebel S, Lescelleur O, Biertho L, Simard S, Kral JG. Long-Term Metabolic Outcomes 5 to 20 Years After Biliopancreatic Diversion.. Obes Surg 2015; 25(9):1584-93.
- Veilleux A, Mayeur S, Bérubé JC, Beaulieu JF, Tremblay E, Hould FS, Bossé Y, Richard D, Levy E. Altered intestinal functions and increased local inflammation in insulin-resistant obese subjects: a gene-expression profile analysis.. BMC Gastroenterol 2015; 15(0):119.
- Auclair A, Martin J, Bastien M, Bonneville N, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Després JP, Poirier P. Is There a Role for Visceral Adiposity in Inducing Type 2 Diabetes Remission in Severely Obese Patients Following Biliopancreatic Diversion with Duodenal Switch Surgery?. Obes Surg 2015; 0(0):Epub.
- Michaud A, Marchand GB, Nadeau M, Lebel S, Hould FS, Marceau S, Lescelleur O, Biron S, Tchernof A, Biertho L. Biliopancreatic Diversion with Duodenal Switch in the Elderly: Long-Term Results of a Matched-Control Study.. Obes Surg 2016; 26(2):350-60.
- Biertho L, Hould FS, Marceau S, Lebel S, Lescelleur O, Biron S. Current Outcomes of Laparoscopic Duodenal Switch.. Ann Surg Innov Res 2016; 10(0):1.
- Biertho L, Lebel S, Marceau S, Hould FS, Julien F, Biron S. Biliopancreatic Diversion with Duodenal Switch: Surgical Technique and Perioperative Care.. Surg Clin North Am 2016; 96(4):815-26.
- Auclair A, Martin J, Bastien M, Bonneville N, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Després JP, Poirier P. Is There a Role for Visceral Adiposity in Inducing Type 2 Diabetes Remission in Severely Obese Patients Following Biliopancreatic Diversion with Duodenal Switch Surgery?. Obes Surg 2016; 26(8):1717-27.
- de Toro-Martín J, Guénard F, Tchernof A, Deshaies Y, Pérusse L, Hould FS, Lebel S, Marceau P, Vohl MC. Methylation quantitative trait loci within the TOMM20 gene are associated with metabolic syndrome-related lipid alterations in severely obese subjects.. Diabetol Metab Syndr 2016; 8(0):55.
- Mayeur S, Veilleux A, Pouliot Y, Lamarche B, Beaulieu JF, Hould FS, Richard D, Tchernof A, Levy E. Plasma Lactoferrin Levels Positively Correlate with Insulin Resistance despite an Inverse Association with Total Adiposity in Lean and Severely Obese Patients.. PLoS One 2016; 11(11):e0166138.
- Robert M, Belanger P, Hould FS, Marceau S, Tchernof A, Biertho L. Reply to Letter to the Editor: Metabolic surgery in morbidly obese patients with type 1 diabetes.. Surg Obes Relat Dis 2016; 12(3):721-2.
- Auclair A, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Julien F, Lescelleur O, Lacasse Y, Piché ME, Cianflone K, Parlee SD, Goralski K, Martin J, Bastien M, St-Pierre DH, Poirier P. Bariatric Surgery-Induced Resolution of Hypertension and Obstructive Sleep Apnea: Impact of Modulation of Body Fat, Ectopic Fat, Autonomic Nervous Activity, Inflammatory and Adipokine Profiles.. Obes Surg 2017; 27(12):3156-64.
- Grenier-Larouche T, Carreau AM, Geloën A, Frisch F, Biertho L, Marceau S, Lebel S, Hould FS, Richard D, Tchernof A, Carpentier AC. Fatty Acid Metabolic Remodelling During Type 2 Diabetes Remission After Bariatric Surgery.. Diabetes 2017; 66(11):2743-55.
- Boyer M, Piché ME, Auclair A, Grenier-Larouche T, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Julien F, Martin J, Tchernof A, Carpentier AC, Poirier P, Arsenault BJ. Acute and Chronic Impact of Bariatric Surgery on Plasma LDL Cholesterol and PCSK9 Levels in Patients With Severe Obesity.. J Clin Endocrinol Metab 2017; 102(11):4023-4030.
- Caron M, Hould FS, Lescelleur O, Marceau S, Lebel S, Julien F, Simard S, Biertho L. Long-term nutritional impact of sleeve gastrectomy.. Surg Obes Relat Dis 2017; 13(10):1664-1673.
- Tardio V, Blais JP, Julien AS, Douville P, Lebel S, Biertho L, Marceau S, Hould FS, Gagnon C. Serum Parathyroid Hormone and 25-Hydroxyvitamin D Concentrations Before and After Biliopancreatic Diversion.. Obes Surg 2018; 28(7):1886-1894.
- Cloutier A, Lebel S, Hould FS, Julien F, Marceau S, Bouvet L, Simard S, Biertho L. Long alimentary limb duodenal switch (LADS): a short-term prospective randomized trial.. Surg Obes Relat Dis 2018; 14(1):30-37.
- Bourgeois R, Piché ME, Auclair A, Grenier-Larouche T, Mitchell PL, Poirier P, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Julien F, Martin J, Tchernof A, Mathieu P, Carpentier AC, Arsenault BJ. Acute and chronic effect of bariatric surgery on circulating autotaxin levels.. Physiol Rep 2019; 7(5):e14004.
- Biertho L, Thériault C, Bouvet L, Marceau S, Hould FS, Lebel S, Julien F, Tchernof A. Second-stage duodenal switch for sleeve gastrectomy failure: A matched controlled trial.. Surg Obes Relat Dis 2018; 14(10):1570-1579.
- Leblanc MÈ, Auclair A, Leclerc J, Bussières J, Agharazii M, Hould FS, Marceau S, Brassard P, Godbout C, Grenier A, Cloutier L, Poirier P. Blood Pressure Measurement in Severely Obese Patients: Validation of the Forearm Approach in Different Arm Positions.. Am J Hypertens 2019; 32(2):175-185.
- Pirlet C, Biertho L, Poirier P, Marceau S, Marceau P, Biron S, Hould FS, Lebel S, Lescelleur O, Julien F, Lafortune-Payette A, Bertrand OF. Comparison of Short and Long Term Cardiovascular Outcomes After Bariatric Surgery in Patients With vs Without Coronary Artery Disease.. Am J Cardiol 2020; 125(1):40-47.
- de Toro-Martín J, Guénard F, Tchernof A, Hould FS, Lebel S, Julien F, Marceau S, Vohl MC.. Body mass index is associated with epigenetic age acceleration in the visceral adipose tissue of subjects with severe obesity.. Clin Epigenetics 2019; 11(1):172.
- Kapeluto JE, Tchernof A, Masckauchan D, Biron S, Marceau S, Hould FS, Lebel S, Lescelleur O, Julien F, Biertho L. Ten-year remission rates in insulin-treated type 2 diabetes after biliopancreatic diversion with duodenal switch.. Surg Obes Relat Dis 2020; 16(11):1701-1712.
- Auclair A, Harvey J, Leclerc J, Piché ME, O'Connor K, Nadreau É, Pettigrew M, Haykowsky MJ, Marceau S, Biertho L, Hould FS, Lebel S, Biron S, Julien F, Bouvet-Bouchard L, Lescelleur O, Poirier P. Determinants of Cardiorespiratory Fitness After Bariatric Surgery: Insights From a Randomised Controlled Trial of a Supervised Training Program.. Can J Cardiol 2021; 37(2):251-259.
- Després AA, Piché ME, Auclair A, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Julien F, Martin J, Tchernof A, Mathieu P, Poirier P, Arsenault BJ. Acute and Chronic Impact of Biliopancreatic Diversion with Duodenal Switch Surgery on Plasma Lipoprotein(a) Levels in Patients with Severe Obesity.. Obes Surg 2020; 30(10):3714-3720.
- Tardif I, Auclair A, Piché ME, Biertho L, Marceau S, Hould FS, Biron S, Lebel S, Lescelleur O, Poirier P. Impact of a 12-Week Randomized Exercise Training Program on Lipid Profile in Severely Obese Patients Following Bariatric Surgery.. Obes Surg 2020; 30(8):3030-3036.
- Pirlet C, Voisine P, Poirier P, Cieza T, Ruzsa Z, Bagur R, Julien F, Hould FS, Biertho L, Bertrand OF. Outcomes in Patients with Obesity and Coronary Artery Disease with and Without Bariatric Surgery.. Obes Surg 2020; 30(6):2085-2092.
- Malo FC, Marion A, Rioux A, Lebel S, Hould FS, Julien F, Marceau S, Lescelleur O, Lafortune A, Bouvet-Bouchard L, Biertho L. Long Alimentary Limb Duodenal Switch (LADS): an Exploratory Randomized Trial, Results at 2 Years.. Obes Surg 2020; 30(12):5047-5058.
- Marzouk M, Baillot R, Kalavrouziotis D, Amhis N, Nader J, Hould FS, Biertho L, Mohammadi S, Malas T. Early to midterm survival of patients with deep sternal wound infection managed with laparoscopically harvested omentum.. J Card Surg 2021; 36(11):4083-4089.
- Faramia J, Hao Z, Mumphrey MB, Townsend RL, Miard S, Carreau AM, Nadeau M, Frisch F, Baraboi ED, Grenier-Larouche T, Noll C, Li M, Biertho L, Marceau S, Hould FS, Lebel S, Morrison CD, Münzberg H, Richard D, Carpentier AC, Tchernof A, Berthoud HR, Picard F. IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery.. Cell Rep Med 2021; 2(4):100248.
- Gagnon G, Carreau AM, Cloutier-Langevin C, Plante AS, Weisnagel SJ, Marceau S, Biertho L, Hould FS, Camirand-Lemyre F, Tchernof A, Morisset AS.. Trimester-specific gestational weight gain in women with and without previous bariatric surgeries.. Eur J Obstet Gynecol Reprod Biol 2022; 270(0):252-258.
- Ostinelli G, Laforest S, Denham SG, Gauthier MF, Drolet-Labelle V, Scott E, Hould FS, Marceau S, Homer NZM, Bégin C, Andrew R, Tchernof A. Increased Adipose Tissue Indices of Androgen Catabolism and Aromatization in Women With Metabolic Dysfunction.. J Clin Endocrinol Metab 2022; 107(8):e3330-e3342.
- Baillargeon D, Greenblatt M, Côté M, Nadeau M, Couture CY, Hould FS, Bouvet-Bouchard L, Tchernof A, Biertho L. Prevalence of Helicobacter pylori Infection in Bariatric Surgery Patients.. Obes Surg 2023; 33(7):2132-2138.